Nature Search

Initial sequencing and comparative analysis of the mouse genome

Asif T. Chinwalla
Lisa L. Cook
Michael C. Zody
Research05 Dec 2002
Nature

Volume: 420, P: 520-562
Modeling human adaptive immune responses with tonsil organoids

An in vitro human tonsil tissue-based system captures key features of a functional germinal center and can be used to study humoral immune responses to vaccines, new antigens and adjuvants.

Lisa E. Wagar
Ameen Salahudeen
Mark M. Davis
Research11 Jan 2021
Nature Medicine

Volume: 27, P: 125-135
Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice

TGF-β signaling is required for microglial homeostasis, however the source of ligands in the adult brain is unknown. Here, the authors show that microglial homeostasis relies on microglia-derived TGF-β1 ligand via an autocrine mechanism, which is also important for astrocyte homeostasis.

Alicia Bedolla
Elliot Wegman
Yu Luo
ResearchOpen Access21 Jun 2024
Nature Communications

Volume: 15, P: 1-25
Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Richard A. Gibbs
George M. Weinstock
Francis Collins
Research01 Apr 2004
Nature

Volume: 428, P: 493-521
Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth

A subset of HIV-infected individuals can develop broadly neutralizing antibodies. Boyd and colleagues studied such HIV-infected individuals and found significant perturbations in their antibody repertoires, including increased frequencies of B cells expressing antibodies with features associated with autoreactivity.

Krishna M. Roskin
Katherine J. L. Jackson
Scott D. Boyd
Research20 Jan 2020
Nature Immunology

Volume: 21, P: 199-209
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Longitudinal sampling is used to map the evolution of an HIV-1 virus from the time of infection, and the co-evolution of a broadly neutralizing antibody in the same infected patient; the findings have important implications for HIV vaccine development.

Hua-Xin Liao
Rebecca Lynch
Barton F. Haynes
Research03 Apr 2013
Nature

Volume: 496, P: 469-476
Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

Immunologic memory promotes faster and more-efficient responses after re-exposure to pathogens. Ahmed and colleagues characterize a subset of human B cells that arise after vaccination against or exposure to influenza or Ebola virus and contribute to the memory cell pool.

Ali H Ellebedy
Katherine J L Jackson
Rafi Ahmed
Research15 Aug 2016
Nature Immunology

Volume: 17, P: 1226-1234
Chromatin structure predicts survival in glioma patients

Matthew C. Garrett
Rebecca Albano
Richard Lu
ResearchOpen Access17 May 2022
Scientific Reports

Volume: 12, P: 1-9
HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma

Matthew C. Garrett
Rebecca Albano
Q. Richard Lu
ResearchOpen Access01 Aug 2023
Scientific Reports

Volume: 13, P: 1-12

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