Nature Search

Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses

Distinguishing benign renal masses from malignant renal tumours, and further differentiating indolent from aggressive renal cancers, on computed tomography (CT) scans remains challenging. Here, the authors develop deep learning models for distinguishing benign from malignant renal masses, and differentiating indolent from aggressive renal tumours in a large cohort of preoperative CT scans, obtaining high accuracy and a strong association with clinical outcomes.

Ying Xiong
Linpeng Yao
Shuo Wang
ResearchOpen Access07 Feb 2025
Nature Communications

Volume: 16, P: 1-14
Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Thomas Welte
Ik Sun Kim
Xiang H.-F. Zhang
Amendments and Corrections28 Jun 2016
Nature Cell Biology

Volume: 18, P: 822
Age specific clinical manifestations and vascular involvements in childhood-onset Takayasu arteritis

Yingjie Xu
Congying Wang
Xiaohui Li
Research24 Sept 2025
Pediatric Research

P: 1-8
Ferroelectricity with concomitant Coulomb screening in van der Waals heterostructures

Sliding ferroelectricity with finite conductance can yield ferroelectric hysteresis with concomitant Coulomb screening in monolayer graphene containing van der Waals heterostructures of various compositions.

Ruirui Niu
Zhuoxian Li
Jianming Lu
Research15 Jan 2025
Nature Nanotechnology

Volume: 20, P: 346-352
Author Correction: A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources

Bin Ma
Caiyu Lu
Jianming Xu
Amendments and CorrectionsOpen Access06 Dec 2023
Nature Communications

Volume: 14, P: 1
Cross-modal deep learning model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer

Jianming Guo
Baihui Chen
Dalin Li
ResearchOpen Access05 Sept 2024
npj Precision Oncology

Volume: 8, P: 1-13
Tumor suppressor p53 regulates intestinal type 2 immunity

P53 is a well-known tumour suppressor, however its role in intestinal type 2 immunity is currently unclear. Here authors report that during parasitic infections, p53 triggers tuft cell Ca²⁺ influx and IL-25 release, and shows a regulatory role for p53 in intestinal type 2 immunity via transcriptional regulation of the Lrmp gene.

Chun-Yuan Chang
Jianming Wang
Wenwei Hu
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-13
Conformational cycle of human polyamine transporter ATP13A2

ATP13A2 is a lysosomal polyamine transporter, mutated in several diseases including juvenile-onset Parkinson’s disease. Here, the authors report structures of human ATP13A2 in six distinct intermediate states, illustrating most of its conformational cycle.

Jianqiang Mu
Chenyang Xue
Zhongmin Liu
ResearchOpen Access08 Apr 2023
Nature Communications

Volume: 14, P: 1-12
Activating mutations in ALK provide a therapeutic target in neuroblastoma

This is one of four papers in this issue that identifies mutations in the tyrosine kinase receptor ALK in neuroblastoma, the most frequent childhood cancer. ALK is found to be a neuroblastoma predisposition gene and somatic points mutations were found in sporadic cases of neuroblastoma. These mutations lead the ALK kinase activation and are able to transform cells and display tumourigenic activity in vivo. ALK inhibitors decrease neuroblastoma cell proliferating and are potential anti-cancer drugs for the treatment of neuroblastoma.

Rani E. George
Takaomi Sanda
A. Thomas Look
Research16 Oct 2008
Nature

Volume: 455, P: 975-978
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice

Cancer cachexia is a systemic syndrome characterized by dramatic weight loss and decline in adipose tissue and skeletal muscle mass. Here, the authors show that overexpression of leukemia inhibitory factor (LIF), a secreted cytokine, suppresses de novo lipogenesis and induces cachexia in mice.

Xue Yang
Jianming Wang
Wenwei Hu
ResearchOpen Access20 Jan 2024
Nature Communications

Volume: 15, P: 1-15
Biogeographic patterns and drivers of soil viromes

Analysing biogeographic patterns in soil viromes based on 1,824 soil metagenomes from sites around the world, the authors show that viral diversity rarely corresponds to overall microbial diversity, with soil texture and moisture being closely associated with viral diversity.

Bin Ma
Yiling Wang
Jianming Xu
Research21 Feb 2024
Nature Ecology & Evolution

Volume: 8, P: 717-728
p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome

Radiation induced gastrointestinal syndrome is a complication of radiotherapy and the tumor suppressor p53 is implicated in protection from gastrointestinal toxicity. Here Wang and colleagues show that p53 protection against radiation-induced gastrointestinal syndrome involves intestinal stem cell function and inhibition of inflammation triggered by radiation via the IL12- p40/MHC-II axis.

