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The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

Thirty years of forest demographic data, combined with recent ecophysiological measurements, reveal that intense Amazon droughts sharply increase tree mortality once soil moisture falls below a threshold, and that these hot droughts will become more frequent and intense as Earth warms towards hypertropical conditions.

Like their optical counterparts, acoustic metamaterials are capable of manipulating sound waves in unusual ways. An acoustic hyperlens is now demonstrated that is capable of magnifying subwavelength acoustic waves, and could therefore find applications in medical imaging or underwater sonar.

A century ago this week, physicist Lawrence Bragg announced an equation that revolutionized fields from mineralogy to biology, writes John Meurig Thomas.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A benchtop fusion reactor, called the Thunderbird Reactor, is described, showing that electrochemically loading a metal lattice with deuterium could enhance nuclear fusion rates when that metal is also bombarded by deuterium ions.

Superlattices, with a length scale and structure that differs from the parent lattice of the host material, are well-known to allow for remarkable new electronic and magnetic properties. Here, Xie et al. synthesize Cr_1/4TaS₂, and find that it exhibits an unusual anomalous Hall effect below the Néel temperature even in stoichiometric high-quality crystals.

The most up-to-date combination of results on the properties of the Higgs boson is reported, which indicate that its properties are consistent with the standard model predictions, within the precision achieved to date.

Reninomas are very rare kidney tumours of juxtaglomerular cells. Here, the authors analyse reninomas using whole-genome and transcriptome sequencing, and reveal the presence and functional effects of NOTCH1 rearrangements.

Whole-genome sequencing data from more than 2,500 cancers of 38 tumour types reveal 16 signatures that can be used to classify somatic structural variants, highlighting the diversity of genomic rearrangements in cancer.

A pan-cancer genomic analysis reports the effects of structural variations on chromatin domains (TADs). Most TAD disruptions do not result in appreciable changes in expression of nearby genes.

Trivalent lanthanides are typically described using an ionic picture that leads to localized magnetic moments. Here authors show that the “textbook” description of lanthanides fails for Pr⁴⁺ ions where the hierarchy of single-ion energy scales can be tailored to explore correlated phenomena in quantum materials.

The CMS Collaboration reports evidence for off-shell Higgs boson contributions in the production of Z boson pairs, and measures the width of the Higgs boson, which is inversely related to its lifetime.

The CMS Collaboration reports the study of three simultaneous hard interactions between quarks and gluons in proton–proton collisions. This manifests through the concurrent production of three J/ψ mesons, which consist of a charm-quark–antiquark pair.

A solid-state single-electron qubit platform is demonstrated based on trapping and manipulating isolated single electrons on an ultraclean solid neon surface in vacuum, which performs near the state of the art for a charge qubit.

Charge programmed additive manufacturing seamlessly integrates multiple material classes and provides a universal platform for rapid printing of ultralight antennas. It propels discovery of antenna designs with unprecedented structural complexity.

Efficient, large-scale genomic analysis is facilitated on the cloud by a computational tool with error-diagnosing and self-healing capabilities.

Current muon beams have a phase-space volume that is too large for applications in muon colliders. Now, the reduction in the beam’s transverse emittance when passed through different absorbers in ionization cooling experiments is quantified.

The FANCM helicase functions in limiting crossovers (COs) by unwinding inter-homolog repair intermediates. Here, the authors generate null mutants of fancm in tetraploid and hexaploid wheat and show that FANCM promotes class I interfering COs and suppresses class II noninterfering COs in wheat meiosis.

Understanding the location and nature of the catalytic active site is critical for controlling a catalyst’s activity and selectivity. Here, the authors separate the metal from the support by a controlled distance while maintaining the ability to promote defects via the use of carbon nanotube hydrogen highways.

A portable prototype scanner for brain MRI that uses a compact and lightweight permanent rare-earth magnet with a built-in readout field gradient generates clinically relevant images of the brain, as shown in adult volunteers.

Here, Hiatt et al. report the knock-out of over 400 genes in primary CD4+ T cells to assess their functional role in HIV replication, finding 86 initial candidates of which 47 are validated as HIV host factors, including 23 with restrictive activity.

Electrode–domain wall junctions in ferroelectric ErMnO₃ act as nanoscale diodes.

Platelets accumulate on the downstream face of a developing blood clot after local changes in blood flow. These findings offer new insights into how platelets pile up at sites of vascular injury (pages 665–673).

A short segment of α-synuclein called NACore (residues 68–78) is responsible for the formation of amyloid aggregates responsible for cytotoxicity in Parkinson disease; here the nanocrystal structure of this invisible-to-optical-microscopy segment is determined using micro-electron diffraction, offering insight into its function and simultaneously demonstrating the first use of micro-electron diffraction to solve a previously unknown protein structure.

Ionization cooling, a technique that delivers high-brightness muon beams for the study of phenomena at energy scales beyond those of the Large Hadron Collider, is demonstrated by the Muon Ionization Cooling Experiment.

The dispersion of metal–organic framework nanocrystals within a polyimide yields membranes for selective chemical separations with strong resistance to plasticization.

Wijerathne et al develop an approach to quantify mRNA amounts in extracellular vesicles (EVs) from plasma using a microfluidics device to enrich EVs. They show this method allows for the correlation of specific mRNAs with acute ischemic stroke pointing towards potential clinical use.

The etiology of thrombotic thrombocytopenic purpura (TTP), a severe blood disorder resulting from increased platelet activation, has been an enigma. The identification of ADAMTS as a protease that cleaves von Willebrand factor and the demonstration of ADAMTS mutations in families with inherited TTP suggest a molecular mechanism for the disease.

Complex combinations of simultaneous stimuli control cellular responses, and cross-talk between signaling pathways makes it even more difficult to predict these responses. Chatterjee et al. demonstrate in human platelets that neural networks trained with measurements of pairwise stimuli can predict combinations of many signaling inputs.