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Showing 1–6 of 6 results
Advanced filters: Author: James A. Dumesic Clear advanced filters

  • Khetarpal et al. show that the metabolic regulator PGC-1α is essential in heart muscle cells for exercise-driven cardiac growth, and that suppression of the stress-induced myokine GDF15 is required to enable cardiomyocyte adaptations to training.

    • Sumeet A. Khetarpal
    • Haobo Li
    • Anthony Rosenzweig
    Research
    Nature Cardiovascular Research
    Volume: 4, P: 1277-1294

  • The choice of solvent system has important implications regarding the catalytic upgrading of carbohydrate-containing biomass. Here, Dumesic and co-workers study solvation effects in organic solvent/water mixtures and employ the obtained information to control the rate and selectivity of the acid-catalysed dehydration of fructose.

    • Max A. Mellmer
    • Chotitath Sanpitakseree
    • James A. Dumesic
    Research
    Nature Catalysis
    Volume: 1, P: 199-207

  • Despite the potential advantages of using polar aprotic solvents for biomass upgrading reactions, fundamental understanding of these solvation effects is limited at present. Here, the authors show that further increases in catalyst performance in polar aprotic solvents can be achieved through the addition of inorganic salts.

    • Max A. Mellmer
    • Chotitath Sanpitakseree
    • James A. Dumesic
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • Here, the authors show that anchoring of the PRC2 complex to its own sites requires nuclear condensation of Ccc1, a H3K27me3 reader in the yeast Cryptococcus neoformans, suggesting a functional role for condensates in ensuring heterochromatin fidelity.

    • Sujin Lee
    • Stephen Abini-Agbomson
    • Hiten D. Madhani
    Research
    Nature Structural & Molecular Biology
    Volume: 30, P: 891-901

  • Ethanol has emerged as a potential alternative feedstock for the synthesis of middle-distillate transportation fuels. This Review describes the chemistry of ethanol-to-distillate processes and challenges associated with improving current technologies and implementing new ones.

    • Nathaniel M. Eagan
    • Mrunmayi D. Kumbhalkar
    • George W. Huber
    Reviews
    Nature Reviews Chemistry
    Volume: 3, P: 223-249