Nature Search

An integrative approach to identify novel miRNA-mRNA interaction networks in LMNA-cardiomyopathy

José Córdoba-Caballero
Fernando Bonet Martínez
Rocio Toro
ResearchOpen Access24 Jan 2026
Scientific Reports

Volume: 16, P: 1-18
Insulin resistance modulates gut microbiota and incretin response remodeling after bariatric surgery in severe obesity

Rocío Puig
M-Mar Rodríguez-Peña
Silvia Pellitero
Research10 Jan 2026
International Journal of Obesity

P: 1-11
Large-scale crossbar arrays based on three-terminal MoS₂ memtransistors

Three-terminal memtransistors can improve the neuromorphic performance of conventional two-terminal memristors. Here, the authors report the fabrication of high-yield large-scale crossbar array architectures incorporating up to 2,048 2D MoS₂ memtransistors per array, showing low-power memory and image recognition applications.

Thomas F. Schranghamer
Andrew Pannone
Saptarshi Das
ResearchOpen Access28 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Enhanced spatial clustering of single-molecule localizations with graph neural networks

Single-molecule localisation microscopy enables nanoscale mapping of molecular organisation, but clustering stochastic data remains challenging. Here, authors present a graph neural network method that enhances clustering across complex biological datasets.

Jesús Pineda
Sergi Masó-Orriols
Carlo Manzo
ResearchOpen Access03 Nov 2025
Nature Communications

Volume: 16, P: 1-17
An international Delphi consensus for reporting of setting in psychedelic clinical trials

A large international panel of experts reach consensus on a new standard for reporting settings in psychedelic trials, identifying 30 key non-pharmacological factors to strengthen the rigor of psychedelic research.

Chloé Pronovost-Morgan
Kyle T. Greenway
Keith Williams
ResearchOpen Access03 Jun 2025
Nature Medicine

Volume: 31, P: 2186-2195
Translational strategies in aging and age-related disease

Six leaders in aging research discuss how to translate their findings in the field.

Mary Armanios
Rafael de Cabo
Saul Villeda
Comments & Opinion08 Dec 2015
Nature Medicine

Volume: 21, P: 1395-1399
Fluorescently excited CO emission in the 49 Ceti debris disk spatially resolved by JWST/NIRSpec

JWST/NIRSpec observations of the 49 Ceti debris disk reveal spatially resolved, fluorescently excited CO emission, indicating a secondary origin of the gas in debris disks (that is, from the collision of volatile-rich bodies).

Kadin Worthen
Christine H. Chen
Elodie Choquet
Research23 Sept 2025
Nature Astronomy

Volume: 9, P: 1680-1691
Differential responses in the fusiform region to same-race and other-race faces

Alexandra J. Golby
John D. E. Gabrieli
Jennifer L. Eberhardt
Research01 Aug 2001
Nature Neuroscience

Volume: 4, P: 845-850
Reducing the carbon footprint of chemistry labs

Philippe Loubet and André Estévez-Torres, from Bordeaux INP and CNRS-University of Lille respectively, talk to Nature Chemistry about assessing the carbon footprint of chemistry laboratories, and approaches to reducing their environmental impact.

Joan Serrano-Plana
Comments & Opinion03 Nov 2025
Nature Chemistry

Volume: 17, P: 1624-1625
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Although mutant H3K27M histones inhibit PRC2 in diffuse intrinsic pontine gliomas, these tumors exhibit significant amounts of PRC2 activity. The repression of several genes, including INK4A, by residual EZH2 activity is required for tumor growth, and EZH2 inhibitors therefore represent potential therapies for these patients.

Faizaan Mohammad
Simon Weissmann
Kristian Helin
Research27 Feb 2017
Nature Medicine

Volume: 23, P: 483-492
The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models

Oncolytic virus holds potential as a cancer therapy, but further optimization is desirable. Here the authors screen existing drug to find talazoparib, a PARP inhibitor, synergizing with reovirus type 3 Dearing (RT3D) to induce cancer cell apoptosis, anti-tumor immunity, as well as control of primary and rechallenge tumor in mouse models.

