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Showing 1–3 of 3 results

Advanced filters: Author: Jonathan Zöller Clear advanced filters

P-type ATPase magnesium transporter MgtA acts as a dimer

Zeinert et al. provide cryo-EM structures of the E. coli Mg²⁺ importer MgtA: unexpectedly, this P-type ATPase is a dimer with an uncommon transmembrane ion-binding site and knotted N-terminus, which are functionally important features.

Rilee Zeinert
Fei Zhou
Doreen Matthies
Research23 Jun 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1633-1643
Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA

Elevator transporters, like SLC23 proteins, transport solutes by a mechanism involving a reorientation of two rigid domains. Here, the authors show that linkers connecting these domains control the carrier’s conformational space and thus its function.

Benedikt T. Kuhn
Jonathan Zöller
Eric R. Geertsma
ResearchOpen Access30 Aug 2024
Nature Communications

Volume: 15, P: 1-12
Cardiovascular disease in neurofibromatosis 1: Report of the NF1 Cardiovascular Task Force

J M Friedman
Jack Arbiser
Bruce R Korf
Reviews01 May 2002
Genetics in Medicine

Volume: 4, P: 105-111