Camacho et al. show detection of non-aggregated and aggregated α-synuclein in brain tissue from a mouse model of Parkinson’s disease using 2-dimensional polarization imaging. This fluorescence imaging method will allow for early detection of pathogenic α-synuclein aggregates associated with neurodegenerative illnesses.
- Rafael Camacho
- Daniela Täuber
- Ivan G. Scheblykin