Nature Search

Postnatal Cardiovascular and Metabolic Responses to a Single Intramuscular Dose of Betamethasone in Fetal Sheep Born Prematurely by Cesarean Section

James F Padbury
Daniel H Polk
Alan H Jobe
Research01 Nov 1995
Pediatric Research

Volume: 38, P: 709-715
Neonatal Adaptation: Naloxone Increases the Catecholamine Surge at Birth

James F Padbury
Youtaro Agata
Carlos C Callegari
Research01 Jun 1987
Pediatric Research

Volume: 21, P: 590-593
Suffering in silence: the tolerance of DNA damage

Errol C. Friedberg
Reviews15 Nov 2005
Nature Reviews Molecular Cell Biology

Volume: 6, P: 943-953
The Effect of Chemical Sympathectomy on Catecholamine Release at Birth

Youtaro Agata
James F Padbury
James A Humme
Research01 Dec 1986
Pediatric Research

Volume: 20, P: 1338-1344
Corticosteroids and Fetal Intervention Interact to Alter Lung Maturation in Preterm Lambs

Bannie L Tabor
James F Lewis
Alan H Jobe
Research01 Apr 1994
Pediatric Research

Volume: 35, P: 479-483
Exome sequencing of familial high-grade serous ovarian carcinoma reveals heterogeneity for rare candidate susceptibility genes

Around half of the heritability underpinning familial high-grade serous ovarian carcinoma remains unidentified. Here, the authors show that extremely rare protein encoding loss-of-function variants, with a high degree of genetic heterogeneity, may account for some of this missing heritability.

Deepak N. Subramanian
Magnus Zethoven
Ian G. Campbell
ResearchOpen Access02 Apr 2020
Nature Communications

Volume: 11, P: 1-11
Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs characterized by PD-L1 or CD80

Shahbandi et al. find that cancer cells that survive chemotherapy (CT) activate two immune-modulatory programs characterized by IFN response genes and CD274 or p53 signaling and CD80 expression. Targeting these pathways enhances the CT response.

Ashkan Shahbandi
Fang-Yen Chiu
James G. Jackson
Research08 Dec 2022
Nature Cancer

Volume: 3, P: 1513-1533
Naloxone Potentiates Epinephrine Release during Hypoxia in Fetal Sheep: Dose Response and Cardiovascular Effects

Alma Martinez
James Padbury
James Humme
Research01 Apr 1988
Pediatric Research

Volume: 23, P: 343-347
Metabolic Clearance and Plasma Appearance Rates of Catecholamines in Preterm and Term Fetal Sheep

James F Padbury
John K Ludlow
Youtaro Agata
Research01 Oct 1986
Pediatric Research

Volume: 20, P: 992-995
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Genome-wide analyses identify common variants associated with 11 distinct neuropathology endophenotypes, providing insights into the mechanisms underlying the genetic risk of Alzheimer’s disease and related dementias.

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
ResearchOpen Access08 Oct 2024
Nature Genetics

Volume: 56, P: 2407-2421
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Non invasive monitoring for spaceflight associated neuro ocular syndrome: responding to a need for In flight methodologies

Elana A. Meer
Lauren E. Church
Aenor J. Sawyer
ResearchOpen Access01 Sept 2025
npj Microgravity

Volume: 11, P: 1-8
Investigative needle core biopsies support multimodal deep-data generation in glioblastoma

Stereotactic needle biopsies are currently performed for diagnosis only in glioblastoma; this study highlights the depth of information available through multi-omics analysis.

Kenny K. H. Yu
Sreyashi Basu
Nathalie Y. R. Agar
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-23
CD10⁻/ALDH⁻ cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy

Brendan Ffrench
Claudia Gasch
Michael F Gallagher
ResearchOpen Access19 Oct 2017
Cell Death & Disease

Volume: 8, P: e3128
Author Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1788
Publisher Correction: GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Lincoln M. P. Shade
Yuriko Katsumata
David W. Fardo
Amendments and CorrectionsOpen Access17 Jun 2025
Nature Genetics

Volume: 57, P: 1791
Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways

Nephritis is a major cause of lupus morbidity. Putterman and colleagues use single-cell RNA sequencing on human renal and skin biopsies to describe the expression landscape associated with lupus nephritis.

Evan Der
Hemant Suryawanshi
Fan Zhang
Research20 May 2019
Nature Immunology

Volume: 20, P: 915-927
COCKAYNE SYNDROME (CS) MASQUERADING AS SECKEL SYNDROME (SS)

James M Lewis
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 229
Plasma Thyroid Hormones and Prolactin in Premature Infants and Their Mothers after Prenatal Treatment with Thyrotropin-Releasing Hormone

Philip L Ballard
Roberta A Ballard
Ian Gross
Research01 Dec 1992
Pediatric Research

Volume: 32, P: 673-678
EFFECT OF HUMAN GROWTH HORMONE (HGH) ON THE IMMUNE SYSTEM (IS) OF GH DEFICIENT CHILDREN

Robert Rapaport
James Oleskeo
Houman Ahdieh
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 174
Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial

The combination of neoadjuvant nivolumab, ipilimumab and chemotherapy showed promising efficacy in patients with resectable non-small cell lung cancer, with higher tumor immune cell infiltration and tertiary lymphoid structures after treatment compared with neoadjuvant nivolumab plus chemotherapy.

