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Large-scale proteomic analyses of incident Parkinson’s disease reveal new pathophysiological insights and potential biomarkers

The early pathophysiology of Parkinson’s disease is not well understood. Here the authors perform large-scale proteomic analyses of incident Parkinson’s disease to reveal pathophysiological insights and potential biomarkers, providing targets for early disease detection and guiding targeted therapeutic strategies.

Yi-Han Gan
Ling-Zhi Ma
Jin-Tai Yu
Research20 Feb 2025
Nature Aging

Volume: 5, P: 642-657
CaM promotes cardiomyocyte mitophagy in myocardial ischemia-reperfusion injury involving in the regulation of the IP3R3-GRP75-VDAC1 complex

Bi-Ying Liu
Zhao-Hui Dai
Zhong-Bao Yang
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Interleukin-13 interferes with activation-induced t-cell apoptosis by repressing p53 expression

Li Yang
Ling-Zhi Xu
Ping-Chang Yang
Research20 Jul 2015
Cellular & Molecular Immunology

Volume: 13, P: 669-677
The relationship between thyroid dysfunction and nephrotic syndrome: a clinicopathological study

Ling-Zhi Li
Yao Hu
Ping Fu
ResearchOpen Access23 Apr 2019
Scientific Reports

Volume: 9, P: 1-7
Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells

Bo Yang
Lin-Jing Li
Ping-Chang Yang
ResearchOpen Access22 Feb 2016
Scientific Reports

Volume: 6, P: 1-7
Chromodomain Y‐like (CDYL) inhibition ameliorates acute kidney injury in mice by regulating tubular pyroptosis

Ting Xiang
Ling-zhi Li
Ping Fu
Research23 Jul 2024
Acta Pharmacologica Sinica

Volume: 45, P: 2598-2610
Susceptibility of influenza A(H1N1)/pdm2009, seasonal A(H3N2) and B viruses to Oseltamivir in Guangdong, China between 2009 and 2014

Shan-shan Liu
Xiao-yang Jiao
Ping Xiong
ResearchOpen Access16 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Clinical utility of cerebrospinal fluid Alzheimer’s disease biomarkers in the diagnostic workup of complex patients with cognitive impairment

Ming-Yu Wang
Ke-Liang Chen
Jin-Tai Yu
ResearchOpen Access07 Apr 2025
Translational Psychiatry

Volume: 15, P: 1-10
Correction: EphB2 in the medial prefrontal cortex regulates vulnerability to stress

Ruo-Xi Zhang
Ying Han
Lin Lu
Amendments and Corrections19 Mar 2019
Neuropsychopharmacology

Volume: 44, P: 1339-1343
Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway

Li Wen
Shao-hua Tao
Ping Fu
Research22 Dec 2021
Acta Pharmacologica Sinica

Volume: 43, P: 2067-2080
Protective effect of salidroside against bone loss via hypoxia-inducible factor-1α pathway-induced angiogenesis

Ling Li
Ye Qu
Ling Zhi Li
ResearchOpen Access25 Aug 2016
Scientific Reports

Volume: 6, P: 1-16
Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects

Ying Han
Cheng-Yu Sun
Jie Shi
Research02 Aug 2019
Molecular Psychiatry

Volume: 25, P: 1260-1274
Author Correction: Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells

Bo Yang
Lin-Jing Li
Ping-Chang Yang
Amendments and CorrectionsOpen Access11 May 2021
Scientific Reports

Volume: 11, P: 1-2
Deficiency of Mkrn2 causes abnormal spermiogenesis and spermiation, and impairs male fertility

Xu Qian
Lin Wang
Bing-Hua Jiang
ResearchOpen Access23 Dec 2016
Scientific Reports

Volume: 6, P: 1-11
Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis

Xin Ge
Min-Hong Pan
Bing-Hua Jiang
ResearchOpen Access13 Nov 2018
Cell Death & Disease

Volume: 9, P: 1-16
IGF-1-mediated PKM2/β-catenin/miR-152 regulatory circuit in breast cancer

Yi-Yang Wen
Wei-Tao Liu
Bing-Hua Jiang
ResearchOpen Access21 Nov 2017
Scientific Reports

Volume: 7, P: 1-10
Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood

Jia-Hui Deng
Wei Yan
Lin Lu
ResearchOpen Access10 Aug 2017
Scientific Reports

Volume: 7, P: 1-15
EphB2 in the Medial Prefrontal Cortex Regulates Vulnerability to Stress

Ruo-Xi Zhang
Ying Han
Lin Lu
Research22 Apr 2016
Neuropsychopharmacology

Volume: 41, P: 2541-2556

Search

Large-scale proteomic analyses of incident Parkinson’s disease reveal new pathophysiological insights and potential biomarkers

CaM promotes cardiomyocyte mitophagy in myocardial ischemia-reperfusion injury involving in the regulation of the IP3R3-GRP75-VDAC1 complex

Interleukin-13 interferes with activation-induced t-cell apoptosis by repressing p53 expression

The relationship between thyroid dysfunction and nephrotic syndrome: a clinicopathological study

Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells

Chromodomain Y‐like (CDYL) inhibition ameliorates acute kidney injury in mice by regulating tubular pyroptosis

Susceptibility of influenza A(H1N1)/pdm2009, seasonal A(H3N2) and B viruses to Oseltamivir in Guangdong, China between 2009 and 2014

Clinical utility of cerebrospinal fluid Alzheimer’s disease biomarkers in the diagnostic workup of complex patients with cognitive impairment

Correction: EphB2 in the medial prefrontal cortex regulates vulnerability to stress

Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway

Protective effect of salidroside against bone loss via hypoxia-inducible factor-1α pathway-induced angiogenesis

Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects

Author Correction: Histone acetyltransferease p300 modulates TIM4 expression in dendritic cells

Deficiency of Mkrn2 causes abnormal spermiogenesis and spermiation, and impairs male fertility

Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis

IGF-1-mediated PKM2/β-catenin/miR-152 regulatory circuit in breast cancer

Predictable Chronic Mild Stress during Adolescence Promotes Fear Memory Extinction in Adulthood

EphB2 in the Medial Prefrontal Cortex Regulates Vulnerability to Stress

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