Voxel-based morphometry (VBM) involves comparisons of high resolution structural images of the brain between groups, but what causes changes in the VBM signal is unclear. Here the authors perform a VBM study of Thy1-YFP mice following auditory fear conditioning and propose that the signal changes can be partially explained by increases in dendritic spine density.
- O. P. Keifer Jr
- R. C. Hurt
- K. J. Ressler