Nature Search

Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Genome-wide association meta-analyses of attention-deficit/hyperactivity disorder symptom measures and clinical diagnoses identify new risk loci, highlight putative effector genes and yield improved polygenic risk scores.

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Research17 Sept 2025
Nature Genetics

P: 1-9
A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison

The authors report a meta-analysis of methylome-wide association studies, identifying 15 significant CpG sites linked to major depression, revealing associations with inflammatory markers and suggesting potential causal relationships through Mendelian randomization analysis.

Xueyi Shen
Miruna Barbu
Andrew M. McIntosh
ResearchOpen Access16 Sept 2025
Nature Mental Health

Volume: 3, P: 1152-1167
Publisher Correction: Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genes

Camiel M. van der Laan
Hill F. Ip
Dorret I. Boomsma
Amendments and Corrections29 Sept 2025
Nature Genetics

P: 1
Insights from a methylome-wide association study of antidepressant exposure

The mechanism of currently prescribed antidepressants is incompletely understood. Here, the study identifies associations between antidepressant use and DNA methylation, highlighting shared signals across datasets, and tissue enrichment in the amygdala.

E. Davyson
X. Shen
A. M. McIntosh
ResearchOpen Access24 Feb 2025
Nature Communications

Volume: 16, P: 1-15
Genetic associations with parental investment from conception to wealth inheritance in six cohorts

A study in 36,516 parents across six international cohorts reveals that parental genetic effects are associated with the investments that parents make in their offspring, from adopting more healthy behaviours during pregnancy to leaving wealth to adult children.

Jasmin Wertz
Terrie E. Moffitt
Avshalom Caspi
ResearchOpen Access29 Jun 2023
Nature Human Behaviour

Volume: 7, P: 1388-1401
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

DNA methylation quantitative trait locus (mQTL) analyses on 32,851 participants identify genetic variants associated with DNA methylation at 420,509 sites in blood, resulting in a database of >270,000 independent mQTLs.

Josine L. Min
Gibran Hemani
Caroline L. Relton
Research06 Sept 2021
Nature Genetics

Volume: 53, P: 1311-1321
Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction

Genomic structural equation modeling of genome-wide association data for educational attainment and cognitive test performance is used to estimate the genetic component of variation in educational attainment that is independent of cognitive ability. The study finds that noncognitive skills account for 57% of genetic variation in educational attainment.

Perline A. Demange
Margherita Malanchini
Michel G. Nivard
Research07 Jan 2021
Nature Genetics

Volume: 53, P: 35-44
Chronic Adolescent Exposure to Delta-9-Tetrahydrocannabinol in COMT Mutant Mice: Impact on Indices of Dopaminergic, Endocannabinoid and GABAergic Pathways

Áine T Behan
Magdalena Hryniewiecka
David R Cotter
Research21 Mar 2012
Neuropsychopharmacology

Volume: 37, P: 1773-1783
Chronic Adolescent Exposure to Δ-9-Tetrahydrocannabinol in COMT Mutant Mice: Impact on Psychosis-Related and Other Phenotypes

Colm MP O'Tuathaigh
Magdalena Hryniewiecka
John L Waddington
Research14 Jul 2010
Neuropsychopharmacology

Volume: 35, P: 2262-2273
Genetics and the geography of health, behaviour and attainment

Data from a cohort of US and UK adolescents reveal that genetic and neighbourhood risks for early pregnancy and educational attainment are correlated, but find a weak or no correlation between risks for obesity or schizophrenia.

Daniel W. Belsky
Avshalom Caspi
Candice L. Odgers
Research08 Apr 2019
Nature Human Behaviour

Volume: 3, P: 576-586
Leptin deficiency in maltreated children

A Danese
R Dove
L Arseneault
ResearchOpen Access23 Sept 2014
Translational Psychiatry

Volume: 4, P: e446
Expert elicitation of state shifts and divergent sensitivities to climate warming across northern ecosystems

Warming-induced changes in permafrost, peatlands, lakes, snowpack, vegetation, and vertebrates could impact northern ecosystem integrity, with different response times across components and latitude, according to an expert assessment of sensitivity in northern landscapes.

Émilie Saulnier-Talbot
Éliane Duchesne
Joël Bêty
ResearchOpen Access25 Oct 2024
Communications Earth & Environment

Volume: 5, P: 1-15
Clinical genome sequencing in patients with suspected rare genetic disease in Peru

Jeny Bazalar-Montoya
Mario Cornejo-Olivas
Ryan J. Taft
ResearchOpen Access28 Oct 2024
npj Genomic Medicine

Volume: 9, P: 1-10
Establishing a generalized polyepigenetic biomarker for tobacco smoking

Karen Sugden
Eilis J. Hannon
Avshalom Caspi
ResearchOpen Access15 Feb 2019
Translational Psychiatry

Volume: 9, P: 1-12
Decadal Variations in Eastern Canada’s Taiga Wood Biomass Production Forced by Ocean-Atmosphere Interactions

Etienne Boucher
Antoine Nicault
Mehdi Pasha Karami
ResearchOpen Access26 May 2017
Scientific Reports

Volume: 7, P: 1-13
Genetic association study of childhood aggression across raters, instruments, and age

Hill F. Ip
Camiel M. van der Laan
Dorret I. Boomsma
ResearchOpen Access30 Jul 2021
Translational Psychiatry

Volume: 11, P: 1-9
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

M Maftouh
A Avan
E Giovannetti
ResearchOpen Access31 Oct 2013
British Journal of Cancer

Volume: 110, P: 172-182
Adolescent Cannabis Exposure Alters Opiate Intake and Opioid Limbic Neuronal Populations in Adult Rats

Maria Ellgren
Sabrina M Spano
Yasmin L Hurd
Research05 Jul 2006
Neuropsychopharmacology

Volume: 32, P: 607-615
DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

Jenny van Dongen
Fiona A. Hagenbeek
Dorret I. Boomsma
ResearchOpen Access08 Jan 2021
Molecular Psychiatry

Volume: 26, P: 2148-2162
Latency and interval therapy affect the evolution in metastatic colorectal cancer

Hamid Nikbakht
Selin Jessa
Donna M. Graham
ResearchOpen Access17 Jan 2020
Scientific Reports

Volume: 10, P: 1-10
Longitudinal investigation of DNA methylation changes preceding adolescent psychotic experiences

Susanna Roberts
Matthew Suderman
Helen L. Fisher
ResearchOpen Access04 Feb 2019
Translational Psychiatry

Volume: 9, P: 1-12
Author Correction: Expert elicitation of state shifts and divergent sensitivities to climate warming across northern ecosystems

Émilie Saulnier-Talbot
Éliane Duchesne
Joël Bêty
Amendments and CorrectionsOpen Access26 Dec 2024
Communications Earth & Environment

Volume: 5, P: 1
Biological embedding of stress through inflammation processes in childhood

A Danese
A Caspi
L Arseneault
Correspondence16 Feb 2010
Molecular Psychiatry

Volume: 16, P: 244-246
Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study

I Shalev
T E Moffitt
A Caspi
Research24 Apr 2012
Molecular Psychiatry

Volume: 18, P: 576-581

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