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Showing 1–50 of 120 results

Advanced filters: Author: L. de Waal Clear advanced filters

Structural basis of lipopolysaccharide maturation by the O-antigen ligase

Cryo-electron microscopy structures of the bacterial O-antigen ligase WaaL, combined with genetics, biochemistry and molecular dynamics simulations, provide insight into the mechanism by which WaaL catalyses the biosynthesis of lipopolysaccharide.

Khuram U. Ashraf
Rie Nygaard
Filippo Mancia
Research06 Apr 2022
Nature

Volume: 604, P: 371-376
Fair refusal by capuchin monkeys

Clive D. L. Wynne
Research11 Mar 2004
Nature

Volume: 428, P: 140
The perils of anthropomorphism

Consciousness should be ascribed to animals only with extreme caution.

Clive D. L. Wynne
Comments & Opinion08 Apr 2004
Nature

Volume: 428, P: 606
Dutch population structure across space, time and GWAS design

Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.

Ross P. Byrne
Wouter van Rheenen
Russell L. McLaughlin
ResearchOpen Access11 Sept 2020
Nature Communications

Volume: 11, P: 1-11
South African Senecio Alkaloids

H. L. DE WAAL
Research14 Dec 1940
Nature

Volume: 146, P: 777-778
Healthy competition

Noxious cyanobacteria pose a considerable health threat to freshwater ecosystems. Research now suggests that toxic strains may be outcompeted by their non-toxic counterparts as surface concentrations of carbon dioxide increase.

Steven W. Wilhelm
Gregory L. Boyer
News & Views26 Aug 2011
Nature Climate Change

Volume: 1, P: 300-301
Raman Effect of the Isomers of Benzene Hexachloride

S. M. NAUDÉ
H. VERLEGER
H. L. DE WAAl
Research16 Sept 1950
Nature

Volume: 166, P: 475
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei

Shigella sonnei is divided into five lineages and most infections are caused by Lineage 3. Here, the authors investigate factors contributing to the epidemiological success of Lineage 3 through comparative genomics and virulence analyses in a zebrafish infection model.

Sydney L. Miles
Dilys Santillo
Serge Mostowy
ResearchOpen Access09 Oct 2025
Nature Communications

Volume: 16, P: 1-14
Structure, biosynthesis and regulation of the T1 antigen, a phase-variable surface polysaccharide conserved in many Salmonella serovars

Some Salmonella isolates produce an enigmatic, transient antigen known as T1. Here, Kelly et al. show that T1 is a complex linear glycan linked to lipid A–core, like a typical O antigen, and is expressed in a phase-variable manner regulated by recombinational inversion of a promoter upstream of the T1 genetic locus.

Steven D. Kelly
Mikel Jason Allas
Chris Whitfield
ResearchOpen Access02 Aug 2024
Nature Communications

Volume: 15, P: 1-13
Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity

R. Bernards
P. I. Schrier
C. J. M. Melief
Research27 Oct 1983
Nature

Volume: 305, P: 776-779
Atomic structure of a human MHC molecule presenting an influenza virus peptide

Michael L. Silver
Hwai-Chen Guo
Don C. Wiley
Research26 Nov 1992
Nature

Volume: 360, P: 367-369
Payment for labour in monkeys

Capuchins will voluntarily share treats with other monkeys that helped to secure them.

Frans B. M. de Waal
Michelle L. Berger
Research06 Apr 2000
Nature

Volume: 404, P: 563
Infectious parvovirus B19 circulates in the blood coated with active host protease inhibitors

This study presents the first high-resolution structure of infectious parvovirus B19, purified from a patient. Two acute phase reactants, serpinA3, and ITIH4, bind to the capsid, suggesting B19V utilizes host proteins during viremia for survival and function.

Hyunwook Lee
Ruben Assaraf
Carlos Ros
ResearchOpen Access05 Nov 2024
Nature Communications

Volume: 15, P: 1-15
Bacterial polysaccharide co-polymerases share a common framework for control of polymer length

Ante Tocilj
Christine Munger
Miroslaw Cygler
Research20 Jan 2008
Nature Structural & Molecular Biology

Volume: 15, P: 130-138
Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering

Lipid nanoparticles (LNPs) are the preeminent drug delivery vehicle for mRNA therapies, partially due to the ionizable lipid (IL) components that facilitate endosomal escape. Here, authors devise terminally branched ILs that enhance endosome escape, resulting in increased liver and T cell delivery.

Marshall S. Padilla
Kaitlin Mrksich
Michael J. Mitchell
ResearchOpen Access24 Jan 2025
Nature Communications

Volume: 16, P: 1-19
Cytogenetic mapping of the duplicated segment of chromosome 12 in lymphoproliferative disorders

G. Gahrton
K.-H. Robert
L. Zech
Research10 Jun 1982
Nature

Volume: 297, P: 513-514
Variable expression of Ia antigens on the vascular endothelium of mouse skin allografts

R. M. W. de Waal
M. J. J. Bogman
R. A. P. Koene
Research02 Jun 1983
Nature

Volume: 303, P: 426-429
Early responses to chemotherapy detected by pulse cytophotometry

L A Smets
E Mulder
J Blok
Research01 Aug 1976
British Journal of Cancer

Volume: 34, P: 153-161
Systematic analyses identify modes of action of ten clinically relevant biocides and antibiotic antagonism in Acinetobacter baumannii

Genomic fitness profiling of Acinetobacter baumannii treated with ten clinically relevant biocides using TraDIS reveals a common mechanism of action through dissipation of membrane potential that can promote antibiotic tolerance.

