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Showing 1–5 of 5 results

Advanced filters: Author: Jiangqing Chen Clear advanced filters

Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses

BiKE-secreting CAR-T cells and NK cells combine to suppress tumours in mouse models.

Ya Fan
Yanting Duan
Jie Sun
Research14 Jul 2025
Nature Biomedical Engineering

P: 1-14
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastases

CAR T cells engineered to express IL-10 eradicate solid tumors and metastases.

Yang Zhao
Jiangqing Chen
Li Tang
Research02 Jan 2024
Nature Biotechnology

Volume: 42, P: 1693-1704
Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P₂/PI(3,4)P₂

Phosphatidylinositol phosphates (PIPs) and cholesterol are known to regulate the function of late endosomes and lysosomes (LELs). Here authors unveil a mechanism by which PI(4,5)P₂/PI(3,4)P₂ allosterically enhances ORP1-mediated cholesterol exit from LELs.

Jiangqing Dong
Ximing Du
Jia-Wei Wu
ResearchOpen Access19 Feb 2019
Nature Communications

Volume: 10, P: 1-16
A multi-scale remote sensing semantic segmentation model with boundary enhancement based on UNetFormer

JiangQing Wang
Ting Chen
QuanJie Song
ResearchOpen Access27 Apr 2025
Scientific Reports

Volume: 15, P: 1-19
Inserting EF1α-driven CD7-specific CAR at CD7 locus reduces fratricide and enhances tumor rejection

Jie Jiang
Jiangqing Chen
Jie Sun
Research30 Jun 2023
Leukemia

Volume: 37, P: 1660-1670