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Showing 51–100 of 199 results

Advanced filters: Author: Luis Blanco Clear advanced filters

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

Cancer therapy using systemically administrated 4-1BB-targeting antibodies is often associated with severe toxicity due to the nonspecific activation of autoreactive T cells. Here, the authors have developed a trimeric antibody targeting both 4-1BB and EGFR, which activates T cells effectively and shows negligible cytotoxicity.

Marta Compte
Seandean Lykke Harwood
Luis Alvarez-Vallina
ResearchOpen Access15 Nov 2018
Nature Communications

Volume: 9, P: 1-13
Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort

Rebeca Guillén
Fátima Otero
José Luis Fernández
ResearchOpen Access05 Aug 2021
Scientific Reports

Volume: 11, P: 1-6
Comparison Of Mechanical And Chemical Nanocellulose As Additives To Reinforce Recycled Cardboard

Jose Luis Sanchez-Salvador
Ana Balea
Angeles Blanco
ResearchOpen Access02 Mar 2020
Scientific Reports

Volume: 10, P: 1-14
TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol

Single cell genomic analysis needs DNA amplification with high fidelity and accuracy. Here, the authors devise a novel multiple displacement amplification method called TruePrime that is based in Thermus thermophilusPrimPol and Phi29 DNA polymerase, and demonstrate its utility and accuracy.

Ángel J. Picher
Bettina Budeus
Armin Schneider
ResearchOpen Access29 Nov 2016
Nature Communications

Volume: 7, P: 1-16
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

Thyroid hormones are well known to regulate whole-body energy metabolism, which was believed to occur as a direct effect on individual cells in the periphery. But Antonio Vidal-Puig and his colleagues now show that these thyroid hormone effects on energy regulation are actually indirect, as they regulate AMPK activity in the hypothalamus and thus central signaling to brown adipose tissue in the periphery.

Miguel López
Luis Varela
Antonio Vidal-Puig
Research29 Aug 2010
Nature Medicine

Volume: 16, P: 1001-1008
Laser-induced breakdown spectroscopy (LIBS) as a novel technique for detecting bacterial infection in insects

Nabil Killiny
Ed Etxeberria
Luis Ponce Cabrera
ResearchOpen Access21 Feb 2019
Scientific Reports

Volume: 9, P: 1-7
Human PrimPol activity is enhanced by RPA

María I. Martínez-Jiménez
Antonio Lahera
Luis Blanco
ResearchOpen Access10 Apr 2017
Scientific Reports

Volume: 7, P: 1-8
Microbead-based spoligotyping of Mycobacterium tuberculosis from Ziehl-Neelsen-stained microscopy preparations in Ethiopia

Barbara Molina-Moya
Mulualem Agonafir
Christophe Sola
ResearchOpen Access05 Mar 2018
Scientific Reports

Volume: 8, P: 1-6
Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis

Raquel López-Mejías
Fernanda Genre
Miguel A. González-Gay
ResearchOpen Access18 Aug 2016
Scientific Reports

Volume: 6, P: 1-7
Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis

Raquel López-Mejías
Alfonso Corrales
Miguel A. González-Gay
ResearchOpen Access06 Jan 2017
Scientific Reports

Volume: 7, P: 1-6
A rich population of free-floating planets in the Upper Scorpius young stellar association

A population of free-floating planets in Upper Scorpius that is larger than that predicted by core-collapse models suggests that the ejection of planets due to dynamical interactions early in the lifetime of a forming planetary system is more common than prevoiusly thought.

Núria Miret-Roig
Hervé Bouy
Nuria Huélamo
Research22 Dec 2021
Nature Astronomy

Volume: 6, P: 89-97
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Repriming of DNA synthesis at stalled replication forks by human PrimPol

DNA damage that causes replication forks to stall can be bypassed via translesion synthesis (TLS). New work has identified a bifunctional human primase and TLS polymerase, PrimPol, that reinitiates DNA synthesis beyond the damage site by virtue of its unique primase activity, revealing a novel pathway of DNA-damage tolerance.

Silvana Mourón
Sara Rodriguez-Acebes
Juan Méndez
Research17 Nov 2013
Nature Structural & Molecular Biology

Volume: 20, P: 1383-1389
Determinants of antibody levels and protection against omicron BQ.1/XBB breakthrough infection

Pérez et al. evaluate whether antibody levels and neutralization titers correlate with protection against SARS-CoV-2, including Omicron sub-variants BQ.1 and XBB, in a cohort of Spanish healthcare workers. They find an association that wanes over time, highlighting the need for updated vaccination strategies.

