Nature Search

Amino acid sequence of homogeneous antibodies to dextran and DNA rearrangments in heavy chain V-region gene segments

J. Schilling
B. Clevinger
L. Hood
Research03 Jan 1980
Nature

Volume: 283, P: 35-40
Translation of natural mRNAs in vitro by extracts of a mutant in protein synthesis

M. B. HERRINGTON
M. J. DOHERTY
M. C. GANOZA
Research21 Aug 1975
Nature

Volume: 256, P: 678-679
Fabrication and operation of a two-dimensional ion-trap lattice on a high-voltage microchip

Microfabricated ion traps offer a promising platform for scalable ion quantum computing systems. Sterling et al.realize a two-dimensional ion-trap lattice on a microchip using a new fabrication method that allows very-high voltages to be applied to the chip, enabling very deep ion traps.

R. C. Sterling
H. Rattanasonti
W. K. Hensinger
Research04 Apr 2014
Nature Communications

Volume: 5, P: 1-6
Morphology of iodine-doped polyacetylene

H. ROMMELMANN
R. FERNQUIST
T. WOERNER
Research14 Jul 1983
Nature

Volume: 304, P: 189
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor

Georgiou et al. found that the sex of the person performing experiments affects mouse behavior, including responses to stress and ketamine. This effect was mediated by corticotropin-releasing factor neurons in the entorhinal cortex that project to CA1.

Polymnia Georgiou
Panos Zanos
Todd D. Gould
Research30 Aug 2022
Nature Neuroscience

Volume: 25, P: 1191-1200
The preference for sugar over sweetener depends on a gut sensor cell

Buchanan, Rupprecht, Kaelberer and colleagues show that the preference for sugar over sweetener in mice depends on gut neuropod cells. Akin to other sensor cells, neuropod cells swiftly communicate the precise identity of stimuli to drive food choices.

Kelly L. Buchanan
Laura E. Rupprecht
Diego V. Bohórquez
ResearchOpen Access13 Jan 2022
Nature Neuroscience

Volume: 25, P: 191-200
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
A paradox in the control of energy intake in the rat

NANCY J. ROTHWELL
M. J. STOCK
Research11 May 1978
Nature

Volume: 273, P: 146-147
Circulating antibodies to the neuritogenic myelin protein, P₂ , in neuritis of the cauda equina of the horse

M. Kadlubowski
P. L. Ingram
Research24 Sept 1981
Nature

Volume: 293, P: 299-300
Myelin-associated glycoprotein in human retina

K. Stefansson
M. L. Molnar
D. P. Richman
Research09 Feb 1984
Nature

Volume: 307, P: 548-550
Nitrous oxide enhances MR-guided focused ultrasound delivery of gene therapy to the murine hippocampus

Deepshikha Bhardwaj
Ibrahim Youssef
Bhavya R. Shah
Research06 May 2025
Gene Therapy

Volume: 32, P: 376-384
Gene editing and elimination of latent herpes simplex virus in vivo

Herpes simplex virus establishes lifelong latency in ganglionic neurons, which are the source for recurrent infection. Here Aubert et al. report a promising antiviral therapy based on gene editing with adeno-associated virus-delivered meganucleases, which leads to a significant reduction in ganglionic HSV loads and HSV reactivation.

Martine Aubert
Daniel E. Strongin
Keith R. Jerome
ResearchOpen Access18 Aug 2020
Nature Communications

Volume: 11, P: 1-15
A near-infrared genetically encoded calcium indicator for in vivo imaging

A near-infrared fluorescent calcium indicator can be combined with other optogenetic tools in vivo without spectral crosstalk.

Anton A. Shemetov
Mikhail V. Monakhov
Vladislav V. Verkhusha
Research26 Oct 2020
Nature Biotechnology

Volume: 39, P: 368-377
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1

Compound MMV006833 inhibits ring-stage development of Plasmodium falciparum. Here, the authors show that it targets lipid transfer enzyme PfSTART1 and prevents PfSTART1 from expanding the vacuole membrane encasing the parasite after red blood cell invasion, thereby blocking parasite growth.

Madeline G. Dans
Coralie Boulet
Paul R. Gilson
ResearchOpen Access18 Jun 2024
Nature Communications

Volume: 15, P: 1-19
σ^± lifetimes and longitudinal acceleration

C. E. Roos
J. Marraffino
G. Wolf
Research17 Jul 1980
Nature

Volume: 286, P: 244-245
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

In this study, the authors report that pluripotent stem cell-derived ventricular progenitors target loss of myocardium and fibrotic scarring to promote heart regeneration, thus offering new potential therapeutic strategies for heart injury.

Christine M. Poch
Kylie S. Foo
Karl-Ludwig Laugwitz
ResearchOpen Access12 May 2022
Nature Cell Biology

Volume: 24, P: 659-671
A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

A microbiome-focused metabolomics pipeline and interactive metabolomics profile explorer are a powerful tool for the characterization of gut-resident microorganisms and the interactions between microorganisms and their host.

