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Showing 1–3 of 3 results

Advanced filters: Author: Jean-Francois Taly Clear advanced filters

Circulating tumor DNA strongly predicts efficacy of chemotherapy plus immune checkpoint inhibitors in patients with advanced gastro-esophageal adenocarcinoma

Tougeron et al. evaluate the prognostic value of circulating tumor DNA (ctDNA) in predicting the efficacy of immune checkpoint inhibitors (ICI) plus chemotherapy in advanced gastric adenocarcinoma. An early decrease in ctDNA concentration is associated with a worse objective response rate, shorter progression free survival and overall survival.

David Tougeron
Christophe Louvet
Pierre Laurent-Puig
ResearchOpen Access24 Apr 2025
Communications Medicine

Volume: 5, P: 1-11
Using the T-Coffee package to build multiple sequence alignments of protein, RNA, DNA sequences and 3D structures

Jean-Francois Taly
Cedrik Magis
Cedric Notredame
Protocols06 Oct 2011
Nature Protocols

Volume: 6, P: 1669-1682
Massively parallel and multiparameter titration of biochemical assays with droplet microfluidics

Titration of the optimal ratios of multicomponent biochemical reactions can be a laborious task. This protocol describes how to explore ∼10,000 combinations of concentrations of one to three reaction components with a droplet-based microfluidics platform.

Alexandre Baccouche
Shu Okumura
Anthony J Genot
Protocols24 Aug 2017
Nature Protocols

Volume: 12, P: 1912-1932

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