Carla Martín Pérez
Anna Ramírez-Morros
Carlota Dobaño
ResearchOpen Access20 Jun 2025
Communications Medicine

Volume: 5, P: 1-13
Timing and duration of calorie restriction determine its impact on ovarian aging in female mice

Juliane B. Prosczek
Jéssica D. Hense
Augusto Schneider
ResearchOpen Access09 Oct 2025
npj Aging

Volume: 11, P: 1-8
Obligatory steps in protein folding and the conformational diversity of the transition state

Jose C. Martinez
M. Teresa Pisabarro
Luis Serrano
Research01 Aug 1998
Nature Structural Biology

Volume: 5, P: 721-729
Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity

Genetic and Structural analysis of COVID patients cohort reveals a correlation between mitochondrial haplogroup and SARS-CoV-2 severity.

José Luis Cabrera-Alarcon
Raquel Cruz
José Antonio Enriquez
ResearchOpen Access09 Jan 2025
Communications Biology

Volume: 8, P: 1-12
Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis

Diana Prieto-Peña
Sara Remuzgo-Martínez
Raquel López-Mejías
ResearchOpen Access09 Aug 2021
Scientific Reports

Volume: 11, P: 1-8
Nesfatin-1-Like Peptide Encoded in Nucleobindin-1 in Goldfish is a Novel Anorexigen Modulated by Sex Steroids, Macronutrients and Daily Rhythm

Lakshminarasimhan Sundarrajan
Ayelén Melisa Blanco
Suraj Unniappan
ResearchOpen Access22 Jun 2016
Scientific Reports

Volume: 6, P: 1-14
BAFF, APRIL and BAFFR on the pathogenesis of Immunoglobulin-A vasculitis

Diana Prieto-Peña
Fernanda Genre
Raquel López-Mejías
ResearchOpen Access01 Jun 2021
Scientific Reports

Volume: 11, P: 1-7
A frameshift insertion in the cone cyclic nucleotide gated cation channel causes complete achromatopsia in a consanguineous family from a rural isolate

Cecilia V Rojas
Lorena Santa María
María Angélica Alliende
Research02 Oct 2002
European Journal of Human Genetics

Volume: 10, P: 638-642
A cancer-associated point mutation disables the steric gate of human PrimPol

Alberto Díaz-Talavera
Patricia A. Calvo
Luis Blanco
ResearchOpen Access04 Feb 2019
Scientific Reports

Volume: 9, P: 1-13
Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

Alfredo Guillén-Del-Castillo
Manuel López Meseguer
José Antonio Vargas Hitos
ResearchOpen Access28 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
An engineered HIV-1 Gag-based VLP displaying high antigen density induces strong antibody-dependent functional immune responses

Ferran Tarrés-Freixas
Carmen Aguilar-Gurrieri
Julià Blanco
ResearchOpen Access06 Apr 2023
npj Vaccines

Volume: 8, P: 1-13
Coevolution of visual behaviour, the material world and social complexity, depicted by the eye-tracking of archaeological objects in humans

Felipe Criado-Boado
Diego Alonso-Pablos
Luis M. Martínez
ResearchOpen Access08 Mar 2019
Scientific Reports

Volume: 9, P: 1-11
Patients’ and professionals’ preferences in terms of the attributes of home enteral nutrition products in Spain. A discrete choice experiment

Gabriel Olveira
Miguel Ángel Martínez-Olmos
Irmina Gozalbo
ResearchOpen Access20 Dec 2017
European Journal of Clinical Nutrition

Volume: 72, P: 272-280
Discovering HIV related information by means of association rules and machine learning

Lourdes Araujo
Juan Martinez-Romo
Pablo Telleria
ResearchOpen Access28 Oct 2022
Scientific Reports

Volume: 12, P: 1-12
Decoding the Peruvian Amazon with in situ DNA barcoding of vertebrate and plant taxa

Pamela Sánchez-Vendizú
Gideon Erkenswick
Mrinalini Watsa
ResearchOpen Access01 Oct 2025
Scientific Data

Volume: 12, P: 1-15
Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality.

Luis A. Pérez-Jurado
Alejandro Cáceres
Juan R. González
ResearchOpen Access19 Feb 2024
Communications Biology

Volume: 7, P: 1-14
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription

Aragón and colleagues show that the phosphatase Cdc14 acts on the CDT subunit of RNA polymerase II to silence transcription of repetitive regions of the yeast genome. At telomeres this event promotes condensin loading and mitotic segregation.

