The authors studied AMPAR-mediated currents in cerebellar stellate cells from stargazer mice, which lack the prototypical TARP stargazin (γ-2). They report that calcium-permeable AMPARS can localize at synapses in the absence of stargazin; moreover, mEPSCs mediated by TARPless AMPARs were also detected in these cells following knockdown of their only other TARP, γ-7.
- Cécile Bats
- David Soto
- Stuart G Cull-Candy