Nature Search

A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites

Apical membrane antigen-1 (AMA1) is important for Plasmodium parasite invasion, but surface polymorphisms in P. falciparum AMA1 hamper vaccine and antibody development. Here the authors identify a humanised single-domain antibody molecule, an i-body, that binds to AMA1 of all Plasmodium parasites examined and inhibits parasite invasion.

Dimuthu Angage
Jill Chmielewski
Michael Foley
ResearchOpen Access22 Aug 2024
Nature Communications

Volume: 15, P: 1-17
Perceptual interference supports a non-modular account of face processing

Isabel Gauthier
Tim Curran
Daniel Collins
Research10 Mar 2003
Nature Neuroscience

Volume: 6, P: 428-432
Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon

Jordan S. Pober
Tucker Collins
Carol S. Reiss
Research20 Oct 1983
Nature

Volume: 305, P: 726-729
A radiation hybrid map of 506 STS markers spanning human chromosome 11

M.R. James
C.W. Richard III
G.M. Lathrop
Research01 Sept 1994
Nature Genetics

Volume: 8, P: 70-76
New mdx mutation disrupts expression of muscle and nonmuscle isoforms of dystrophin

Gregory A. Cox
Stephanie F. Phelps
Jeffrey S. Chamberlain
Research01 May 1993
Nature Genetics

Volume: 4, P: 87-93
Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity

Antibody-mediated depletion of myeloid-biased haematopoietic stem cells in aged mice restores characteristic features of a more youthful immune system.

Jason B. Ross
Lara M. Myers
Irving L. Weissman
Research27 Mar 2024
Nature

Volume: 628, P: 162-170
Correction of feline arylsulphatase B deficiency (mucopolysaccharidosis VI) by bone marrow transplantation

P. W. Gasper
M. A. Thrall
E. A. Hoover
Research29 Nov 1984
Nature

Volume: 312, P: 467-469
Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

Guy A. Rouleau
Philippe Merel
Gilles Thomas
Research10 Jun 1993
Nature

Volume: 363, P: 515-521
Relationship between spreading rate and the seismic structure of mid-ocean ridges

G. M. Purdy
L. S. L. Kong
S. C. Solomon
Research27 Feb 1992
Nature

Volume: 355, P: 815-817
Genome-wide association study and functional characterization identifies candidate genes for insulin-stimulated glucose uptake

Genome-wide association analyses of two oral glucose tolerance test-derived measures of postprandial insulin resistance discover ten new loci. Functional characterization identifies nine candidate genes implicated in the regulation of GLUT4.

Alice Williamson
Dougall M. Norris
Claudia Langenberg
Research08 Jun 2023
Nature Genetics

Volume: 55, P: 973-983
Measurement of the inelastic proton–proton cross-section at √s=7 TeV with the ATLAS detector

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access06 Sept 2011
Nature Communications

Volume: 2, P: 1-14
Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Experiments at the Joint European Torus tokamak show improved thermal ion confinement in the presence of highly energetic ions and Alfvénic instabilities in the plasma.

S. Mazzi
J. Garcia
I. Zychor
Research30 Jun 2022
Nature Physics

Volume: 18, P: 776-782
Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis

Nikolai A. Lisitsyn
Julia A. Segre
Eric S. Lander
Research01 Jan 1994
Nature Genetics

Volume: 6, P: 57-63
Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer

‘T cell engagers promote antitumor immunity, but how macrophage modulates this activity in tumor is still unclear. Here the authors show, using biopsies from patients with uveal melanoma and single cell analyses, that a T cell engager, tebentafusp, reprograms tumor-associated macrophages and ameliorates, in synergy with IL-2, immunosuppression to cancer.

Esra Güç
Agatha Treveil
Adel Benlahrech
ResearchOpen Access10 Mar 2025
Nature Communications

Volume: 16, P: 1-16
Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence

David D. Roberts
James A. Sherwood
Victor Ginsburg
Research01 Nov 1985
Nature

Volume: 318, P: 64-66
A multi-species synthesis of physiological mechanisms in drought-induced tree mortality

The mechanisms underlying drought-induced tree mortality are not fully resolved. Here, the authors show that, across multiple tree species, loss of xylem conductivity above 60% is associated with mortality, while carbon starvation is not universal.