Liping Li
Francesca L. Short
Ian T. Paulsen
Research09 Oct 2023
Nature Microbiology

Volume: 8, P: 1995-2005
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

W. K. Cavenee
T. P. Dryja
R. L. White
Research27 Oct 1983
Nature

Volume: 305, P: 779-784
Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

Douglas E. Brenneman
Gary L. Westbrook
Candace B. Pert
Research13 Oct 1988
Nature

Volume: 335, P: 639-642
A human monoclonal antibody binds within the poliovirus receptor-binding site to neutralize all three serotypes

Cross-neutralizing activity of monoclonal antibodies against poliovirus serotypes is less commonly reported. In this study, the authors use high-resolution cryo-EM to reveal that a cross-neutralizing human antibody neutralizes all three poliovirus serotypes by interacting with the receptor-binding region, called the canyon.

Andrew J. Charnesky
Julia E. Faust
Susan L. Hafenstein
ResearchOpen Access10 Oct 2023
Nature Communications

Volume: 14, P: 1-11
Canopy functional trait variation across Earth’s tropical forests

Data from a variety of sources—including satellite, climate and soil data, as well as field-collected information on plant traits—are pooled and analysed to map the functional diversity of tropical forest canopies globally.

Jesús Aguirre-Gutiérrez
Sami W. Rifai
Yadvinder Malhi
ResearchOpen Access05 Mar 2025
Nature

Volume: 641, P: 129-136
Extreme weather event attribution predicts climate policy support across the world

Literature produced inconsistent findings regarding the links between extreme weather events and climate policy support across regions, populations and events. This global study offers a holistic assessment of these relationships and highlights the role of subjective attribution.

Viktoria Cologna
Simona Meiler
Amber Zenklusen
ResearchOpen Access01 Jul 2025
Nature Climate Change

Volume: 15, P: 725-735
Recognition of cluster of differentiation 1 antigens by human CD4⁻CD8^>− cytolytic T lymphocyte

Steven Porcelli
Michael B. Brenner
Paul A. Bleicher
Research05 Oct 1989
Nature

Volume: 341, P: 447-450
The biosynthetic origin of ribofuranose in bacterial polysaccharides

Ribofuranose residues are installed on O-antigens of bacterial polysaccharides by a dual-activity enzyme that uses phosphoribosyl-5-phospho-d-ribosyl-α-1-diphosphate as a sugar donor and also catalyzes phosphate hydrolysis.

Steven D. Kelly
Danielle M. Williams
Chris Whitfield
Research07 Apr 2022
Nature Chemical Biology

Volume: 18, P: 530-537
Grooming, alliances and reciprocal altruism in vervet monkeys

Robert M. Seyfarth
Dorothy L. Cheney
Research05 Apr 1984
Nature

Volume: 308, P: 541-543
Trust in scientists and their role in society across 68 countries

What is the state of trust in scientists around the world? To answer this question, the authors surveyed 71,922 respondents in 68 countries and found that trust in scientists is moderately high.

Viktoria Cologna
Niels G. Mede
Rolf A. Zwaan
ResearchOpen Access20 Jan 2025
Nature Human Behaviour

Volume: 9, P: 713-730
High interleukin-10 serum levels are associated with fatal outcome in patients after bone marrow transplantation

L Hempel
D Körholz
F Zintl
Research01 Sept 1997
Bone Marrow Transplantation

Volume: 20, P: 365-368
Peptide selection by MHC class I molecules

Ton N. M. Schumacher
Marloes L. H. De Bruijn
Hidde L. Ploegh
Research25 Apr 1991
Nature

Volume: 350, P: 703-706
Observational social learning of “know-how” and “know-what” in wild orangutans: evidence from nest-building skill acquisition

Observational social learning shapes nest-building skill acquisition in wild orangutans showing selective attention to 'know-how' and transmission of 'know-what' across developmental stages.

Andrea L. Permana
Junaidi Jaka Permana
Caroline Schuppli
ResearchOpen Access07 Jun 2025
Communications Biology

Volume: 8, P: 1-11
Thymic epithelium and the induction of transplantation tolerance in nude mice

R. K. Jordan
J. H. Robinson
A. L. Bentley
Research01 Apr 1985
Nature

Volume: 314, P: 454-456
Room temperature energy-efficient spin-orbit torque switching in two-dimensional van der Waals Fe₃GeTe₂ induced by topological insulators

Magnetic random access memory (MRAM) exhibits remarkable device endurance, while also offering potential operation speed and energy efficiency improvements compared to conventional random access memory. However, challenges remain, both in terms of efficiency, and miniaturization. Here, Wang et al demonstrate a van der Waals (vdW) based spin-orbit torque switching, in a Fe₃GeTe₂/Bi2Te₃ heterostructure, paving the way for thinner and higher efficiency spin-orbit torque based vdW MRAM.

