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Advanced filters: Author: Juan Alcain Clear advanced filters

Pre-TCR-targeted immunotherapy for T cell acute lymphoblastic leukemia

The authors identify pre-TCR as a key biomarker and therapeutic target in T-ALL. Targeting it with an anti-pTα antibody–drug conjugate inhibits leukemia-initiating cells and tumor growth in mice, offering promise for relapsed/refractory T-ALL treatment.

Patricia Fuentes
Marina García-Peydró
María L. Toribio
ResearchOpen Access01 Sept 2025
Nature Immunology

Volume: 26, P: 1712-1725
Mesenteric adipose tissue in Crohn’s disease alters the immune response of the ileal mucosa and increases angiogenesis and fibrosis

Flores Martín-Reyes
Imane Kentaoui-Bousellam
Cristina Rodriguez-Diaz
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Selective induction of apoptosis by capsaicin in transformed cells: the role of reactive oxygen species and calcium

Antonio Macho
Marco A Calzado
Eduardo Muñoz
Research28 Jan 1999
Cell Death & Differentiation

Volume: 6, P: 155-165
Evaluation of therapeutic targeting of CCR7 in acute graft-versus-host disease

Carlos Cuesta-Mateos
Itxaso Portero-Sainz
Cecilia Muñoz-Calleja
Research21 Feb 2020
Bone Marrow Transplantation

Volume: 55, P: 1935-1945
The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance

Carolina Gutierrez-Repiso
Francisca Rodriguez-Pacheco
Eduardo Garcia-Fuentes
Research14 Sept 2015
Laboratory Investigation

Volume: 95, P: 1409-1417