Joan Kyula-Currie
Victoria Roulstone
Kevin J. Harrington
ResearchOpen Access08 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions

Early experiences shape cognition. Here, authors show that early environmental enrichment or deprivation alters cognition in mice, linked to gene expression and chromatin changes in hippocampal excitatory neurons, with AP-1 as a key regulator.

Marta Alaiz-Noya
Federico Miozzo
Angel Barco
ResearchOpen Access05 Nov 2025
Nature Communications

Volume: 16, P: 1-21
The reuse of genetic information in research and informed consent

David Lorenzo
Montse Esquerda
Francesc Palau
Research13 Sept 2023
European Journal of Human Genetics

Volume: 31, P: 1393-1397
Synthesised database of wild bee and hoverfly records in Europe

Ahlam Sentil
Marija Miličić
Natasha de Manincor
ResearchOpen Access30 Jan 2026
Scientific Data

Volume: 13, P: 1-20
SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence

Using mouse pancreatic cancer models, Tsanov et al. show that reactivation of SMAD4 at metastatic sites promotes tumor growth in the lung through RUNX1 but restrains metastatic growth through KLF4 in the liver, influenced by organ-specific epigenetic states.

Kaloyan M. Tsanov
Francisco M. Barriga
Scott W. Lowe
ResearchOpen Access25 Sept 2025
Nature Cancer

Volume: 6, P: 1839-1856
Genome-wide analyses identify 30 loci associated with obsessive–compulsive disorder

Genome-wide analyses identify 30 independent loci associated with obsessive–compulsive disorder, highlighting genetic overlap with other psychiatric disorders and implicating putative effector genes and cell types contributing to its etiology.

Nora I. Strom
Zachary F. Gerring
Manuel Mattheisen
ResearchOpen Access13 May 2025
Nature Genetics

Volume: 57, P: 1389-1401
Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Genome-wide association meta-analyses of attention-deficit/hyperactivity disorder symptom measures and clinical diagnoses identify new risk loci, highlight putative effector genes and yield improved polygenic risk scores.

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Research17 Sept 2025
Nature Genetics

Volume: 57, P: 2427-2435
Rapid interhemispheric climate links via the Australasian monsoon during the last deglaciation

The global monsoon is considered to have provided an important interhemispheric climate link during deglaciation, but direct evidence is lacking. Here, climate evidence from speleothems suggests that rapid latitudinal displacements of the Australasian monsoon play a key role in deglacial warming.

Linda K. Ayliffe
Michael K. Gagan
Bambang W. Suwargadi
Research06 Dec 2013
Nature Communications

Volume: 4, P: 1-6
Depositional Histories of Sand Grains from Surface Textures (reply)

JOAN E. BROWN
Research07 Sept 1973
Nature

Volume: 245, P: 31-32
Why media relations matter

There is a common misperception that only medium- and large-cap biotechs need to understand and interact with the media. As investor demands increase and partnering dynamics evolve, startups need to understand the art of media relations more now than ever before.

Joan E Kureczka
Comments & Opinion20 Mar 2006
Nature Biotechnology

Volume: 24, P: 387-389
How people wake up is associated with previous night’s sleep together with physical activity and food intake

In a prospective longitudinal study of 833 adults, we demonstrate that how you wake up and regain alertness in the hours after sleep is weakly associated with your genes. Instead, the modifiable factors of how you are sleeping, eating and exercising influence your return to full alertness, free of sleepiness.

Raphael Vallat
Sarah E. Berry
Matthew P. Walker
ResearchOpen Access19 Nov 2022
Nature Communications

Volume: 13, P: 1-15
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination

Intravital imaging reveals macrophage-driven de novo induction of cancer stem cells in vivo, and their dramatic enrichment on dissemination through TMEM doorways. These findings provide a mechanism for the validated ability of TMEM doorway density to be prognostic for distant recurrence of metastatic tumors in breast cancer patients.

Ved P. Sharma
Binwu Tang
Maja H. Oktay
ResearchOpen Access15 Dec 2021
Nature Communications

Volume: 12, P: 1-24
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk

G49, a dual glucagon/glucagon-like peptide-1 receptor agonist, triggers an inter-organ crosstalk between adipose tissue, pancreas and liver, leading to brown fat activation with the final outcomes of increased energy expenditure and body weight loss.