Henry D. Adams
Melanie J. B. Zeppel
Nate G. McDowell
Research07 Aug 2017
Nature Ecology & Evolution

Volume: 1, P: 1285-1291
Overcoming conduction failure in demyelinated nerve fibres by prolonging action potentials

H. BOSTOCK
R. M. SHERRATT
T. A. SEARS
Research27 Jul 1978
Nature

Volume: 274, P: 385-387
Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8

Samuel E. Lux
William T. Tse
Bernard G. Forget
Research21 Jun 1990
Nature

Volume: 345, P: 736-739
γ Endorphin, α endorphin and Met-enkephalin are formed extracellularly from lipotropin C fragment

B. M. AUSTEN
D. G. SMYTH
C. R. SNELL
Research01 Oct 1977
Nature

Volume: 269, P: 619-621
Divergent B-cell repertoire remodelling by mRNA, DNA and live attenuated vaccines in fish

Dean Porter
Catherine Collins
Pierre Boudinot
ResearchOpen Access24 Jul 2025
npj Vaccines

Volume: 10, P: 1-16
Spin caloritronic nano-oscillator

Harvesting ohmic heat for signal processing is one of major challenges in modern electronics and spin caloritronics, but not yet well accomplished. Here the authors demonstrate a spin torque oscillator device driven by pure spin current arising from thermal gradient across an Y₃Fe₅O₁₂/Pt interface.

C. Safranski
I. Barsukov
I. N. Krivorotov
ResearchOpen Access18 Jul 2017
Nature Communications

Volume: 8, P: 1-7
Correlation of Ant Alarm Pheromone Activity with Molecular Vibration

R. H. WRIGHT
J. M. BRAND
Research22 Sept 1972
Nature

Volume: 239, P: 225-226
2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

R. Wilson
R. Ainscough
P. Wohldman
Research03 Mar 1994
Nature

Volume: 368, P: 32-38
Acclimatization Status of Temperate-zone Man

R. K. MACPHERSON
Research01 Nov 1958
Nature

Volume: 182, P: 1240-1241
RNA-responsive elements for eukaryotic translational control

The translation of transgenes is regulated using RNA sensors.

Evan M. Zhao
Angelo S. Mao
James J. Collins
Research28 Oct 2021
Nature Biotechnology

Volume: 40, P: 539-545
Cloning of a gene that is rearranged in patients with choroideraemia

Frans P. M. Cremers
Dorien J. R. van de Pol
Hans-Hilger Ropers
Research18 Oct 1990
Nature

Volume: 347, P: 674-677
Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients

The shift in fluorescence lifetime of tumour tissue with respect to normal tissue after systemic injection of the near-infrared dye indocyanine green can be used to distinguish tumour tissue from normal tissue with high accuracy.

Rahul Pal
Thinzar M. Lwin
Anand T. N. Kumar
Research16 Oct 2023
Nature Biomedical Engineering

Volume: 7, P: 1649-1666
Biogenic non-crystalline U^(IV) revealed as major component in uranium ore deposits

Crystalline uraninite is believed to be the dominant form in uranium deposits. Here, the authors find that non-crystalline U^(IV) generated through biologically mediated U^(VI) reduction is the predominant U^(IV)species in ore deposits, implying that biogenic processes are more important than previously thought.

Amrita Bhattacharyya
Kate M. Campbell
Thomas Borch
ResearchOpen Access01 Jun 2017
Nature Communications

Volume: 8, P: 1-8
Zellweger Syndrome Amniocytes: Morphological Appearance and a Simple Sedimentation Method for Prenatal Diagnosis

Paul B Lazarow
Gillian M Small
Joseph Dancis
Research01 Jul 1988
Pediatric Research

Volume: 24, P: 63-67
Paper Chromatography of Browning Reaction Fluorogens

A. R. PATTON
PATRICIA CHISM
Research10 Mar 1951
Nature

Volume: 167, P: 406
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

Kevin Barton
Natarajan Muthusamy
Jeffrey M. Leiden
Research04 Jan 1996
Nature

Volume: 379, P: 81-85
Rapid discovery and evolution of nanosensors containing fluorogenic amino acids

Binding-activated optical sensors are powerful tools, but their development can be slow and laborious. Here, authors introduce a platform to expedite biosensor discovery and evolution using genetically encodable fluorogenic amino acids.

Erkin Kuru
Jonathan Rittichier
George M. Church
ResearchOpen Access05 Sept 2024
Nature Communications

Volume: 15, P: 1-14
Localization of Friedreich ataxia phenotype with selective vitamin E deficiency to chromosome 8q by homozygosity mapping

C. Ben Hamida
N. Doerflinger
M. Kœnig
Research01 Oct 1993
Nature Genetics

Volume: 5, P: 195-200
Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA

Noriaki Shimizu
Teru Kanda
Geoffrey M. Wahl
Research01 Jan 1996
Nature Genetics

Volume: 12, P: 65-71
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health

LXRα is highly expressed in hepatocytes, where it regulates cholesterol abundance and stimulates lipogenesis. The authors provide evidence in humans and mice that impaired LXRα signalling is hepatotoxic, despite its potent lipogenic actions.

