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Engineering oriented shape optimization of GHT-Bézier developable surfaces using a meta heuristic approach with CAD/CAM applications

Samia BiBi
Md Yushalify Misro
Emad E. Mahmoud
ResearchOpen Access05 Aug 2025
Scientific Reports

Volume: 15, P: 1-36
NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing

NSD1, which deposits H3K36me2, is a major regulator of DNA methylation in male but not in female gametogenesis. NSD1 safeguards against H3K27me3-associated transcriptional silencing.

Kenjiro Shirane
Fumihito Miura
Matthew C. Lorincz
Research14 Sept 2020
Nature Genetics

Volume: 52, P: 1088-1098
Oral Pretreatment with Ebselen Enhances Heat Shock Protein 72 Expression and Reduces Myocardial Infarct Size

Erdenechimeg Baljinnyam
Naoyuki Hasebe
Kenjiro Kikuchi
Research01 Nov 2006
Hypertension Research

Volume: 29, P: 905-913
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

De novo DNA methylation during mouse oogenesis occurs within transcribed regions. Here the authors investigate the role of species-specific long terminal repeats (LTRs)-initiated transcription units in regulating the oocyte methylome, identifying syntenic regions in mouse, rat and human with divergent DNA methylation associated with private LITs.

Julie Brind’Amour
Hisato Kobayashi
Matthew C. Lorincz
ResearchOpen Access20 Aug 2018
Nature Communications

Volume: 9, P: 1-14
Calciprotein particle-induced cytotoxicity via lysosomal dysfunction and altered cholesterol distribution in renal epithelial HK-2 cells

Rina Kunishige
Mai Mizoguchi
Masayuki Murata
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-18
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14

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Engineering oriented shape optimization of GHT-Bézier developable surfaces using a meta heuristic approach with CAD/CAM applications

NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing

Oral Pretreatment with Ebselen Enhances Heat Shock Protein 72 Expression and Reduces Myocardial Infarct Size

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

Calciprotein particle-induced cytotoxicity via lysosomal dysfunction and altered cholesterol distribution in renal epithelial HK-2 cells

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

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