Andres Clemente-Blanco
Nicholas Sen
Luis Aragón
Research23 Oct 2011
Nature Cell Biology

Volume: 13, P: 1450-1456
Virological outcome among HIV infected patients transferred from pediatric care to adult units in Madrid, Spain (1997–2017)

Carolina Beltrán-Pavez
Miguel Gutiérrez-López
Elisa Lazzari
ResearchOpen Access09 Oct 2020
Scientific Reports

Volume: 10, P: 1-13
Personalized federated learning for predicting disability progression in multiple sclerosis using real-world routine clinical data

Ashkan Pirmani
Edward De Brouwer
Yves Moreau
ResearchOpen Access24 Jul 2025
npj Digital Medicine

Volume: 8, P: 1-15
A machine learning approach to identify patients at risk for long-term consequences after pulmonary embolism

Stephan Nopp
Clemens Spielvogel
H. M. Bui
ResearchOpen Access24 Sept 2025
Scientific Reports

Volume: 15, P: 1-12
A look at the Spanish film industry and its level of persistence

Francisco José Gil-Ruiz
Luis Alberiko Gil-Alana
Raquel Ayestarán-Crespo
ResearchOpen Access05 Jan 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
The BRAINTEASER Datasets: Clinical, Wearable and Environmental Data for ALS & MS Progression Modeling

Guglielmo Faggioli
Laura Menotti
Nicola Ferro
ResearchOpen Access21 Nov 2025
Scientific Data

Volume: 12, P: 1-15
Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains

Ana Alvarez-Cienfuegos
Natalia Nuñez-Prado
Luis Alvarez-Vallina
ResearchOpen Access27 Jun 2016
Scientific Reports

Volume: 6, P: 1-14
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
p38γ is essential for cell cycle progression and liver tumorigenesis

The stress-activated kinase p38γ has a role in regulating entry into the cell cycle; in the liver, it can induce cellular proliferation during regeneration and promote the development of hepatocellular carcinoma.

Antonia Tomás-Loba
Elisa Manieri
Guadalupe Sabio
Research10 Apr 2019
Nature

Volume: 568, P: 557-560
The heterogeneity of reversion to normoglycemia according to prediabetes type is not explained by lifestyle factors

Carolina Giráldez-García
Lucía Cea-Soriano
Carmen Yuste
ResearchOpen Access06 May 2021
Scientific Reports

Volume: 11, P: 1-11
Heterogeneity in the association between prediabetes categories and reduction on glomerular filtration rate in a 5-year follow-up

Marjan Manouchehri
Lucía Cea-Soriano
Pedro Muñoz
ResearchOpen Access05 May 2022
Scientific Reports

Volume: 12, P: 1-10
Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors

Miguel Sampedro-Núñez
Ana Serrano-Somavilla
Mónica Marazuela
ResearchOpen Access13 Dec 2018
Scientific Reports

Volume: 8, P: 1-11
Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif

Luis M. Molinos-Albert
Eneritz Bilbao
Julià Blanco
ResearchOpen Access13 Jan 2017
Scientific Reports

Volume: 7, P: 1-15
Impact of HIV infection and integrase strand transfer inhibitors-based treatment on the gut virome

Pablo Villoslada-Blanco
Patricia Pérez-Matute
José A. Oteo
ResearchOpen Access15 Dec 2022
Scientific Reports

Volume: 12, P: 1-11
Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

Pilar Redondo
Jesús Prieto
Guillermo Montoya
Research06 Nov 2008
Nature

Volume: 456, P: 107-111
Targeted gold-coated iron oxide nanoparticles for CD163 detection in atherosclerosis by MRI

Carlos Tarin
Monica Carril
Jesus Egido
ResearchOpen Access30 Nov 2015
Scientific Reports

Volume: 5, P: 1-9
Quantitative HDL Proteomics Identifies Peroxiredoxin-6 as a Biomarker of Human Abdominal Aortic Aneurysm

Elena Burillo
Inmaculada Jorge
Jose Luis Martin-Ventura
ResearchOpen Access09 Dec 2016
Scientific Reports

Volume: 6, P: 1-11
How carbohydrates sculpt cells: chemical control of morphogenesis in the yeast cell wall

In budding yeast, growth at the neck region connecting the mother and daughter cell is prevented by a septin ring inside the cell membrane and a chitin ring in the cell wall. Cabib and Arroyo describe recent work supporting the hypothesis that the attachment of the chitin ring to β-1,3-glucan is crucial for the control of morphogenesis at the neck.

Enrico Cabib
Javier Arroyo
Reviews16 Aug 2013
Nature Reviews Microbiology

Volume: 11, P: 648-655
COVID-19 clinical phenotypes in vaccinated and nonvaccinated solid organ transplant recipients: a multicenter validation study

Carmen Infante-Domínguez
Sonsoles Salto-Alejandre
Alice Toschi
ResearchOpen Access03 Dec 2024
Scientific Reports

Volume: 14, P: 1-13
A formal analysis of Listeria monocytogenes cross-contamination dynamics in multi-species biofilms

Raquel A. Nogueira
Juan J. Rodríguez-Herrera
Marta L. Cabo
ResearchOpen Access08 Aug 2025
npj Science of Food

Volume: 9, P: 1-11
An overview of Agaricus section Hondenses and Agaricus section Xanthodermatei with description of eight new species from Pakistan

Hira Bashir
Jie Chen
Philippe Callac
ResearchOpen Access18 Jun 2021
Scientific Reports

Volume: 11, P: 1-35

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