Azobenzene-based photoswitchable drugs traditionally require activation with UV-blue light having poor tissue penetration. Here, the authors show triplet sensitized photoisomerization of an azo drug with far-red and NIR light, allowing deep tissue penetration and in vivo heart rate control in frog tadpoles.
- Lukas Naimovičius
- Mila Miroshnichenko
- Kasper Moth-Poulsen