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Showing 1–6 of 6 results
Advanced filters: Author: Jinchao Hou Clear advanced filters
  • Medical dressings are typically not effective at preventing bacteria invasion, and act only as a physical barrier. Here, defensin-conjugated polymer fabrics are shown to be effective against antibacterial activity for various drug-resistant bacteria, by preventing cell adhesion and biofilm formation, while encouraging wound healing.

    • Yaqi Sun
    • Hui Ye
    • Xiangming Fang
    ResearchOpen Access
    Communications Materials
    Volume: 6, P: 1-14
  • In non-small cell lung cancer, the presence of monocyte-derived macrophages inversely correlates with the presence of NK cells. Merad and colleagues propose that when monocytes phagocytose tumor debris they express TREM2, become pro-tumorigenic, and suppress NK cell recruitment and activation in tumors.

    • Matthew D. Park
    • Ivan Reyes-Torres
    • Miriam Merad
    Research
    Nature Immunology
    Volume: 24, P: 792-801
  • Tumor microenvironment elements can influence tumor state, including in skin basal cell carcinomas. Here the authors show that spatially organized and self-propagating TREM2+ tumor associated macrophages promote Ly6D- tumor cell proliferation via secretion of oncostatin M.

    • Daniel Haensel
    • Bence Daniel
    • Anthony E. Oro
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-22
  • Granular segregation may play a role in shaping the surface features of small celestial bodies such as asteroids that can be explained with the Brazil-nut effect. The authors study intruder dynamics in granular media on board the Chinese Space Station, finding that contrary to what occurs on Earth intruders tend to descend in microgravity conditions under specific vibration parameters

    • Ke Cheng
    • Meiying Hou
    • Mingcheng Yang
    ResearchOpen Access
    Communications Physics
    Volume: 7, P: 1-10
  • In humans, caspase-5 is an LPS sensor that can induce gasdermin D cleavage and pyroptosis. Here, the authors show that zebrafish caspy2 is a functional homolog as it also senses cytosolic LPS to activate the noncanonical inflammasome and to protect against bacterial infection, but it does so via pyrin death domain interactions.

    • Dahai Yang
    • Xin Zheng
    • Qin Liu
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12