Haiyu Wang
Hao Wu
Weisheng Zhao
ResearchOpen Access24 Aug 2023
Nature Communications

Volume: 14, P: 1-9
HLA-restricted recognition of viral antigens in HLA transgenic mice

Femia Kievits
Pavol Ivanyi
Hidde L. Ploegh
Research01 Oct 1987
Nature

Volume: 329, P: 447-449
Decreased interleukin 10 and increased interferon-γ production in patients with chronic graft-versus-host disease after allogeneic bone marrow transplantation

D Körholz
D Kunst
S Burdach
Research01 Apr 1997
Bone Marrow Transplantation

Volume: 19, P: 691-695
37 Early Nasal Continuous Positive Airway Pressure (Ncpap) in Combination with Early Curative Surfactant Therapy in Preterm Infants Less Than 28 Weeks Ga

F Boubred
L Fayol
U Simeoni
Research01 Sept 2004
Pediatric Research

Volume: 56, P: 470
The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

Bacteria produce small iron-binding molecules called siderophores, which are recognised by outer-membrane transporters. Here, the authors show that a Pseudomonas transporter recognises the siderophore enterobactin using extracellular loops distant from the pore, and propose that there is a second binding site deeper inside the structure.

Lucile Moynié
Stefan Milenkovic
James H. Naismith
ResearchOpen Access14 Aug 2019
Nature Communications

Volume: 10, P: 1-14
Children Born Small for Gestational Age: Do They Catch Up?

A C S Hokken-Koelega
M A J De Ridder
S L S Drop
Research01 Aug 1995
Pediatric Research

Volume: 38, P: 267-271
Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion

J H W de Wilt
T L M ten Hagen
A M M Eggermont
ResearchOpen Access03 Feb 2000
British Journal of Cancer

Volume: 82, P: 1000-1003
Dilepton production in hadronic collisions

L. M. Lederman
Reviews26 Apr 1979
Nature

Volume: 278, P: 827-832
Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats

J H W de Wilt
E R Manusama
A M M Eggermont
ResearchOpen Access26 Mar 1999
British Journal of Cancer

Volume: 80, P: 161-166
High-resolution magnetic resonance imaging of the normal extraocular musculature

A Ettl
J Kramer
L Koornneef
Research01 Nov 1997
Eye

Volume: 11, P: 793-797
Sub-micron level investigation reveals the inaccessibility of stabilized carbon in soil microaggregates

Pavithra S. Pitumpe Arachchige
Ganga M. Hettiarachchi
Jackson E. Fiorin
ResearchOpen Access14 Nov 2018
Scientific Reports

Volume: 8, P: 1-13
Synergistic effects of TNF-α and melphalan in an isolated limb perfusion model of rat sarcoma: a histopathological, immunohistochemical and electron microscopical study

PTGA Nooijen
ER Manusama
DJ Ruiter
Research01 Dec 1996
British Journal of Cancer

Volume: 74, P: 1908-1915
THE IMMUNE RESPONSE TO GRF (1–44) NH₂ AND GRF (1–29) NH₂AS A PROBE OF CONFORMATION IN VIVO

H J Zeisel
K-G Petersen
L Kerp
Research01 Jan 1988
Pediatric Research

Volume: 23, P: 110
Porcelain shards from Portuguese wrecks: Raman spectroscopic analysis of marine archaeological ceramics

Elizabeth A. Carter
Michelle L. Wood
Howell G. M. Edwards
ResearchOpen Access04 May 2017
Heritage Science

Volume: 5, P: 1-8
Effects of early-life antibiotics on the developing infant gut microbiome and resistome: a randomized trial

Here, in a randomized trial of 147 infants receiving distinct antibiotic regimens for early-onset neonatal sepsis, Reyman et al. characterize the gut microbiome and resistance profiles, finding differential effects of antibiotic combinations on microbial community composition and antimicrobial resistance genes.

Marta Reyman
Marlies A. van Houten
Debby Bogaert
ResearchOpen Access16 Feb 2022
Nature Communications

Volume: 13, P: 1-12
Nitric oxide synthase inhibition results in synergistic anti-tumour activity with melphalan and tumour necrosis factor alpha-based isolated limb perfusions

J H W de Wilt
E R Manusama
T L M ten Hagen
ResearchOpen Access10 Oct 2000
British Journal of Cancer

Volume: 83, P: 1176-1182
IMPROVED EFFICIENCY OF A TSH SCREENING PROGRAM BY INTRODUCTION OF A TIME RESOLVED FLUORO IMMUNOASSAY (DELFIAR)

A Grueters
D L'Allemand
H Helge
Research01 Nov 1986
Pediatric Research

Volume: 20, P: 1193
Venatorbacter cucullus gen. nov sp. nov a novel bacterial predator

Ahmed Saeedi
Nicola J. Cummings
Phillippa L. Connerton
ResearchOpen Access01 Nov 2021
Scientific Reports

Volume: 11, P: 1-13

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