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OsCDPK24 and OsCDPK28 phosphorylate heat shock factor OsHSFA4d to orchestrate abiotic and biotic stress responses in rice

Fang et al. demonstrate that OsHSFA4d enhances thermotolerance by activating HSP101 and promoting CslF6 expression, which suppresses disease resistance. It is phosphorylated by OsCDPK24/28, increasing its DNA binding ability under heat stress. This trade-off mechanism of abiotic/biotic stress may broadly exist in plant kingdom.

Yu Fang
Haicheng Liao
Xuewei Chen
ResearchOpen Access14 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Exploration and validation of the prognostic value of mitophagy and mitochondrial dynamics-related genes in cervical cancer

Jiankui Li
Xi Chen
Juan Li
ResearchOpen Access10 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Impact of coal-to-gas transition on individual welfare considering the inverted U-shaped regulation effect of natural gas pipeline accessibility

Shi Jiankui
Xia Yingge
Hu Xiangdong
ResearchOpen Access17 Jul 2025
Scientific Reports

Volume: 15, P: 1-20
Large-area OLED substrate printing path planning method based on multi-head GAT imitation learning to solve partitioned integer programming

Jiacong Xiong
Jiankui Chen
Zhouping Yin
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

This paper describes the use of paired Cas9 nickases to edit the mammalian genome with no detectable off-target effects.

Bin Shen
Wensheng Zhang
William C Skarnes
Research02 Mar 2014
Nature Methods

Volume: 11, P: 399-402
Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell

Deng Luo
Meng Zhang
Jiankui He
ResearchOpen Access26 Jan 2018
Scientific Reports

Volume: 8, P: 1-9
A retrospective study of lymphatic transverse rectus abdominis myocutaneous/deep inferior epigastric perforator flaps for breast cancer treatment-induced upper-limb lymphoedema

Zhuangqing Yang
Sheng Huang
Dedian Chen
ResearchOpen Access06 Mar 2017
Scientific Reports

Volume: 7, P: 1-6
Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Xiaolong Wang
Honghao Yu
Yulin Chen
ResearchOpen Access10 Sept 2015
Scientific Reports

Volume: 5, P: 1-9
Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H₂O₂

Haicheng Liao
Yu Fang
Xuewei Chen
ResearchOpen Access14 Jan 2025
Cell Research

Volume: 35, P: 205-219
Preparation of high-resolution micro/nano dot array by electrohydrodynamic jet printing with enhanced uniformity

Yiwei Jin
Ziwei Zhao
Zhouping Yin
ResearchOpen Access23 Mar 2024
Scientific Reports

Volume: 14, P: 1-14
Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep

Xiaolong Wang
Yiyuan Niu
Yulin Chen
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-11
Quantitative assessment of single-cell whole genome amplification methods for detecting copy number variation using hippocampal neurons

Luwen Ning
Zhoufang Li
Jiankui He
ResearchOpen Access19 Jun 2015
Scientific Reports

Volume: 5, P: 1-13
A high-adaptability nozzle-array printing system based on a set covering printing planning model for printed display manufacturing

Yixin Wang
Jiankui Chen
Yiqun Li
ResearchOpen Access04 Jan 2023
Scientific Reports

Volume: 13, P: 1-15
Correction: Corrigendum: CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients

Shu Su
Bian Hu
Baorui Liu
Amendments and CorrectionsOpen Access19 Jan 2017
Scientific Reports

Volume: 7, P: 1
Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination

Yiqiang Cui
Yuyu Niu
Weizhi Ji
Correspondence12 Jan 2018
Cell Research

Volume: 28, P: 383-386
Comprehensive analysis of the T-cell receptor beta chain gene in rhesus monkey by high throughput sequencing

Zhoufang Li
Guangjie Liu
Jiankui He
ResearchOpen Access11 May 2015
Scientific Reports

Volume: 5, P: 1-11
An EAV-HP insertion in the promoter region of SLCO1B3 has pleiotropic effects on chicken liver metabolism based on the transcriptome and proteome analysis

Jianfei Chen
Guoying Hua
Xuemei Deng
ResearchOpen Access07 Apr 2021
Scientific Reports

Volume: 11, P: 1-13
Efficacy of Type 2 PRRSV vaccine against challenge with the Chinese lineage 1 (NADC30-like) PRRSVs in pigs

Chunhua Wei
Ailing Dai
Jiankui Liu
ResearchOpen Access25 Jul 2019
Scientific Reports

Volume: 9, P: 1-10
CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients

Shu Su
Bian Hu
Baorui Liu
ResearchOpen Access28 Jan 2016
Scientific Reports

Volume: 6, P: 1-14
Kallikrein-related peptidase 8 is expressed in myocardium and induces cardiac hypertrophy

Buqing Cao
Qing Yu
Xin Ni
ResearchOpen Access29 Jan 2016
Scientific Reports

Volume: 6, P: 1-17

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OsCDPK24 and OsCDPK28 phosphorylate heat shock factor OsHSFA4d to orchestrate abiotic and biotic stress responses in rice

Exploration and validation of the prognostic value of mitophagy and mitochondrial dynamics-related genes in cervical cancer

Impact of coal-to-gas transition on individual welfare considering the inverted U-shaped regulation effect of natural gas pipeline accessibility

Large-area OLED substrate printing path planning method based on multi-head GAT imitation learning to solve partitioned integer programming

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects

Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell

A retrospective study of lymphatic transverse rectus abdominis myocutaneous/deep inferior epigastric perforator flaps for breast cancer treatment-induced upper-limb lymphoedema

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H₂O₂

Preparation of high-resolution micro/nano dot array by electrohydrodynamic jet printing with enhanced uniformity

Multiplex gene editing via CRISPR/Cas9 exhibits desirable muscle hypertrophy without detectable off-target effects in sheep

Quantitative assessment of single-cell whole genome amplification methods for detecting copy number variation using hippocampal neurons

A high-adaptability nozzle-array printing system based on a set covering printing planning model for printed display manufacturing

Correction: Corrigendum: CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients

Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination

Comprehensive analysis of the T-cell receptor beta chain gene in rhesus monkey by high throughput sequencing

An EAV-HP insertion in the promoter region of SLCO1B3 has pleiotropic effects on chicken liver metabolism based on the transcriptome and proteome analysis

Efficacy of Type 2 PRRSV vaccine against challenge with the Chinese lineage 1 (NADC30-like) PRRSVs in pigs

CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients

Kallikrein-related peptidase 8 is expressed in myocardium and induces cardiac hypertrophy

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