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Showing 1–50 of 55 results

Advanced filters: Author: M Daher Clear advanced filters

Simplexifying sustainability

How can sustainability science avoid paralysis in the face of complexity and ensure it catalyses meaningful action? The key lies in practising the science and art of simplexity, argues Bassel Daher.

Bassel Daher
Comments & Opinion29 Sept 2025
Nature Sustainability

P: 1-2
CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells

The transcription factor CREM is a pivotal regulator of NK cell function, making CREM a valuable target to increase the efficacy of anticancer immunotherapies based on this cell population and chimeric antigen receptors.

Hind Rafei
Rafet Basar
Katayoun Rezvani
ResearchOpen Access04 Jun 2025
Nature

Volume: 643, P: 1076-1086
Plasticity and redundancy among AMA–RON pairs ensure host cell entry of Toxoplasma parasites

Apicomplexan parasites such as Toxoplasma gondii and Plasmodium form a tight, moving junction with host cells before invading them. Here the authors show that the proteins AMA1 and RON2 of T. gondiicooperate during junction formation and identify additional proteins that have a role in this process.

Mauld H. Lamarque
Magali Roques
Maryse Lebrun
Research17 Jun 2014
Nature Communications

Volume: 5, P: 1-13
The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites

HDP1 is a novel DNA-binding protein that functions as a positive transcriptional regulator of genes that gives Plasmodium falciparum gametocytes their characteristic ‘banana’ shape.

Riward A. Campelo Morillo
Xinran Tong
Björn F. C. Kafsack
Research27 Jan 2022
Nature Microbiology

Volume: 7, P: 289-299
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia

Notch1 is frequently activated promoting T-cell acute lymphoblastic leukaemia (T-ALL). Here, the authors show that Notch1 induces oxidative phosphorylation dependency in T-ALL and synergism when inhibiting both mitochondrial complex I and glutaminolysis in preclinical murine and human xenograft models.

Natalia Baran
Alessia Lodi
Marina Konopleva
ResearchOpen Access19 May 2022
Nature Communications

Volume: 13, P: 1-20
Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection

Herpes simplex virus 1 (HSV-1) is a neurotropic virus that often cause pain via the induction of ulcer or blisters. Here the authors show, in mouse models of HSV-1 infection, that the pain-perceiving nociceptor Nav_1.8⁺ neurons contribute to regulating both innate and adaptive immune responses against HSV-1, thereby offering a potential target for therapy.

Jessica Filtjens
Anais Roger
Sophie Ugolini
ResearchOpen Access18 May 2021
Nature Communications

Volume: 12, P: 1-15
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Mutations in LSM11 and RNU7-1, which encode components of the replication-dependent histone pre-mRNA–processing complex, cause an autoinflammatory syndrome due to enhanced interferon signaling mediated by the cGAS–STING pathway, showing an essential role for nuclear histones in suppressing the immunogenicity of self-DNA.

Carolina Uggenti
Alice Lepelley
Yanick J. Crow
Research23 Nov 2020
Nature Genetics

Volume: 52, P: 1364-1372
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
Compression force sensing regulates integrin α_IIbβ₃ adhesive function on diabetic platelets

Diabetes is associated with an increased thrombotic response, but the mechanism is unknown. Here the authors demonstrate that compressive force activates integrin α_IIbβ₃ on discoid diabetic platelets and that platelet aggregates can be eliminated by PI 3-kinase inhibition, but not by anti-thrombotics aspirin or clopidogrel.

Lining Ju
James D. McFadyen
Shaun P. Jackson
ResearchOpen Access14 Mar 2018
Nature Communications

Volume: 9, P: 1-16
The responses of HNSCC patients to immunotherapy are shown by two novel co-expression patterns

Narmeen Daher-Ghanem
Shay Sharon
Nataly Kravchenko-Balasha
ResearchOpen Access01 Jul 2025
npj Precision Oncology

Volume: 9, P: 1-10
High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control

Factors underlying the effects of gastric bypass surgery on glucose homeostasis are incompletely understood. Here the authors developed and applied high-throughput mediation analysis to identify proteome/metabolome mediators of improved glucose homeostasis after to gastric bypass surgery, and report that improved glycemia was mediated by the growth hormone receptor.

