Recent progress on the biological functions of exosome-derived noncoding RNAs (exo-ncRNAs) in liver diseases is discussed in this review. Exo-ncRNAs are involved in the initiation and progression of liver diseases by regulating hepatic lipid metabolism, internal immunity, viral infection, fibrosis, biliary atresia and cancer. Exo-ncRNAs have clinical implications as promising biomarkers and therapeutic targets, especially for non-invasive diagnosis.
- Zhe Wen Zhou
- Wei Zheng
- Ke Yang Xu