Nature Search

High-throughput multiplexed fluorescence-activated droplet sorting

Ouriel Caen
Simon Schütz
Valérie Taly
ResearchOpen Access22 Oct 2018
Microsystems & Nanoengineering

Volume: 4, P: 1-10
Controlling molecular transport in minimal emulsions

Emulsion droplets have many biotechnological applications, such as parallelized single cell analysis. Here, Gruner et al. introduce the concept of the minimal emulsions in a microfluidic device that allows full control of molecular transport between emulsion droplets.

Philipp Gruner
Birte Riechers
Jean-Christophe Baret
ResearchOpen Access22 Jan 2016
Nature Communications

Volume: 7, P: 1-9
Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions

Generating artificial cells able to carry out metabolic activities out-of-equilibrium is a current challenge in synthetic biology. Here the authors use a microfluidic platform for integration and analysis of minimal metabolic reactions in artificial microcompartments formed of water-in-oil droplets.

Thomas Beneyton
Dorothee Krafft
Jean-Christophe Baret
ResearchOpen Access19 Jun 2018
Nature Communications

Volume: 9, P: 1-10
A new-to-nature carboxylation module to improve natural and synthetic CO₂ fixation

Biological CO₂ fixation is restricted to few enzymes and pathways, limiting its value in environmental protection and agricultural productivity. Now, a new-to-nature CO₂-fixing enzyme allows CO₂-dependent assimilation of glycolate in a designed pathway, and its use for different applications is demonstrated.

Marieke Scheffen
Daniel G. Marchal
Tobias J. Erb
ResearchOpen Access04 Jan 2021
Nature Catalysis

Volume: 4, P: 105-115
Author Correction: High throughput single cell counting in droplet-based microfluidics

Heng Lu
Ouriel Caen
Valérie Taly
Amendments and CorrectionsOpen Access17 Jun 2020
Scientific Reports

Volume: 10, P: 1
Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

A microfluidics method to generate giant, copolymer-stabilized liposomes is presented. These vesicles are functionalized with distinct proteins to recapitulate cellular processes.

Marian Weiss
Johannes Patrick Frohnmayer
Joachim P. Spatz
Research16 Oct 2017
Nature Materials

Volume: 17, P: 89-96
Variable inter and intraspecies alkaline phosphatase activity within single cells of revived dinoflagellates

Mathias Girault
Raffaele Siano
Jean-Christophe Baret
Research10 Feb 2021
The ISME Journal

Volume: 15, P: 2057-2069
Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation

Simone H. Oldenburg
Lionel Buisson
Jean-Christophe Baret
ResearchOpen Access14 Sept 2021
Scientific Reports

Volume: 11, P: 1-12
High throughput single cell counting in droplet-based microfluidics

Heng Lu
Ouriel Caen
Valérie Taly
ResearchOpen Access02 May 2017
Scientific Reports

Volume: 7, P: 1-9
The Microfluidic Jukebox

Say Hwa Tan
Florine Maes
Jean-Christophe Baret
ResearchOpen Access30 Apr 2014
Scientific Reports

Volume: 4, P: 1-8
Droplet-based microfluidics

Droplet-based microfluidic systems generate microlitre droplets, giving users precise control over the chemical and biological contents of each droplet. In this Primer, Moragues et al. discuss the optimal use of droplet-based microfluidic systems and the most successful applications in biological and chemical sciences.

Thomas Moragues
Diana Arguijo
Andrew D. Griffiths
Reviews20 Apr 2023
Nature Reviews Methods Primers

Volume: 3, P: 1-22
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

Kim Valette et al. perform a genomic study on asthma integrating genome-wide association study, functional mapping using lung and blood transcriptome-wide profiles, as well as Mendelian randomization. They show candidate causal genes expressed in lung and blood tissues that are putative therapeutic targets for asthma.

Kim Valette
Zhonglin Li
Yohan Bossé
ResearchOpen Access08 Jun 2021
Communications Biology

Volume: 4, P: 1-15

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High-throughput multiplexed fluorescence-activated droplet sorting

Controlling molecular transport in minimal emulsions

Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions

A new-to-nature carboxylation module to improve natural and synthetic CO₂ fixation

Author Correction: High throughput single cell counting in droplet-based microfluidics

Sequential bottom-up assembly of mechanically stabilized synthetic cells by microfluidics

Variable inter and intraspecies alkaline phosphatase activity within single cells of revived dinoflagellates

Confining Trypanosoma brucei in emulsion droplets reveals population variabilities in division rates and improves in vitro cultivation

High throughput single cell counting in droplet-based microfluidics

The Microfluidic Jukebox

Droplet-based microfluidics

Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

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