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Showing 1–12 of 12 results
Advanced filters: Author: Jo Handelsman Clear advanced filters
  • Antibiotic resistance seriously threatens our ability to treat infectious diseases. The genes conferring resistance can easily move between organisms, resulting in nearly untreatable diseases. Jo Handelsman and colleagues describe how resistance is spread, the origin of the genes conferring this resistance and the roles they may have in their natural environments.

    • Heather K. Allen
    • Justin Donato
    • Jo Handelsman
    Reviews
    Nature Reviews Microbiology
    Volume: 8, P: 251-259
  • Metagenomics is an emerging and exciting new field that integrates biology and technology. Here, Jo Handelsman previews the selection of articles in this Focus issue.

    • Jo Handelsman
    Editorial
    Nature Reviews Microbiology
    Volume: 3, P: 457-458
  • Bacterial biofilms are aggregates of surface-associated cells embedded in an extracellular polysaccharide (EPS) matrix. Here, the authors describe a unique mode of collective movement by self-propelled, surface-associated spherical microcolonies with EPS cores in the gliding bacterium Flavobacterium johnsoniae.

    • Chao Li
    • Amanda Hurley
    • David J. Beebe
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12
  • In this Opinion article the authors propose that peptidoglycan is not only an essential structural component of the bacterial cell wall, but is also involved in diverse biological processes, such as microbial pathogenesis, symbiotic associations and a range of interactions between bacteria and other organisms.

    • Karen A. Cloud-Hansen
    • S. Brook Peterson
    • Jo Handelsman
    Reviews
    Nature Reviews Microbiology
    Volume: 4, P: 710-716
  • Qemistree uses fragmentation spectra to predict molecular fingerprints and represent their relationships as a tree, enabling comparison of metabolomics data across different experimental conditions and exploration of chemical diversity in mixtures.

    • Anupriya Tripathi
    • Yoshiki Vázquez-Baeza
    • Pieter C. Dorrestein
    Research
    Nature Chemical Biology
    Volume: 17, P: 146-151
  • An ingenious screening method exploiting substrate induction of gene expression provides a rapid means of identifying new catabolic pathways in unculturable microorganisms.

    • Jo Handelsman
    News & Views
    Nature Biotechnology
    Volume: 23, P: 38-39
  • As more type VI secretion systems are identified and the secreted effectors are studied, it is becoming clear that they have an important role in mediating interbacterial interactions. Although the focus has mainly been on antagonistic interactions, type VI secretion systems may have physiological roles that extend beyond antagonism. Mougous and colleagues review the microbial ecology of type VI secretion, including a potential role in modulating microbial community dynamics.

    • Alistair B. Russell
    • S. Brook Peterson
    • Joseph D. Mougous
    Reviews
    Nature Reviews Microbiology
    Volume: 12, P: 137-148