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Showing 1–2 of 2 results
Advanced filters: Author: Keya Joshi Clear advanced filters

  • The M5 muscarinic acetylcholine receptor represents a promising therapeutic target for neurological disorders. Here, the authors reveal a 2.1 Å cryo-EM structure of the M5 bound to a selective positive allosteric modulator site that enables structure-based drug design.

    • Wessel A. C. Burger
    • Jesse I. Mobbs
    • David M. Thal
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15