Tina Cascone
Cheuk H. Leung
Boris Sepesi
ResearchOpen Access16 Mar 2023
Nature Medicine

Volume: 29, P: 593-604
Pilot study of Tremelimumab with and without cryoablation in patients with metastatic renal cell carcinoma

Anti-CTLA4 therapy has not been comprehensively explored for the treatment of metastatic renal cell carcinoma (mRCC). Here, in a pilot study of anti-CTLA4 therapy with or without cryoablation in mRCC, the authors report that the combination is feasible and enhances immune infiltration in patients with metastatic clear cell histology.

Matthew T. Campbell
Surena F. Matin
Padmanee Sharma
ResearchOpen Access04 Nov 2021
Nature Communications

Volume: 12, P: 1-12
Effects of Thyroid Hormone on Myocardial Adrenergic β-Receptor Responsiveness and Function during Late Gestation

Einat Birk
Michael R Tyndall
James M Roberts
Research01 May 1992
Pediatric Research

Volume: 31, P: 468-473
Prolonged β-Agonist Infusion Does Not Induce Desensitization or Down-Regulation of β-Adrenergic Receptors in Newborn Sheep

Howard M Stein
Kotaro Oyama
James F Padbury
Research01 May 1992
Pediatric Research

Volume: 31, P: 462-466
Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes characterized by the absence of cancer and the presence of non-caseating granulomas, in patients with non-small cell lung cancer following neoadjuvant ICI treatment.

Tina Cascone
Annikka Weissferdt
Boris Sepesi
ResearchOpen Access19 Aug 2021
Nature Communications

Volume: 12, P: 1-15
Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array

Edward J Saunders
Tokhir Dadaev
Zsofia Kote-Jarai
ResearchOpen Access10 Mar 2016
British Journal of Cancer

Volume: 114, P: 945-952
Neonatal Adaptation: Cardiac Adrenergic Effector Mechanisms after Birth in Newborn Sheep

David M Habib
James F Padbury
Elizabeth E Burnell
Research01 Jan 1991
Pediatric Research

Volume: 29, P: 98-103
RENAL AND CARDIOVASCULAR FUNCTION IN PRETERM NEWBORN LAMBS FOLLOWING ANTENATAL FETAL OR MATERNAL BETAMETHASONE ADMINISTRATION. † 1159

Lynne M Berry
Max G Ervin
Alan H Jobe
Research01 Apr 1996
Pediatric Research

Volume: 39, P: 196
The Role of β-Adrenoreceptor Stimulation and Contractile State in the Preterm Lamb's Response to Altered Ductus Arteriosus Patency

Ronald I Clyman
David Teitel
Francoise Mauray
Research01 Mar 1988
Pediatric Research

Volume: 23, P: 316-322
Hemodynamic and Neuroendocrine Adaptations of the Preterm Lamb Left Ventricle to Acutely Increased Afterload

Barry G Baylen
Youtaro Agata
George C Emmanouilides
Research01 Oct 1989
Pediatric Research

Volume: 26, P: 336-342
VITAMIN E (VE) KINETICS IN INFANTS <1500 GRAMS: INTRAMUSCULAR (IM) VS. ORAL ADMINISTRATION

Alfonso Pantoja
Christinia Ukrainski
James Mathis
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 157
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration

Erica S. Tsang
Veronika Csizmok
Daniel J. Renouf
ResearchOpen Access24 Mar 2023
npj Precision Oncology

Volume: 7, P: 1-12
Transcriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region

Hernan A. Bazan
Surjyadipta Bhattacharjee
Nicolas G. Bazan
ResearchOpen Access15 May 2024
Scientific Reports

Volume: 14, P: 1-35
Long non-coding RNA ZFAS1 is a major regulator of epithelial-mesenchymal transition through miR-200/ZEB1/E-cadherin, vimentin signaling in colon adenocarcinoma

Stephen J. O’Brien
Casey Fiechter
Susan Galandiuk
ResearchOpen Access26 Mar 2021
Cell Death Discovery

Volume: 7, P: 1-14
Single Dose Fetal Betamethasone Administration Stabilizes Postnatal Glomerular Filtration Rate and Alters Endocrine Function in Premature Lambs

M Gore Ervin
Lynne M Berry
Daniel H Polk
Research01 Nov 1996
Pediatric Research

Volume: 40, P: 645-651
Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies

Diana L. Price
Edward Rockenstein
Eliezer Masliah
ResearchOpen Access08 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
Individual Differences in Attentional Bias Associated with Cocaine Dependence Are Related to Varying Engagement of Neural Processing Networks

Clint D Kilts
Ashley Kennedy
G Andrew James
Research07 Nov 2013
Neuropsychopharmacology

Volume: 39, P: 1135-1147
Blood-based microRNAs as biomarkers for the diagnosis of colorectal cancer: a systematic review and meta-analysis

Jane V Carter
Norman J Galbraith
Susan Galandiuk
ResearchOpen Access02 Feb 2017
British Journal of Cancer

Volume: 116, P: 762-774

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