Jianming Wang
Chun-Yuan Chang
Wenwei Hu
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-15
A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources

Soil conceals a vast realm of unexplored microbes, often referred to as the “microbial dark matter.” This hidden universe boasts a rich tapestry of microbial and genetic biodiversity. Here, the authors introduce the SMAG catalogue, comprising of 40,039 metagenome-assembled genomes from 3304 soil metagenomes, and uncovering 21,077 species-level genome bins.

Bin Ma
Caiyu Lu
Jianming Xu
ResearchOpen Access11 Nov 2023
Nature Communications

Volume: 14, P: 1-14
Molecular mechanisms of unique therapeutic potential of CUDC-907 for MEF2D fusion-driven BCP-ALL

Qing Xue
Ming Zhang
Sai-Juan Chen
ResearchOpen Access23 Jul 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-14
Multifunctional graphene heterogeneous nanochannel with voltage-tunable ion selectivity

Nanoporous 2D materials have shown promising potential for ion sieving applications due to their physical and chemical properties. Here authors develop a heterogeneous graphene-based polyethylene terephthalate nanochannel with ion sieving ability that is controlled by adjusting the applied voltage.

Shihao Su
Yifan Zhang
Jianming Xue
ResearchOpen Access19 Aug 2022
Nature Communications

Volume: 13, P: 1-10
Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases

Wei Guo
Bolun Zhou
Jie He
ResearchOpen Access01 Jan 2025
Experimental & Molecular Medicine

Volume: 57, P: 59-71
Disorder in M_n+1AX_n phases at the atomic scale

Highly ordered and compositionally complex ceramics are prone to disordering under irradiation, but exactly how is unclear. Here, the authors use high resolution microscopy to directly image the order-to-disorder phase transformations in Ti₃AlC₂ into otherwise unattainable solid solutions.

Chenxu Wang
Tengfei Yang
Yugang Wang
ResearchOpen Access07 Feb 2019
Nature Communications

Volume: 10, P: 1-9
High Sensitivity and Selectivity of AsP Sensor in Detecting SF₆ Decomposition Gases

Wang Jin
Yang Guofeng
Zheng Youdou
ResearchOpen Access13 Aug 2018
Scientific Reports

Volume: 8, P: 1-6
Mechanism of the Defect Formation in Supported Graphene by Energetic Heavy Ion Irradiation: the Substrate Effect

Weisen Li
Xinwei Wang
Jianming Xue
ResearchOpen Access30 Apr 2015
Scientific Reports

Volume: 5, P: 1-6
Regioselectivity and Mechanism of Synthesizing N-Substituted 2-Pyridones and 2-Substituted Pyridines via Metal-Free C-O and C-N Bond-Cleaving of Oxazoline[3,2-a]pyridiniums

Bo Li
Susu Xue
Weiliang Zhu
ResearchOpen Access25 Jan 2017
Scientific Reports

Volume: 7, P: 1-11
Dislocation-enhanced experimental-scale vacancy loop formation in hcp Zirconium in one single collision cascade

Wei Zhou
Jiting Tian
Shuming Peng
ResearchOpen Access12 Feb 2016
Scientific Reports

Volume: 6, P: 1-9
Evaluation of the new Chinese Disseminated Intravascular Coagulation Scoring System in critically ill patients: A multicenter prospective study

Yingying Wu
Lili Luo
Yu Hu
ResearchOpen Access22 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
Precipitation behavior of Al_xCoCrFeNi high entropy alloys under ion irradiation

Tengfei Yang
Songqin Xia
Yugang Wang
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-8
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Welte et al. report that mTOR signalling regulates G-CSF production and accumulation of myeloid-derived suppressor cells (MDSCs) to the tumour site, which promotes the tumour-initiating capacity of cancer cells by activating Notch signalling.

Thomas Welte
Ik Sun Kim
Xiang H.-F. Zhang
Research16 May 2016
Nature Cell Biology

Volume: 18, P: 632-644
Predictive factors for neoadjuvant combined immunotherapy in gastric adenocarcinoma: Focusing on the primitive enterocyte phenotype and PVR

Bingzhi Wang
Yinong Wang
Liyan Xue
Research08 May 2025
British Journal of Cancer

Volume: 133, P: 255-269
Dual-coupling-guided epitaxial growth of wafer-scale single-crystal WS₂ monolayer on vicinal a-plane sapphire

A dual-coupling-guided growth mechanism enables the realization of wafer-scale single-crystal WS₂ on vicinal a-plane sapphire.