M. Pilar Valdecantos
Laura Ruiz
Ángela M. Valverde
ResearchOpen Access28 Nov 2024
Nature Communications

Volume: 15, P: 1-29
BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells

Here, the authors find that BMAL1, best known for controlling the body clock, partners with TRIM28 in naïve pluripotent stem cells to repress retrotransposons.

Amador Gallardo
Efres Belmonte-Reche
David Landeira
ResearchOpen Access10 Sept 2025
Nature Communications

Volume: 16, P: 1-15
Evolutionarily distinct lineages of a migratory bird of prey show divergent responses to climate change

Understanding species’ spatiotemporal dynamics is key to predicting their responses to climate change. Here, the authors combine landscape genomics, demographic reconstructions, and species distribution models to assess lineage-specific responses to past and future climate in a migratory raptor.

Joan Ferrer Obiol
Anastasios Bounas
Diego Rubolini
ResearchOpen Access13 Apr 2025
Nature Communications

Volume: 16, P: 1-16
Mu rhythm motor–auditory delay in imagined speech mirrors overt speech timing

Francesco Mantegna
David Poeppel
Joan Orpella
ResearchOpen Access28 Jan 2026
Scientific Reports

Volume: 16, P: 1-14
Widespread horse-based mobility arose around 2200 bce in Eurasia

Analyses of 475 ancient horse genomes show modern horses emerged around 2200 bce, coinciding with sudden expansion across Eurasia, refuting the narrative of large horse herds accompanying earlier migrations of steppe peoples across Europe.

Pablo Librado
Gaetan Tressières
Ludovic Orlando
ResearchOpen Access06 Jun 2024
Nature

Volume: 631, P: 819-825
The MBCRC Advocate Researcher Program (MARP): connecting advocates and researchers as collaborative partners in cancer research

Hillary S. Andrews
Igor L. Bado
Josh Newby
ResearchOpen Access21 Jun 2025
npj Breast Cancer

Volume: 11, P: 1-5
Tethered neoantigens from the dead sculpt tumor fate

New data show that DNGR-1 enables type 1 conventional dendritic cells to sculpt cancer immunoediting through selective cross-presentation of F-actin-tethered neoantigens, enriching tumors for immune-evasive variants.

J. Magarian Blander
Atimukta Jha
News & Views02 Jan 2026
Nature Immunology

Volume: 27, P: 7-9
A natural biological control of Dutch elm disease

Joan Webber
Research30 Jul 1981
Nature

Volume: 292, P: 449-451
Reviews of Nuclear Physics

JOAN M. FREEMAN
Research01 Apr 1961
Nature

Volume: 190, P: 62-63
Multi-view deep learning framework for the detection of chest X-rays compatible with pediatric pulmonary tuberculosis

In this work, authors present an AI framework to detect pediatric tuberculosis by using both frontal and lateral chest X-rays, showing robust performance across several age groups and settings.

Daniel Capellán-Martín
Juan J. Gómez-Valverde
María J. Ledesma-Carbayo
ResearchOpen Access27 Oct 2025
Nature Communications

Volume: 16, P: 1-16
The relative deficit of GDF15 in adolescent girls with PCOS can be changed into an abundance that reduces liver fat

Francis de Zegher
Marta Díaz
Lourdes Ibáñez
ResearchOpen Access29 Mar 2021
Scientific Reports

Volume: 11, P: 1-6
Tegavivint triggers TECR-dependent nonapoptotic cancer cell death

In chemical-genetic and lipidomics analyses, the clinical candidate oncology drug tegavivint induced an unconventional form of nonapoptotic cell death that required the lipid metabolic enzyme trans-2,3-enoyl-CoA reductase.

Logan Leak
Ziwei Wang
Scott J. Dixon
Research26 May 2025
Nature Chemical Biology

Volume: 21, P: 1873-1884
Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α

p38α is a kinase that regulates many cellular processes. Here authors report that redox fluctuations induce conformational changes to fine-tune the p38α activity beyond its activation loop phosphorylation.

