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Showing 1–3 of 3 results
Advanced filters: Author: Jerrin Thomas George Clear advanced filters

  • In this study, the authors determine the structure of a Type I-A retron from E. coli FORC82 and reveal the functional interplay between Reverse Transcriptases (RTs) and Structural Maintenance of Chromosomes (SMC) ATPases.’

    • Jerrin Thomas George
    • Nathaniel Burman
    • Blake Wiedenheft
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • Site-specific attachment of a programmable motif, such as a synthetic nucleic acid tag, on a target protein can facilitate functional studies of proteins in cells or modulation of protein activity. Now, a small genetically encoded peptide enables the templated incorporation of a peptide nucleic acid tag onto membrane proteins in live cells.

    • Jerrin Thomas George
    • Sarit S. Agasti
    News & Views
    Nature Chemistry
    Volume: 13, P: 5-6

  • CRISPR-associated transposons exploit a proofreading checkpoint to ensure high-fidelity selection of genomic sites for DNA insertion through specific recruitment of TnsC oligomers by the Cascade complex.

    • Florian T. Hoffmann
    • Minjoo Kim
    • Samuel H. Sternberg
    Research
    Nature
    Volume: 609, P: 384-393