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Advanced filters: Author: Lixin Kan Clear advanced filters

High-yield porphyrin production through metabolic engineering and biocatalysis

Porphyrins are produced at scale through metabolic engineering and optimization of CPIII purification.

Haihong Chen
Yaohong Wang
Lixin Zhang
Research05 Jun 2024
Nature Biotechnology

P: 1-11
A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

Thermophilic genetic manipulation tools are limited. Here the authors report a thermophilic type I-B CRISPR-Cas system and show it displays efficient transcriptional repression or DNA cleavage activity: they develop a tool for genome editing and transcriptional repression in both thermophile and mesophile hosts.

Zhiheng Yang
Zilong Li
Weishan Wang
ResearchOpen Access04 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Inhibition of immune checkpoints prevents injury-induced heterotopic ossification

Chen Kan
Jiazhao Yang
Lixin Kan
ResearchOpen Access01 Nov 2019
Bone Research

Volume: 7, P: 1-8
Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis

B. Kim Lee Sim
Minglin Li
Stephen L. Hoffman
ResearchOpen Access15 Jun 2017
npj Vaccines

Volume: 2, P: 1-7

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