Shuo Han
Will Van Treuren
Justin L. Sonnenburg
Research14 Jul 2021
Nature

Volume: 595, P: 415-420
A mutation in Caenorhabditis elegans that increases recombination frequency more than threefold

A. M. Rose
D. L. Baillie
Research01 Oct 1979
Nature

Volume: 281, P: 599-600
Randomised comparison of percutaneous angioplasty vs continued medical therapy for hypertensive patients with atheromatous renal artery stenosis

J Webster
F Marshall
R Wilkinson
Research10 Jun 1998
Journal of Human Hypertension

Volume: 12, P: 329-335
TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model

Tyrosine kinase 2 (TYK2) critically regulates tau levels and aggregation by phosphorylating tau’s tyrosine 29. Partial inhibition of TYK2 mitigates tau pathologies in cells and mice, highlighting TYK2 as a potential therapeutic target for Alzheimer’s disease and other tauopathies.

Jiyoen Kim
Bakhos Tadros
Huda Yahya Zoghbi
ResearchOpen Access11 Nov 2024
Nature Neuroscience

Volume: 27, P: 2417-2429
Cementing proteins provide extra mechanical stabilization to viral cages

Some viruses possess ‘decoration’ proteins, such as gpD in lambda phage, that stabilize the viral particles in poorly understood ways. Here the authors show that gpD incorporation into lambda particles provides mechanical reinforcement and increased resistance to punctual deformations and collisions.

M. Hernando-Pérez
S. Lambert
P. J. de Pablo
Research29 Jul 2014
Nature Communications

Volume: 5, P: 1-8
Postsynaptic control of plasticity in developing somatosensory cortex

Bradley L. Schlaggar
Kevin Fox
Dennis M. O'Leary
Research12 Aug 1993
Nature

Volume: 364, P: 623-626
Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis

Stress kinases are activated in peripheral ischemic tissues in the presence of vascular diseases. Here the authors show that inhibition of the neural JNK3 kinase improves recovery from hind limb ischemia in animals through activation of the transcription factors Egr1/Creb1 and upregulation of growth factors.

Shashi Kant
Siobhan M. Craige
John F. Keaney Jr.
ResearchOpen Access17 Sept 2019
Nature Communications

Volume: 10, P: 1-14
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Magnetic Properties in Relation to Chemical Constitution

T. M. LOWRY
F. L. GILBERT
Research19 Jan 1929
Nature

Volume: 123, P: 85
Target-based discovery of a broad-spectrum flukicide

The authors uncovered an antiparasitic molecule that exhibits broad-spectrum activity against parasitic flukes through engagement of a recently discovered transient receptor potential ion channel.

Daniel J. Sprague
Sang-Kyu Park
Jonathan S. Marchant
Research07 May 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1386-1393
The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility

Male mice lacking piRNAs from a conserved locus on chromosome 6 (pi6) produce sperm with defects in capacitation and egg fertilization. pi6 piRNAs repress mRNAs required for sperm function.

Pei-Hsuan Wu
Yu Fu
Phillip D. Zamore
Research29 Jun 2020
Nature Genetics

Volume: 52, P: 728-739
Confusion of Mirror Images by Pigeons and Interhemispheric Commissures

I. L. BEALE
R. J. WILLIAMS
M. C. CORBALLIS
Research11 Aug 1972
Nature

Volume: 238, P: 348-349
Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia

A personalized virtual-heart model that determines optimal radio-frequency ablation targets for infarct-related tachycardia is validated in retrospective large-animal and patient studies, and in a prospective study in patients.

Adityo Prakosa
Hermenegild J. Arevalo
Natalia A. Trayanova
Research03 Sept 2018
Nature Biomedical Engineering

Volume: 2, P: 732-740
APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence

Combinatorial experimental and bioinformatics methods can be used to analyse function and specificity of CD8 T cells. Here the authors propose a multiomic analysis framework Antigen-TCR Pairing and Multiomic Analysis of T cell (APMAT) to relate TCR specificity to transcriptomic phenotype indicating associations with physicochemical features.

Jingyi Xie
Daniel G. Chen
James R. Heath
ResearchOpen Access06 Feb 2025
Nature Communications

Volume: 16, P: 1-15
Cerium/lead and lead isotope ratios in arc magmas and the enrichment of lead in the continents

Daniel M. Miller
Steven L. Goldstein
Charles H. Langmuir
Research07 Apr 1994
Nature

Volume: 368, P: 514-520
Conversion of mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts

T. A. Partridge
J. E. Morgan
L. M. Kunkel
Research12 Jan 1989
Nature

Volume: 337, P: 176-179
Dynamics of plasmid-mediated niche invasion, immunity to invasion, and pheromone-inducible conjugation in the murine gastrointestinal tract

Microbial communities provide protection to their hosts by excluding colonizing pathogens. Here the authors study plasmid transfer and plasmid-mediated effects on host colonization and persistence of Enterococcus faecalis in the intestinal tract of mice.

