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Linking emotional valence and anxiety in a mouse insula-amygdala circuit

The existence of a common substrate for emotional valence and anxiety remained elusive. Here we show that excitatory neurons of the anterior insular cortex (aIC), including neurons projecting to the basolateral amygdala (aIC-BLA) encode both states.

C. Nicolas
A. Ju
A. Beyeler
ResearchOpen Access21 Aug 2023
Nature Communications

Volume: 14, P: 1-18
Salvage prostate intensity modulated radiation therapy after cryotherapy failure

Tanguy Perennec
Maximilien Rogé
Stéphane Supiot
ResearchOpen Access21 Apr 2024
Scientific Reports

Volume: 14, P: 1-6
Hypoxia, DNA repair and genetic instability

Intratumoural hypoxia is a negative prognostic indicator and can underlie therapeutic resistance for many patients. This Review explores the differential biological effects of acute hypoxia versus longer-term, chronic hypoxia on genomic instability and DNA damage repair pathways. What does this mean for therapeutic strategies?

Robert G. Bristow
Richard P. Hill
Reviews01 Mar 2008
Nature Reviews Cancer

Volume: 8, P: 180-192
Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer

Maureen Labbé
Manon Chang
Delphine Fradin
ResearchOpen Access16 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-12
Synergistic action of image-guided radiotherapy and androgen deprivation therapy

The authors discuss the combined use of androgen deprivation therapy and image-guided radiotherapy (IGRT) in aggressive, localized prostate cancer. They also describe how it is imperative to identify the patients who would benefit from this combined-modality therapy relative to the use of IGRT alone and the opportunities for more personalized approaches in treating this disease.

Jennifer A. Locke
Alan Dal Pra
Robert G. Bristow
Reviews24 Mar 2015
Nature Reviews Urology

Volume: 12, P: 193-204
Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes

Perrine Paul-Gilloteaux
Vincent Potiron
Sylvain V. Costes
ResearchOpen Access23 May 2017
Scientific Reports

Volume: 7, P: 1-14
The current landscape of stereotactic body radiation therapy for metastatic castration-resistant prostate cancer

Jennifer Le Guevelou
Francesco Cuccia
David Pasquier
Reviews19 Jun 2024
Prostate Cancer and Prostatic Diseases

Volume: 28, P: 546-556

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Linking emotional valence and anxiety in a mouse insula-amygdala circuit

Salvage prostate intensity modulated radiation therapy after cryotherapy failure

Hypoxia, DNA repair and genetic instability

Loss of miR-200c-3p promotes resistance to radiation therapy via the DNA repair pathway in prostate cancer

Synergistic action of image-guided radiotherapy and androgen deprivation therapy

Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes

The current landscape of stereotactic body radiation therapy for metastatic castration-resistant prostate cancer

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