Sanchez-Fernandez, Lorda-Diez et al. study a possible link between DNA methylation and interdigital cell death. They use irradiation experiments, methylation, and mutagenic analyses to demonstrate that Dnmt3b inversely regulates cell death and cartilage differentiation. Their work provides insights on the regulation of apoptosis in embryonic limbs.
- Cristina Sanchez-Fernandez
- Carlos Ignacio Lorda-Diez
- Juan Antonio Montero