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Showing 1–50 of 89 results

Advanced filters: Author: K. Iizuka Clear advanced filters

Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na⁺, K⁺-ATPase

N lizuka
K Miyamoto
M Oka
ResearchOpen Access10 Oct 2000
British Journal of Cancer

Volume: 83, P: 1209-1215
Late fluid flow in a primitive asteroid revealed by Lu–Hf isotopes in Ryugu

Analysis of samples from the asteroid Ryugu provide evidence of late fluid flow in a carbonaceous asteroid, indicating that such bodies may have retained two to three times more water than previously thought.

Tsuyoshi Iizuka
Takazo Shibuya
Hisayoshi Yurimoto
Research10 Sept 2025
Nature

Volume: 646, P: 62-67
Circulating cell-free DNA as a predictive marker for distant metastasis of hepatitis C virus-related hepatocellular carcinoma

Y Tokuhisa
N Iizuka
M Oka
ResearchOpen Access16 Oct 2007
British Journal of Cancer

Volume: 97, P: 1399-1403
The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma

N Iizuka
K Hirose
M Oka
ResearchOpen Access10 Sept 1999
British Journal of Cancer

Volume: 81, P: 469-475
Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

Genome-wide association analyses in the Japanese population and trans-ancestry meta-analyses identify new risk loci for coronary artery disease. A polygenic risk score derived from these findings identifies individuals with increased risk of long-term cardiovascular mortality.

Satoshi Koyama
Kaoru Ito
Issei Komuro
Research05 Oct 2020
Nature Genetics

Volume: 52, P: 1169-1177
Sexual maturation of Japanese eel and production of eel larvae in the aquarium

K. YAMAMOTO
K. YAMAUCHI
Research20 Sept 1974
Nature

Volume: 251, P: 220-222
Efficacy and safety of givosiran in Japanese patients with acute hepatic porphyria: clinical findings from an expanded access study

Nobuaki Ozaki
Yoshie Goto
Tomohide Adachi
ResearchOpen Access02 May 2025
Scientific Reports

Volume: 15, P: 1-10
Functional localization of a melanoma tumor suppressor gene to a small (≤2 Mb) region on 11q23

Gavin P Robertson
Eleonora K Goldberg
Jane W Fountain
Research25 May 1999
Oncogene

Volume: 18, P: 3173-3180
Pauli spin blockade at room temperature in double-quantum-dot tunneling through individual deep dopants in silicon

Pauli spin blockade (PSB) is a spin-dependent charge transport process that typically appears in double quantum dot (QD) devices and is employed in fundamental research on single spins in nanostructures. Herein, the authors confirm that a single deep dopant in the silicon transistor functions as a room-temperature QD; consequently, transport through two different deep dopants exhibits PSB up to room temperature

Yoshisuke Ban
Kimihiko Kato
Keiji Ono
ResearchOpen Access23 Jul 2025
Communications Physics

Volume: 8, P: 1-7
Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

A comparison of copper and zinc isotopic measurements between the Ryugu samples and various carbonaceous chondrites excludes any genetic link between the two except for the CI (Ivuna-type) chondrites. Ryugu-like material might have accounted for ~5% of Earth’s mass.

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Research12 Dec 2022
Nature Astronomy

Volume: 7, P: 182-189
Selective intrathecal phenol block to improve activities of daily living in patients with spastic quadriplegia. A preliminary report

E Iwatsubo
E Okada
T Akatsu
Research01 Jul 1994
Spinal Cord

Volume: 32, P: 489-492
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk loci and mapping effects across multiple ethnicities.

Puya Gharahkhani
Eric Jorgenson
Janey L. Wiggs
ResearchOpen Access24 Feb 2021
Nature Communications

Volume: 12, P: 1-16
Carbonate record of temporal change in oxygen fugacity and gaseous species in asteroid Ryugu

The asteroid Ryugu experienced aqueous alteration under changing temperature and redox conditions, according to an isotopic analysis of secondary calcite and dolomite grains in samples from Ryugu obtained by the Hayabusa2 spacecraft.