Jonathan M. Dreyfuss
Yixing Yuchi
Mary Elizabeth Patti
ResearchOpen Access29 Nov 2021
Nature Communications

Volume: 12, P: 1-13
Patients’ intention to make an up-front payment at private outpatient clinics in Malaysia as a no-show reduction method

Aqil M. Daher
Nitiyanantam Perremal
Adlina Suleiman
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-8
The effect of anteromedian sphincterotomy on penile erections in patients with neuropathic bladder

N H Philp
D G Thomas
A M K Rickwood
Research01 Oct 1983
Spinal Cord

Volume: 21, P: 301-304
Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways

Bukhtiar H Shah
A Siddiqui
S A Saeed
ResearchOpen Access01 Mar 1999
Experimental & Molecular Medicine

Volume: 31, P: 42-46
Pathological conditions obscured by paraplegia

G M Pool
Research01 Feb 1984
Spinal Cord

Volume: 22, P: 27-30
Health literacy-related knowledge, attitude, perceived barriers, and practice among primary care doctors in Malaysia

Mohamed-Syarif Mohamed-Yassin
Aqil M. Daher
Noorhida Baharudin
ResearchOpen Access13 Nov 2023
Scientific Reports

Volume: 13, P: 1-9
Fatal basilar artery occlusion following cervical spine injury

Robert M Woolsey
Hyung D Chung
Research01 Sept 1979
Spinal Cord

Volume: 17, P: 280-283
Fear of progression, coping strategies, and associated factors among a sample of Malaysian women with breast cancer

Hui Li Lim
Mohammed K. Suhail
Aqil M. Daher
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-8
Morbidity after accelerated enhanced recovery protocol for colon cancer surgery

Misha A. T. Sier
Sarah L. Dekkers
Jan H. M. B. Stoot
ResearchOpen Access19 Aug 2024
Scientific Reports

Volume: 14, P: 1-8
Publisher Correction: The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites

Riward A. Campelo Morillo
Xinran Tong
Björn F. C. Kafsack
Amendments and Corrections08 Feb 2022
Nature Microbiology

Volume: 7, P: 464
Vascular complications of selected cancer therapies

Vascular complications following cancer treatment are relatively common, particularly in patients with advanced stages of cancer. In this Review, Dr Daher and Dr Yeh describe the vascular complications of treatment with 5-fluorouracil, bevacizumab, and several new tyrosine kinase inhibitors, with special emphasis on thrombotic complications and hypertension.

Iyad N Daher
Edward TH Yeh
Reviews14 Oct 2008
Nature Clinical Practice Cardiovascular Medicine

Volume: 5, P: 797-805
The effect of reducing per capita water and energy uses on renewable water resources in the water, food and energy nexus

Shima Kheirinejad
Omid Bozorg-Haddad
Hugo A. Loáiciga
ResearchOpen Access09 May 2022
Scientific Reports

Volume: 12, P: 1-17
Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape

C Wiel
B Gras
D Bernard
Research15 Jun 2015
Oncogene

Volume: 35, P: 1596-1601
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Effect of viscous dissipation and induced magnetic field on an unsteady mixed convective stagnation point flow of a nonhomogenous nanofluid

M. A. Aiyashi
S. M. Abo-Dahab
M. Daher Albalwi
ResearchOpen Access18 Dec 2023
Scientific Reports

Volume: 13, P: 1-14
Mucinous differentiation features associated with hormonal escape in a human prostate cancer xenograft

M-E Legrier
G de Pinieux
M-F Poupon
ResearchOpen Access03 Feb 2004
British Journal of Cancer

Volume: 90, P: 720-727
Dynamics of chaotic system based on circuit design with Ulam stability through fractal-fractional derivative with power law kernel

Naveed Khan
Zubair Ahmad
Shao-Wen Yao
ResearchOpen Access28 Mar 2023
Scientific Reports

Volume: 13, P: 1-21
Acute stress promotes effort mobilization for safety-related goals

People who underwent acute stress tended to prioritize safety over effort minimization. This led stressed people to mobilize more effort than non-stressed people to avoid threats that have a low probability to occur.

Kristína Pavlíčková
Judith Gärtner
Dennis Hernaus
ResearchOpen Access01 Jun 2024
Communications Psychology

Volume: 2, P: 1-14
Tumour basement membrane laminin expression predicts outcome following curative resection of pancreatic head cancer

J A van der Zee
C HJ van Eijck
T LM ten Hagen
ResearchOpen Access28 Aug 2012
British Journal of Cancer

Volume: 107, P: 1153-1158
Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)

J Northover
R Glynne-Jones
J Ledermann
ResearchOpen Access16 Mar 2010
British Journal of Cancer

Volume: 102, P: 1123-1128
Differences in the expression of mucus-associated antigens between proximal and distal human colon adenocarcinomas

J Bara
J Nardelli
P Burtin
Research01 Apr 1984
British Journal of Cancer

Volume: 49, P: 495-501
Clinical relevance of MYC/BCL2 expression and cell of origin in patients with diffuse large b-cell lymphoma treated with autologous transplant

