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Advanced filters: Author: Khaldoun Almhanna Clear advanced filters

  • Dickkopf-related protein 1 (DKK1) is a secreted protein associated with poorer outcomes in patients with gastric cancer. Here, the authors report part B of the DisTinGuish phase II trial reporting the safety and efficacy of DKN-01 (DKK1 neutralising antibody) in combination with tislelizumab (anti-PD-1) in patients with advanced gastric/gastoesophageal junction cancer and elevated DKK1 expression.

    • Keun-Wook Lee
    • Devalingam Mahalingam
    • Samuel J. Klempner
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-8