Wataru Fujiya
Noriyuki Kawasaki
Hisayoshi Yurimoto
Research10 Jul 2023
Nature Geoscience

Volume: 16, P: 675-682
Crystal and Magnetic Structures of Double Hexagonal Close-Packed Iron Deuteride

Hiroyuki Saitoh
Akihiko Machida
Katsutoshi Aoki
ResearchOpen Access18 Jun 2020
Scientific Reports

Volume: 10, P: 1-8
Near-field spectroscopic investigation of dual-band heavy fermion metamaterials

Understanding the electromagnetic responses at subwavelength scales is important for achieving tunability. Using a combination of the near-field and far-field spectroscopy, the authors demonstrate a heavy fermion metamaterial with tunable dual-band optical responses by selectively and separately modifying the 4f and 5d band electrons.

Stephanie N. Gilbert Corder
Xinzhong Chen
Mengkun Liu
ResearchOpen Access22 Dec 2017
Nature Communications

Volume: 8, P: 1-7
Anterior dislocation and extruded disc of the lower cervical spine

K Shiba
WS EL-Masry
CH Tator
Research09 Aug 1999
Spinal Cord

Volume: 37, P: 538-541
Reduced marine phytoplankton sulphur emissions in the Southern Ocean during the past seven glacials

Ice core derived marine biogenic sulphate does not agree with marine sediment records. Here based on new ice core records spanning the past 720,000 years obtained from Dome Fuji the authors propose that dust contributed a higher percentage of sulphate aerosols than previously thought.

K. Goto-Azuma
M. Hirabayashi
Y. Fujii
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-7
A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13–15, a region subject to LOH and rearrangement in human carcinoma cell lines

Jiong Zhou
Annie YN Ng
Ismail Kola
Research24 Nov 1998
Oncogene

Volume: 17, P: 2719-2732
A cross-population atlas of genetic associations for 220 human phenotypes

Genome-wide analyses in BioBank Japan, UK Biobank and FinnGen identify ~5,000 new loci associated with 220 human traits. Statistical decomposition of matrices of phenome-wide summary statistics further highlights variants underpinning diseases across populations.

Saori Sakaue
Masahiro Kanai
Yukinori Okada
Research30 Sept 2021
Nature Genetics

Volume: 53, P: 1415-1424
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

Masato Kasuga and colleagues and Shiro Maeda and colleagues each report the independent identification of SNPs in KCNQ1 associated with type 2 diabetes in the Japanese population. Each group replicated the associations in other populations of East Asian and European descent.

Hiroyuki Unoki
Atsushi Takahashi
Shiro Maeda
Research17 Aug 2008
Nature Genetics

Volume: 40, P: 1098-1102
Greenland records of aerosol source and atmospheric lifetime changes from the Eemian to the Holocene

Past climate changes in Greenland ice were accompanied by large aerosol concentration changes. Here, the authors show that by correcting for transport effects, reliable source changes for biogenic aerosol from North America, sea salt aerosol from the North Atlantic, and dust from East Asian deserts can be derived.

S. Schüpbach
H. Fischer
E. W. Wolff
ResearchOpen Access16 Apr 2018
Nature Communications

Volume: 9, P: 1-10
Reply: CIITA methylation and decreased levels of HLA-DR in tumour progression

Y Morimoto
M Toyota
K Imai
CorrespondenceOpen Access27 Jul 2004
British Journal of Cancer

Volume: 91, P: 814-815
On-chip quantum interference between silicon photon-pair sources

A silicon-on-insulator device combining two four-wave-mixing photon-pair sources in an interferometer with a reconfigurable phase shifter is used to create and manipulate non-degenerate or degenerate, path-entangled or path-unentangled photon pairs. A quantum interference visibility of nearly 100% is observed on-chip. This device is a first step towards fully integrated quantum technologies.