Jinhuan Wang
Xiaozhi Xu
Kaihui Liu
Research15 Nov 2021
Nature Nanotechnology

Volume: 17, P: 33-38
Metastable alloying structures in MAPbI_3−xCl_x crystals

The characteristics of I/Cl alloying structures in MAPbI_3-xCl_x mixed-halide perovskites and their influences on the optoelectronic properties have been issues of long-standing controversy. In this work, by using on the time-dependent X-ray diffraction, ²⁰⁷Pb and ²H NMR, the authors investigated the I/Cl alloying structures and its long term stability in MAPbI_3-xCl_x (x = 0.0 to 0.3) single crystals. It was found that Cl can substitute for I of the PbI₃ inorganic lattice, leading to the tetragonal to cubic phase transition. Moreover, it revealed that the alloying structures of the MAPbI_3-xCl_x crystals are metastable and may decompose over time.

Wen-Cheng Qiao
Jianming Yang
Ye-Feng Yao
ResearchOpen Access16 Oct 2020
NPG Asia Materials

Volume: 12, P: 1-10
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche

The control of biophysical cues during the culture of human pluripotent stem cells on biomaterial substrates can be used to replicate the in vivo amniogenic environment and direct in vitro generation of early human amniotic tissue.

Yue Shao
Kenichiro Taniguchi
Jianping Fu
Research12 Dec 2016
Nature Materials

Volume: 16, P: 419-425
Molecular landscape and multi-omic measurements of heterogeneity in fetal adenocarcinoma of the lung

Li Sun
Wei Guo
Lin Lin
ResearchOpen Access03 Jun 2024
npj Precision Oncology

Volume: 8, P: 1-11
Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis

Xuetian Yue
Jianming Wang
Wenwei Hu
ResearchOpen Access19 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-12
Genomic features and tumor immune microenvironment alteration in NSCLC treated with neoadjuvant PD-1 blockade

Shuhang Wang
Pei Yuan
Jie He
ResearchOpen Access13 Jan 2022
npj Precision Oncology

Volume: 6, P: 1-8
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression

Zhenlong Chen
Rui Ren
Qiaoming Zhi
Research12 Jul 2019
Oncogene

Volume: 38, P: 6017-6034
Biodegradation of gentamicin by bacterial consortia AMQD4 in synthetic medium and raw gentamicin sewage

Yuanwang Liu
Huiqing Chang
Jianming Xue
ResearchOpen Access08 Sept 2017
Scientific Reports

Volume: 7, P: 1-11

Search

Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses

Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Age specific clinical manifestations and vascular involvements in childhood-onset Takayasu arteritis

Ferroelectricity with concomitant Coulomb screening in van der Waals heterostructures

Author Correction: A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources

Cross-modal deep learning model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer

Tumor suppressor p53 regulates intestinal type 2 immunity

Conformational cycle of human polyamine transporter ATP13A2

Activating mutations in ALK provide a therapeutic target in neuroblastoma

Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice

Biogeographic patterns and drivers of soil viromes

p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome

A genomic catalogue of soil microbiomes boosts mining of biodiversity and genetic resources

Molecular mechanisms of unique therapeutic potential of CUDC-907 for MEF2D fusion-driven BCP-ALL

Multifunctional graphene heterogeneous nanochannel with voltage-tunable ion selectivity

Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases

Disorder in M_n+1AX_n phases at the atomic scale

High Sensitivity and Selectivity of AsP Sensor in Detecting SF₆ Decomposition Gases

Mechanism of the Defect Formation in Supported Graphene by Energetic Heavy Ion Irradiation: the Substrate Effect

Regioselectivity and Mechanism of Synthesizing N-Substituted 2-Pyridones and 2-Substituted Pyridines via Metal-Free C-O and C-N Bond-Cleaving of Oxazoline[3,2-a]pyridiniums

Dislocation-enhanced experimental-scale vacancy loop formation in hcp Zirconium in one single collision cascade

Evaluation of the new Chinese Disseminated Intravascular Coagulation Scoring System in critically ill patients: A multicenter prospective study

Precipitation behavior of Al_xCoCrFeNi high entropy alloys under ion irradiation

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation

Predictive factors for neoadjuvant combined immunotherapy in gastric adenocarcinoma: Focusing on the primitive enterocyte phenotype and PVR

Dual-coupling-guided epitaxial growth of wafer-scale single-crystal WS₂ monolayer on vicinal a-plane sapphire

Metastable alloying structures in MAPbI_3−xCl_x crystals

Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche

Molecular landscape and multi-omic measurements of heterogeneity in fetal adenocarcinoma of the lung

Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis

Genomic features and tumor immune microenvironment alteration in NSCLC treated with neoadjuvant PD-1 blockade

Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression

Biodegradation of gentamicin by bacterial consortia AMQD4 in synthetic medium and raw gentamicin sewage

Search

Quick links

Search

Filter By:

Search

Quick links