Nature Search

Soft bioelectronics embedded with self-confined tetrahedral DNA circuit for high-fidelity chronic wound monitoring

Wound biomarker monitoring faces challenges in both sensitivity and stability. Here, authors present soft wireless bioelectronic device, using self-confined tetrahedral DNA circuits, that enhance detection limits, resists biofouling, and enables stable and real-time monitoring of diabetic wound healing.

Xiao Zhao
Jiahao Huang
Lianhui Wang
ResearchOpen Access07 Oct 2025
Nature Communications

Volume: 16, P: 1-15
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

HRD1 is an E3 ligase known to play a role in targeting degradation of misfolded proteins in the ER. Here the authors show that HRD1 interacts with metabolic enzymes and its liver specific deficiency results in lower body weight, blood glucose and plasma lipids during high fat diet in mice.

Juncheng Wei
Yanzhi Yuan
Deyu Fang
ResearchOpen Access10 Sept 2018
Nature Communications

Volume: 9, P: 1-14
A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations

Hongbing Shen, Zuomin Zhou, Yijiang Chen, Zhibin Hu and colleagues report genome-wide association analyses of sporadic non-syndromic congenital heart malformations in Han Chinese populations and identify two risk loci at 1p12 and 4q31.

Zhibin Hu
Yongyong Shi
Hongbing Shen
Research26 May 2013
Nature Genetics

Volume: 45, P: 818-821
Re-convolving the compositional landscape of primary and recurrent glioblastoma reveals prognostic and targetable tissue states

Glioblastoma (GBM) cells can infiltrate into the tumour microenvironment (TME) and contribute to recurrence. Here, the authors analyse primary and recurrent GBMs and their TME using single-nucleus and spatial transcriptomics, revealing tissue states defined by the combinations of neoplastic and non-neoplastic cells, which could be therapeutic targets.

Osama Al-Dalahmah
Michael G. Argenziano
Peter Canoll
ResearchOpen Access04 May 2023
Nature Communications

Volume: 14, P: 1-18
A pangenome reference of 36 Chinese populations

A study reports data from the first phase of the Chinese Pangenome Consortium including 116 de novo assemblies from 58 core samples representing 36 minority Chinese ethnic groups.

Yang Gao
Xiaofei Yang
Shuhua Xu
ResearchOpen Access14 Jun 2023
Nature

Volume: 619, P: 112-121
Structural insights into drug transport by an aquaglyceroporin

Pentamidine and melarsoprol are drugs used to treat sleeping sickness caused by Trypanosoma brucei. Here, authors present cryo-EM structures of TbAQP2 with molecular dynamic simulations, revealing mechanisms shaping substrate specificity and drug permeation.

Wanbiao Chen
Rongfeng Zou
Chongyuan Wang
ResearchOpen Access11 May 2024
Nature Communications

Volume: 15, P: 1-10
Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

The basis for associations between lung cancer and major histocompatibility complex genes is not completely understood. Here the authors further consider genetic variation within the MHC region in lung cancer patients and identify independent associations within HLA genes that explain MHC lung cancer associations in Europeans and Asian populations.

Aida Ferreiro-Iglesias
Corina Lesseur
Paul Brennan
ResearchOpen Access25 Sept 2018
Nature Communications

Volume: 9, P: 1-12
Embracing the digital landscape: enriching the concept of sense of place in the digital age

Juncheng Dai
Fangyu Liu
ResearchOpen Access03 Jun 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-7
Association analysis identifies new risk loci for non-obstructive azoospermia in Chinese men

Non-obstructive azoospermia (NOA) is a major cause of male infertility. Here, the authors provide insight into the genetic basis of NOA by identifying three new genetic risk loci in a genome-wide association study and reporting a fourth potential NOA susceptibility locus based on a Drosophilaknockdown experiment.

Zhibin Hu
Zheng Li
Jiahao Sha
Research23 May 2014
Nature Communications

Volume: 5, P: 1-7
Computational study of diffraction image formation from XFEL irradiated single ribosome molecule

Michal Stransky
Juncheng E
Adrian P. Mancuso
ResearchOpen Access09 May 2024
Scientific Reports

Volume: 14, P: 1-8
PIK3CA mutations are associated with pathologic complete response rate to neoadjuvant pyrotinib and trastuzumab plus chemotherapy for HER2-positive breast cancer

Qiyun Shi
Juncheng Xuhong
Jun Jiang
ResearchOpen Access02 Nov 2022
British Journal of Cancer

Volume: 128, P: 121-129
Cooperation between SIX1 and DHX9 transcriptionally regulates integrin-focal adhesion signaling mediated metastasis and sunitinib resistance in KIRC

Shiyu Huang
Juncheng Hu
Lei Wang
Research22 Aug 2024
Oncogene

Volume: 43, P: 2951-2969
Can digital finance curb corporate ESG decoupling? Evidence from Shanghai and Shenzhen A-shares listed companies

Hua Liu
Juncheng Wang
Mengna Liu
ResearchOpen Access26 Nov 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-15
Water layer and radiation damage effects on the orientation recovery of proteins in single-particle imaging at an X-ray free-electron laser

Juncheng E
Michal Stransky
Adrian P. Mancuso
ResearchOpen Access29 Sept 2023
Scientific Reports

Volume: 13, P: 1-11
Effects of radiation damage and inelastic scattering on single-particle imaging of hydrated proteins with an X-ray Free-Electron Laser

Juncheng E
Michal Stransky
Adrian P. Mancuso
ResearchOpen Access09 Sept 2021
Scientific Reports

Volume: 11, P: 1-11
Paradoxical implication of BAX/BAK in the persistence of tetraploid cells

Jiayin Deng
Lucía G. Gutiérrez
Laura Senovilla
ResearchOpen Access01 Nov 2021
Cell Death & Disease

Volume: 12, P: 1-13

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