Joan Pous
Blazej Baginski
Maria J. Macias
ResearchOpen Access01 Dec 2023
Nature Communications

Volume: 14, P: 1-11
Engineering tumors with 3D scaffolds

Claudia Fischbach
Ruth Chen
David J Mooney
Research02 Sept 2007
Nature Methods

Volume: 4, P: 855-860
Structural analysis of the yeast SWI/SNF chromatin remodeling complex

Corey L. Smith
Rachel Horowitz-Scherer
Craig L. Peterson
Research13 Jan 2003
Nature Structural Biology

Volume: 10, P: 141-145
Gender differences in HIV-1 diversity at time of infection

E. Michelle Long
Harold L. Martin Jr.
Julie Overbaugh
Research01 Jan 2000
Nature Medicine

Volume: 6, P: 71-75
Exploring biases related to the use of large language models in a multilingual depression corpus

Paula Andrea Perez-Toro
Judith Dineley
Nicholas Cummins
ResearchOpen Access16 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
Characterising the asynchronous resurgence of common respiratory viruses following the COVID-19 pandemic

COVID-19-related non-pharmaceutical interventions impacted the circulation of other pathogens. Here, the authors compile a global viral activity dataset and compare the timing of resurgence of seven common respiratory viruses following the relaxation of interventions across different geographical regions.

Chenkai Zhao
Tiantian Zhang
Marie N. Billard
ResearchOpen Access13 Feb 2025
Nature Communications

Volume: 16, P: 1-11
Are snRNPs involved in splicing?

Michael R. Lerner
John A. Boyle
Joan A. Steitz
Research10 Jan 1980
Nature

Volume: 283, P: 220-224
Excised DNA circles from V(D)J recombination promote relapsed leukaemia

Excised signal circles are circular DNA by-products of V(D)J recombination that form a complex with the V(D)J recombinase, and when increased in abundance, result in increased mutagenesis, causing adverse outcomes in cancer.

Zeqian Gao
James N. F. Scott
Joan Boyes
ResearchOpen Access06 Aug 2025
Nature

Volume: 645, P: 774-783
Greening mitigates heat-related mortality in Paris

Hicham Achebak
Pierre Masselot
Grégoire Rey
ResearchOpen Access27 Jan 2026
npj Urban Sustainability

Volume: 6, P: 1-6
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen

Theodore S. Jardetzky
Jerry H. Brown
Don C. Wiley
Research21 Apr 1994
Nature

Volume: 368, P: 711-718
Vaccines stop diseases safely — why all the suspicion?

To immunize people against misinformation, public-health researchers must forge authentic relationships that build confidence, urges Heidi Larson. By Joan Donovan

Joan Donovan
Books & Arts22 Jul 2020
Nature

Volume: 583, P: 680-681
SNAP-47 mediates somatic oxytocin dynamics in hypothalamic neurons

SNAP-47 drives somatic oxytocin trafficking in hypothalamic neurons. Its loss disrupts OT release, alters synaptic activity, and impairs sociability, uncovering a molecular pathway linking OT dynamics to social behavior.

Beatriz Aznar-Escolano
Maria Royo
Sandra Jurado
ResearchOpen Access02 Feb 2026
Communications Biology

Volume: 9, P: 1-15
Effect of Iron and Zinc on Nucleic Acid and Protein Synthesis in Mycobacterium smegmatis

FRANK WINDER
JOAN M. DENNENY
Research29 Aug 1959
Nature

Volume: 184, P: 742-743
Data harmonization for the analysis of personalized treatment of psychosis with metacognitive training

Caroline König
Pedro Copado
Susana Ochoa
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
Vitamin C from Green Tomatoes

FRANK WOKES
JOAN G. ORGAN
Research31 Oct 1942
Nature

Volume: 150, P: 523-524
Differences in Uridine Diphosphate Galactose-4-Epimerase between Haemolysates of Newborns and of Adults

WON G. NG
GEORGE N. DONNELL
WILLIAM R. BERGREN
Research15 Apr 1967
Nature

Volume: 214, P: 283-284

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