A novel GelMA/ECM hydrogel fibrous scaffold was constructed via electrospinning and decellularization technique. The GelMA/ECM scaffold characterized by excellent mechanical properties and biocompatibility, can accelerate SCI repair by recruiting and promoting the differentiation of neural stem cells (NSCs), and reducing the proportion of M1-type macrophages. The study provides a promising system for SCI repair in clinical application.
- Zheng Chen
- Lin Wang
- Qin Shi