Taha Al-Juhaishi
Yingjun Wang
Issa F. Khouri
Research18 May 2023
Bone Marrow Transplantation

Volume: 58, P: 1000-1007
Accelerated 23-h enhanced recovery protocol for colon surgery: the CHASE-study

Thaís T. T. Tweed
Misha A. T. Sier
Jan H. M. B. Stoot
ResearchOpen Access01 Dec 2022
Scientific Reports

Volume: 12, P: 1-8
Impact of the Reticular Stress and Unfolded Protein Response on the inflammatory response in endometrial stromal cells

E. Grasso
S. Gori
R. Ramhorst
ResearchOpen Access16 Aug 2018
Scientific Reports

Volume: 8, P: 1-12
A phase II study of UFT with leucovorin administered as a twice daily schedule in the treatment of patients with metastatic colorectal cancer

P M Hoff
S Kopetz
J L Abbruzzese
ResearchOpen Access12 Aug 2008
British Journal of Cancer

Volume: 99, P: 722-726
One year follow-up on a randomized study investigating serratus anterior muscle and pectoral nerves type I block to reduced neuropathic pain descriptors after mastectomy

Eva M. Flores
Flavia V. Gouveia
Raquel C. R. Martinez
ResearchOpen Access21 Mar 2023
Scientific Reports

Volume: 13, P: 1-12
Id3 induces a caspase-3- and -9-dependent apoptosis and mediates UVB sensitization of HPV16 E6/7 immortalized human keratinocytes

C M Simbulan-Rosenthal
A Daher
D S Rosenthal
Research30 Jan 2006
Oncogene

Volume: 25, P: 3649-3660
Parenteral Selenium Supplementation in Extremely Low Birth Weight Infants: Inadequate Dosage But No Correlation With Hypothyroidism

Gil Klinger
Raanan Shamir
Lea Sirota
Research23 Dec 1999
Journal of Perinatology

Volume: 19, P: 568-572
Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody

Marc S. Raab
Yael C. Cohen
Haihui Lu
Research06 Apr 2023
Leukemia

Volume: 37, P: 1349-1360
Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

Christian Hausmann
Christian Zoschke
Monika Schäfer-Korting
ResearchOpen Access27 Feb 2019
Scientific Reports

Volume: 9, P: 1-10
Benefits in radical mastectomy protocol: a randomized trial evaluating the use of regional anesthesia

Marcio Matsumoto
Eva M. Flores
Raquel C. R. Martinez
ResearchOpen Access18 May 2018
Scientific Reports

Volume: 8, P: 1-9
Intermediate-conductance Ca²⁺-activated K⁺ channels (IK_Ca1) regulate human prostate cancer cell proliferation through a close control of calcium entry

H Lallet-Daher
M Roudbaraki
N Prevarskaya
Research09 Mar 2009
Oncogene

Volume: 28, P: 1792-1806
Estradiol and Progesterone have Opposing Roles in the Regulation of Fear Extinction in Female Rats

Bronwyn M Graham
Melissa Daher
Research09 Jul 2015
Neuropsychopharmacology

Volume: 41, P: 774-780
Monoclonal antibody FW6 generated against a mucin-carbohydrate of human amniotic fluid recognises a colonic tumour-associated epitope

M Schwonzen
R Schmits
G Uhlenbruck
Research01 Apr 1992
British Journal of Cancer

Volume: 65, P: 559-565
Aberrant expression of intestinal mucin antigens associated with colorectal carcinoma defined by a panel of monoclonal antibodies

PJ Hertzog
SJ Pilbrow
AW Linnane
Research01 Nov 1991
British Journal of Cancer

Volume: 64, P: 799-808
Nrf2-related gene expression and exposure to traffic-related air pollution in elderly subjects with cardiovascular disease: An exploratory panel study

Sharine Wittkopp
Norbert Staimer
Ralph J Delfino
Research07 Jan 2015
Journal of Exposure Science & Environmental Epidemiology

Volume: 26, P: 141-149
Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation

Cynthia M Simbulan-Rosenthal
Valerie Trabosh
Dean S Rosenthal
Research27 Jun 2005
Oncogene

Volume: 24, P: 5443-5458
Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway

K Kondo
H Shaim
K Rezvani
Research03 Oct 2017
Leukemia

Volume: 32, P: 960-970
Outcomes of toxoplasmosis after allogeneic hematopoietic stem cell transplantation and the role of antimicrobial prophylaxis

Alexandre E. Malek
Taha Al-Juhaishi
Sairah Ahmed
Correspondence14 Feb 2024
Bone Marrow Transplantation

Volume: 59, P: 699-704

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