Helmut Hirt
Kerryl E. Greenwood-Quaintance
Gary M. Dunny
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-10
Helminth-induced IL-4 expands bystander memory CD8⁺ T cells for early control of viral infection

Parasitic helminth infection is known to impact upon the host response to other bystander inflammatory processes. Here the authors show that IL4 production induced by helminth infection results in expansion of bystander CD8+ memory T cells and enhanced control to viral infection.

Marion Rolot
Annette M. Dougall
Benjamin G. Dewals
ResearchOpen Access30 Oct 2018
Nature Communications

Volume: 9, P: 1-16
Immunohistochemical localization of the cell adhesion molecules Thy-1 and L1 in the human prefrontal cortex: patients with schizophrenia, bipolar disorder, and depression

M J Webster
M P Vawter
W J Freed
Research22 Jan 1999
Molecular Psychiatry

Volume: 4, P: 46-52
Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

Samuel J McConkey
William H H Reece
Adrian V S Hill
Research25 May 2003
Nature Medicine

Volume: 9, P: 729-735
Deep learning-enabled realistic virtual histology with ultraviolet photoacoustic remote sensing microscopy

Oncologic tumour resection is not fully accurate. Here the authors report a label-free virtual histological imaging method based on a non-contact, reflection-mode ultraviolet photoacoustic remote sensing and scattering microscope, combined with unsupervised deep learning using a cycle-consistent GAN.

Matthew T. Martell
Nathaniel J. M. Haven
Roger J. Zemp
ResearchOpen Access25 Sept 2023
Nature Communications

Volume: 14, P: 1-17
Mapping T-cell receptor–peptide contacts by variant peptide immunization of single-chain transgenics

Jeffrey L. Jorgensen
Ursula Esser
Mark M. Davis
Research16 Jan 1992
Nature

Volume: 355, P: 224-230
Precipitating antibodies in von Willebrand's disease

P. M. MANNUCCI
DOMINIQUE MEYER
J.-M. LAVERGNE
Research01 Jul 1976
Nature

Volume: 262, P: 141-142
Effect of Lithium Ions on the Release of Acetylcholine from the Cerebral Cortex

M. BJEGOVIĆ
M. RANDIĆ
Research30 Apr 1971
Nature

Volume: 230, P: 587-588
3C390.3, a Second Variable N-Galaxy

R. D. CANNON
M. V. PENSTON
MARGARET J. PENSTON
Research27 Jan 1968
Nature

Volume: 217, P: 340-341
Monoclonal anti-Fc receptor IgG blocks antibody enhancement of viral replication in macrophages

J. S. M. Peiris
S. Gordon
J. S. Porterfield
Research15 Jan 1981
Nature

Volume: 289, P: 189-191
Pattern of Remyelination in the CNS

R. F. GLEDHILL
B. M. HARRISON
W. I. MCDONALD
Research17 Aug 1973
Nature

Volume: 244, P: 443-444
Orthotopic Heart Transplantation in the Pig

R. Y. CALNE
H. BITTER-SUERMANN
L. M. WEBSTER
Research18 Jan 1974
Nature

Volume: 247, P: 140-142
Effect of cell history on response to helix–loop–helix family of myogenic regulators

Beat W. Schäfer
Bruce T. Blakely
Helen M. Blau
Research29 Mar 1990
Nature

Volume: 344, P: 454-458
Another major change in the radio source associated with Cyg X-1

R. M. HJELLMING
D. M. GIBSON
F. N. OWEN
Research10 Jul 1975
Nature

Volume: 256, P: 111-112
Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

A. W. Ford-Hutchinson
M. A. Bray
M. J. H. Smith
Research17 Jul 1980
Nature

Volume: 286, P: 264-265
Refinement of pore size at sub-angstrom precision in robust metal–organic frameworks for separation of xylenes

Separation of xylene isomers is essential for the production of a wide range of materials, but current separation methods are energy intensive. Here the authors report separation of the three xylene isomers at room temperature, via refinement of the pore size in a series of porous MOFs at sub-angstrom precision.

Xiaolin Li
Juehua Wang
Martin Schröder
ResearchOpen Access27 Aug 2020
Nature Communications

Volume: 11, P: 1-10
Distribution of Temperature in the Skin of Sheep exposed to Moderate Environments

M. E. D. WEBSTER
K. G. JOHNSON
Research11 Jan 1964
Nature

Volume: 201, P: 208-209
Morphology of iodine-doped polyacetylene (reply)

M. ROLLAND
M. CADENE
Research14 Jul 1983
Nature

Volume: 304, P: 189-190

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