Nature Search

A machine learning model for optimizing treatment of patients with poorly controlled type 2 diabetes

Shi, Liu et al. develop a SGLT-2i/GLP-1RA Decision Score to support personalized selection between the two therapies. The results show that the model achieved good predictive performance and offers a practical tool for optimizing SGLT-2i and GLP-1RA therapy decisions for patients with type 2 diabetes.

Juan Shi
Cong Liu
Weiqing Wang
ResearchOpen Access17 Feb 2026
Communications Medicine

P: 1-11
Scalable manufacture of nearly pure-phase metallic MoS₂ nanosheets

A microwave-assisted process is developed for the rapid and scalable manufacture of pure-phase metallic MoS₂ nanosheets, enabling practical electrochemical devices for energy applications.

Ziwei Jeffrey Yang
Zhuangnan Li
Manish Chhowalla
ResearchOpen Access29 Jan 2026
Nature Materials

P: 1-7
Metal-free directed sp²-C–H borylation

A method for the site-selective C–H borylation of arenes and heteroarenes is described, in which BBr₃ acts as both a reagent and a catalyst.

Jiahang Lv
Xiangyang Chen
Zhuangzhi Shi
Research30 Sept 2019
Nature

Volume: 575, P: 336-340
Understanding the degradation complexity of ultrahigh-energy lithium metal batteries

This Review discusses the lifespan failure chemistry of lithium metal batteries beyond 600 Wh kg⁻¹, highlighting the challenges in assessing active Li loss. We correlate material degradation, cell parameters, cell assembly and operating conditions to the overall performance and failure of a lithium metal battery.

Wei Deng
Bao Qiu
Ying Shirley Meng
Reviews20 Feb 2026
Nature Reviews Chemistry

P: 1-17
Chemical reprogramming of fibroblasts into retinal pigment epithelium cells for vision restoration

This study presents a two-step chemical reprogramming strategy that converts fibroblasts into functional retinal pigment epithelium cells, offering a safe and scalable alternative for vision restoration in retinal degenerative diseases.

Shasha Li
Hui Liu
Jianzhong Su
ResearchOpen Access09 Dec 2025
Nature Communications

Volume: 17, P: 1-23
Interplay of ECM organization, ROCK signaling, and cell polarity drives mesothelium formation and lung growth

The authors show that ECM organization, ROCK signaling and cell polarity interact to promote mesothelium formation to direct lung growth. Frem2 deficiency disrupts these interactions in the mesothelium to inhibit the growth of the lungs in mice and humans.

Xinyuan Liu
Bingying Lin
Wenguang Yin
ResearchOpen Access30 Oct 2025
Nature Communications

Volume: 16, P: 1-19
Inhibition of halide oxidation and deprotonation of organic cations with dimethylammonium formate for air-processed p–i–n perovskite solar cells

Manufacturing of perovskite solar cells under ambient conditions is desirable. Meng et al. show that dimethylammonium formate suppresses halide oxidation and deprotonation of organic cations, enabling air-processed inverted solar cells with 24.7% efficiency.

Hongguang Meng
Kaitian Mao
Jixian Xu
Research26 Feb 2024
Nature Energy

Volume: 9, P: 536-547
Iron phthalocyanine with coordination induced electronic localization to boost oxygen reduction reaction

Iron phthalocyanine with a 2D structure and symmetric electron distribution around Fe-N₄ active sites is not optimal for O₂ adsorption and activation. Here, the authors report an axial Fe–O coordination induced electronic localization strategy to enhance oxygen reduction reaction performance.

Kejun Chen
Kang Liu
Min Liu
ResearchOpen Access20 Aug 2020
Nature Communications

Volume: 11, P: 1-8
Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

Jiahang Song
Junfeng Zhang
Xiaoke Di
Amendments and Corrections27 Jun 2025
Oncogene

Volume: 44, P: 2563-2564
Design of waveguide with double layer diffractive optical elements for augmented reality displays

Jiahang Zhang
Siqi Liu
Xin Tan
ResearchOpen Access16 Oct 2024
Scientific Reports

Volume: 14, P: 1-15
Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

Jiahang Song
Junfeng Zhang
Xiaoke Di
Research14 May 2024
Oncogene

Volume: 43, P: 2000-2014
Accurate prediction of disease-free and overall survival in non-small cell lung cancer using patient-level multimodal weakly supervised learning

Yongmeng Li
Xiaodong Chai
Nanying Che
ResearchOpen Access19 Jun 2025
npj Precision Oncology

Volume: 9, P: 1-10
CpG-binding protein CFP1 promotes ovarian cancer cell proliferation by regulating BST2 transcription

Liu-Qing Yang
Han-Yin Hu
Wei-Wei Pan
ResearchOpen Access21 Jul 2022
Cancer Gene Therapy

Volume: 29, P: 1895-1907
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Zhou et al. utilise deep learning to improve polygenic risk analysis for Alzheimer’s disease. Their computational approach outperforms existing statistical methods and helps to identify potential biological mechanisms of Alzheimer’s disease risk.

Xiaopu Zhou
Yu Chen
Nancy Y. Ip
ResearchOpen Access06 Apr 2023
Communications Medicine

Volume: 3, P: 1-20
Low thigh muscle strength in relation to myosteatosis in patients with type 2 diabetes mellitus

Yilong Huang
Jun Yan
Bo He
ResearchOpen Access02 Feb 2023
Scientific Reports

Volume: 13, P: 1-10
CRMP2 derived from cancer associated fibroblasts facilitates progression of ovarian cancer via HIF-1α-glycolysis signaling pathway

Yunfeng Jin
Saiyan Bian
Hua Jiang
ResearchOpen Access04 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-13
Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury

Schematic diagram of the protective effect of MSC-derived exosomes on maintaining SLC7A11 function during ferroptosis involved in CCl₄-induced ALI.

Feiyan Lin
Wenyi Chen
Hongcui Cao
ResearchOpen Access26 Mar 2022
Cell Death & Disease

Volume: 13, P: 1-11

Search

A machine learning model for optimizing treatment of patients with poorly controlled type 2 diabetes

Scalable manufacture of nearly pure-phase metallic MoS₂ nanosheets

Metal-free directed sp²-C–H borylation

Understanding the degradation complexity of ultrahigh-energy lithium metal batteries

Chemical reprogramming of fibroblasts into retinal pigment epithelium cells for vision restoration

Interplay of ECM organization, ROCK signaling, and cell polarity drives mesothelium formation and lung growth

Inhibition of halide oxidation and deprotonation of organic cations with dimethylammonium formate for air-processed p–i–n perovskite solar cells

Iron phthalocyanine with coordination induced electronic localization to boost oxygen reduction reaction

Correction: Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

Design of waveguide with double layer diffractive optical elements for augmented reality displays

Hypoxia inhibits ferritinophagy-mediated ferroptosis in esophageal squamous cell carcinoma via the USP2-NCOA4 axis

Accurate prediction of disease-free and overall survival in non-small cell lung cancer using patient-level multimodal weakly supervised learning

CpG-binding protein CFP1 promotes ovarian cancer cell proliferation by regulating BST2 transcription

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Low thigh muscle strength in relation to myosteatosis in patients with type 2 diabetes mellitus

CRMP2 derived from cancer associated fibroblasts facilitates progression of ovarian cancer via HIF-1α-glycolysis signaling pathway

Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury

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