J. W. Silverstone
D. Bonneau
M. G. Thompson
Research15 Dec 2013
Nature Photonics

Volume: 8, P: 104-108
Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

Finding causal variants and genes from GWAS loci results remains a challenge. Here, the authors train a model to predict if a variant affects nearby gene expression, and apply the method to identify new possible causal eQTLs and mechanisms of GWAS loci.

Qingbo S. Wang
David R. Kelley
Hilary K. Finucane
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-11
Tumour cells engineered to secrete interleukin-15 augment anti-tumour immune responses in vivo

S Hazama
T Noma
M Oka
ResearchOpen Access11 Jun 1999
British Journal of Cancer

Volume: 80, P: 1420-1426
Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores

PolyPred and PolyPred⁺ methods that leverage fine-mapping and non-European training data significantly improve cross-population polygenic prediction accuracy when applied to diseases and complex traits in UK Biobank populations.

Omer Weissbrod
Masahiro Kanai
Alkes L. Price
Research07 Apr 2022
Nature Genetics

Volume: 54, P: 450-458
A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS

The zinc-finger transcription factor IKAROS is essential for B cell development. Taniuchi, Morio and colleagues identify a human kindred presenting with B cell immunodeficiency that was caused by a heterozygous missense mutation in IKZF3 encoding the related AIOLOS protein. AIOLOS^G159R is a mutant protein that interferes with both wild-type AIOLOS and IKAROS by forming heterodimers that bind to aberrant DNA-binding sites and prevent normal expression of IKAROS-dependent genes.

Motoi Yamashita
Hye Sun Kuehn
Tomohiro Morio
Research21 Jun 2021
Nature Immunology

Volume: 22, P: 893-903
Eemian interglacial reconstructed from a Greenland folded ice core

Reconstruction of the Eemian interglacial from the new NEEM ice core shows that in spite of a climate warmer by eight degrees Celsius in Northern Greenland than that of the past millennium, the ice here was only a few hundred metres lower than its present level.

D. Dahl-Jensen
M. R. Albert
J. Zheng
Research23 Jan 2013
Nature

Volume: 493, P: 489-494
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

A multi-ancestry genome-wide association study of prostate cancer performed in 156,319 cases and 788,443 controls identifies 187 novel risk variants associated with the disease. Genetic risk scores associated with overall risk, and risk of aggressive disease in men of African ancestry.

Anqi Wang
Jiayi Shen
Christopher A. Haiman
Research09 Nov 2023
Nature Genetics

Volume: 55, P: 2065-2074
Fermi-level-dependent charge-to-spin current conversion by Dirac surface states of topological insulators

The spin–momentum locking of Dirac surface states offers intriguing possibilities for converting between charge and spin currents. Experiments show that fine tuning of the Fermi level is critical for maximizing the efficiency of such conversions.

K. Kondou
R. Yoshimi
Y. Otani
Research25 Jul 2016
Nature Physics

Volume: 12, P: 1027-1031
Thermal hysteresis measurement of the VO₂ emissivity and its application in thermal rectification

C. L. Gomez-Heredia
J. A. Ramirez-Rincon
K. Joulain
ResearchOpen Access31 May 2018
Scientific Reports

Volume: 8, P: 1-11
Impacts of a warming marginal sea on torrential rainfall organized under the Asian summer monsoon

Atsuyoshi Manda
Hisashi Nakamura
Takafumi Miyasaka
ResearchOpen Access18 Jul 2014
Scientific Reports

Volume: 4, P: 1-6
Author Correction: Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Amendments and Corrections14 Mar 2023
Nature Astronomy

Volume: 7, P: 633
Leukemic cells with 11q23 translocations express granulocyte colony-stimulating factor (G-CSF) receptor and their proliferation is stimulated with G-CSF

T Inukai
K Sugita
S Nakazawa
Research30 Apr 1998
Leukemia

Volume: 12, P: 382-389
Effects of induced hypothermia on somatosensory evoked potentials in patients with chronic spinal cord injury

