The clinical outcomes of esophageal squamous cell carcinoma (ESCC) remain poor, and thus it remains critical to find prognostic molecular markers. Here, the authors identify prognostic ESCC subtypes based on bulk and single-cell RNA-seq combined with histology AI in samples from patients with more than four years of follow-up, and find markers associated with immune evasion.
- Guozhong Jiang
- Zhizhong Wang
- Yaohe Wang