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Showing 1–8 of 8 results
Advanced filters: Author: Kohki Takahashi Clear advanced filters

  • The protein kinase ASK1 has been linked to cellular stress responses. Here the authors show that ASK1 also regulates gene expression and activity of beige and brown adipocytes, and demonstrate adipocyte ASK1 has a physiological role in regulating thermogenesis in mice.

    • Kazuki Hattori
    • Isao Naguro
    • Hidenori Ichijo
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-10

  • HeLa cell culture was enhanced on the film prepared from poly(l-lactide)-poly(ɛ-caprolactone) (PLLA-PCL) and poly(L-lactide-co-glycolide)-poly(ɛ-caprolactone) (PLGA-PCL) multiblock copolymers (MBCs) without any coatings or treatments. (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT) reduction assay quantitatively showed the enhanced proliferation of HeLa cells on the MBC films in comparison with the film prepared from a PLLA-PCL random copolymer. The microphase-separated morphology of the multiblock copolymers plays an important role in protein adhesion behavior and subsequent cell proliferation.

    • Takahiro Suga
    • Nguyen T Xuyen
    • Taku Tamura
    Research
    Polymer Journal
    Volume: 49, P: 567-573

  • Magnetic-field-induced alignment of low-molecular-weight syndiotactic polystyrene (sPS) has achieved. Isothermal crystallization from the melting state containing local ordered domains under the 2 or 10 T of the magnetic-field-induced alignment of sPS crystals. The crystalized sPS samples formed the β phase, and the b-axis was aligned parallel to the magnetic field. Low molecular weight of sPS and high magnetic field were effective for high alignment degree. A stepwise crystallization attained higher alignment of sPS compared with an isothermal crystallization.

    • Naofumi Naga
    • Yoshie Saito
    • Masafumi Yamato
    Research
    Polymer Journal
    Volume: 48, P: 709-714