This article reviews the known cases of aromatase deficiency, which causes virilization of affected female fetuses and their mothers. In girls the deficiency causes pseudohermaphroditism at birth, and a lack of transition through puberty. Males are generally diagnosed later in life. This condition shows important roles for estrogen in metabolism of many systems other than reproduction.
- Margaret EE Jones
- Wah Chin Boon
- Evan R Simpson