K C Hayes
J T C Hsieh
A R Blight
Research01 Nov 1993
Spinal Cord

Volume: 31, P: 730-741
Loss of heterozygosity on chromosomes 11 and 17 are markers of recurrence in TCC of the bladder

J Edwards
P Duncan
J M S Bartlett
ResearchOpen Access11 Dec 2001
British Journal of Cancer

Volume: 85, P: 1894-1899
Association of immune-related adverse events with durvalumab efficacy after chemoradiotherapy in patients with unresectable Stage III non-small cell lung cancer

Koji Haratani
Atsushi Nakamura
Hidetoshi Hayashi
Research22 Mar 2024
British Journal of Cancer

Volume: 130, P: 1783-1794
Realization of a micrometre-scale spin-wave interferometer

O. Rousseau
B. Rana
Y. Otani
ResearchOpen Access15 May 2015
Scientific Reports

Volume: 5, P: 1-8
Construction of integrated gene logic-chip

DNA origami-based integrated gene transcription modules enable the rational design of transcription activity. Architectural modalities between gene and RNA polymerase allow the autonomous response to various signals with reprogrammable logic gates.

Takeya Masubuchi
Masayuki Endo
Hisashi Tadakuma
Research23 Jul 2018
Nature Nanotechnology

Volume: 13, P: 933-940
Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma

A Ohtsu
H Baba
T Taguchi
ResearchOpen Access20 Jun 2000
British Journal of Cancer

Volume: 83, P: 141-145
HLA-DR antigen expression on colorectal carcinomas: influence of expression by IFN-γ in situ and its association with tumour progression

K Matsushita
T Takenouchi
K Isono
Research01 Mar 1996
British Journal of Cancer

Volume: 73, P: 644-648
Detection of telomerase activity in peritoneal lavage fluid from patients with gastric cancer using immunomagnetic beads

N Mori
M Oka
K Hirose
ResearchOpen Access19 Sept 2000
British Journal of Cancer

Volume: 83, P: 1026-1032
Myelopathy due to lumbar disc herniation in the presence of a tethered cord

F Endo
H Iizuka
K Takagishi
Research06 Jun 2014
Spinal Cord

Volume: 52, P: S11-S13
Three AML patients with existing or pre-existing intracerebral granulocytic sarcomas who were successfully treated with allogeneic bone marrow transplantations

S Takada
K Ito
S Miyawaki
Research23 Mar 1999
Bone Marrow Transplantation

Volume: 23, P: 731-734
Factors affecting the survival of patients with oesophageal carcinoma under radiotherapy in the north of Iran

K O Hajian-Tilaki
ResearchOpen Access27 Nov 2001
British Journal of Cancer

Volume: 85, P: 1671-1674
Effects of interleukin-2 and interferon-αA/D treatment on lymphocytes from tumour-bearing mice

M Iigo
Y Nakajima
A Hoshi
Research01 Jun 1989
British Journal of Cancer

Volume: 59, P: 883-888
Phase II trial of docetaxel in advanced or metastatic endometrial cancer: a Japanese Cooperative Study

N Katsumata
K Noda
F Eguchi
ResearchOpen Access18 Oct 2005
British Journal of Cancer

Volume: 93, P: 999-1004
Drug sensitivity testing for clinical samples from oesophageal cancer using adhesive tumour cell culture system

M Terashima
K Hayashi
T Yanagawa
Research01 Jul 1996
British Journal of Cancer

Volume: 74, P: 73-77
Phase II study of S-1, a novel oral fluorouracil, in advanced non-small-cell lung cancer

M Kawahara
K Furuse
H Niitani
ResearchOpen Access02 Oct 2001
British Journal of Cancer

Volume: 85, P: 939-943
Detection of ultrafast electron energization by whistler-mode chorus waves in the magnetosphere of Earth

S. Kurita
Y. Miyoshi
I. Shinohara
ResearchOpen Access14 Jan 2025
Scientific Reports

Volume: 15, P: 1-11

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