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Signal Transduction and Targeted Therapy (1)
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A-to-I edited SNHG3 promotes non-small cell lung cancer metastasis by promoting fatty acid oxidation and resisting ferroptosis

Adenosine-to-inosine editing in SNHG3 (c.1746 A > I) drives non-small cell lung (NSCLC) cancer metastasis and docetaxel resistance by enhancing SSRP1 binding and altering fatty acid metabolism. Targeting this hyper-edited RNA may improve cancer therapy.

Shizhen Chen
Amei Zhuo
Lei Yang
ResearchOpen Access02 Sept 2025
Communications Biology

Volume: 8, P: 1-16
Metformin escape in prostate cancer by activating the PTGR1 transcriptional program through a novel super-enhancer

Jianheng Ye
Shanghua Cai
Weide Zhong
ResearchOpen Access16 Aug 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-15
Role of Signal Regulatory Protein α in Arsenic Trioxide-induced Promyelocytic Leukemia Cell Apoptosis

Chaoyun Pan
Dihan Zhu
Ke Zen
ResearchOpen Access24 Mar 2016
Scientific Reports

Volume: 6, P: 1-12