Sam M. Lockhart
Milan Muso
Stephen O’Rahilly
ResearchOpen Access25 Sept 2024
Nature Metabolism

Volume: 6, P: 1922-1938
Increased neurovirulence associated with a single nucleotide change in a noncoding region of the Sabin type 3 poliovaccine genome

D. M. A. Evans
G. Dunn
J. V. Maizel Jr
Research11 Apr 1985
Nature

Volume: 314, P: 548-550
Coral-snake pattern recognition and stimulus generalisation by naive great kiskadees (Aves: Tyrannidae)

SUSAN M. SMITH
Research10 Feb 1977
Nature

Volume: 265, P: 535-536
Observations of CP 1133 with a Fast Night Sky Cerenkov Detector

E. P. O'MONGAIN
N. A. PORTER
B. G. LAWLESS
Research28 Sept 1968
Nature

Volume: 219, P: 1348-1349
Oculotrema hippopotami (Trematoda: Monogenea) in Uganda

JUNE P. THURSTON
R. M. LAWS
Research13 Mar 1965
Nature

Volume: 205, P: 1127
Submucosal glands are the predominant site of CFTR expression in the human bronchus

John F. Engelhardt
James R. Yankaskas
James M. Wilson
Research01 Nov 1992
Nature Genetics

Volume: 2, P: 240-248
Metastability of Rotationally Hot Dihelium at 77° K

A. B. CALLEAR
R. E. M. HEDGES
Research16 Sept 1967
Nature

Volume: 215, P: 1267-1268
Murine muscular dystrophy caused by a mutation in the laminin α2 (Lama2) gene

Hong Xu
Xiao-Rong Wu
Eva Engvall
Research01 Nov 1994
Nature Genetics

Volume: 8, P: 297-302
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis

Trehalose metabolism has been linked to Mycobacterium tuberculosis (Mtb) virulence and biofilm formation. Here, using a model of drug-tolerant persisters and metabolomics, the authors dissect the role of trehalose metabolism in Mtb persister formation, linking trehalose-catalytic shift to antibiotic resistance.

Jae Jin Lee
Sun-Kyung Lee
Hyungjin Eoh
ResearchOpen Access02 Jul 2019
Nature Communications

Volume: 10, P: 1-12
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29

VARP is bound to endosomes and functions as a protein:protein interaction platform. Here, the authors present the NMR structure of the complex between the retromer subunit VPS29 and a VARP Zn-fingernail microdomain that is structurally distinct from Zn-fingers and further show that mutations, which abolish VPS29:VARP binding, inhibit trafficking from endosomes to the cell surface.

Harriet Crawley-Snowdon
Ji-Chun Yang
David J. Owen
ResearchOpen Access06 Oct 2020
Nature Communications

Volume: 11, P: 1-15
Bistable and photoswitchable states of matter

Polymers cross-linked with dynamic bonds can switch the phase from solid to fluid upon stimulus but return quickly to the solid state once the stimulus is removed. Here the authors report a light triggered permanent solid to fluid transition at room temperature with inherent spatiotemporal control in either direction

Brady T. Worrell
Matthew K. McBride
Christopher N. Bowman
ResearchOpen Access18 Jul 2018
Nature Communications

Volume: 9, P: 1-7
Respiratory mucosal immune memory to SARS-CoV-2 after infection and vaccination

Evidence from animal models suggest a vital role for mucosal vaccination in inducing protection from coronavirus infection. Here the authors examine the B and T cell responses at the lower airways, and contrast humoral and cellular immunity of people after infection and vaccination.

Elena Mitsi
Mariana O. Diniz
Daniela M. Ferreira
ResearchOpen Access26 Oct 2023
Nature Communications

Volume: 14, P: 1-14
Plant species’ origin predicts dominance and response to nutrient enrichment and herbivores in global grasslands

It remains unclear whether exotic and native species are functionally different. Using a global grassland experiment, Seabloomet al. show that native and exotic species respond differently to two globally pervasive environmental changes, addition of mineral nutrients and alteration of herbivore density.

Eric W. Seabloom
Elizabeth T. Borer
Louie Yang
ResearchOpen Access15 Jul 2015
Nature Communications

Volume: 6, P: 1-8
Global irrigation contribution to wheat and maize yield

There are big uncertainties in the contribution of irrigation to crop yields. Here, the authors use Bayesian model averaging to combine statistical and process-based models and quantify the contribution of irrigation for wheat and maize yields, finding that irrigation alone cannot close yield gaps for a large fraction of global rainfed agriculture.

Xuhui Wang
Christoph Müller
Shilong Piao
ResearchOpen Access23 Feb 2021
Nature Communications

Volume: 12, P: 1-8
Translational activation of the lck proto-oncogene

Jamey D. Marth
Robert W. Overell
Roger M. Perlmutter
Research10 Mar 1988
Nature

Volume: 332, P: 171-173
Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer

Mutation profiling of pediatric cancers can help determine treatment options, however, large-scale datasets are rare. Here, the authors describe an institutional application of targeted sequencing to pediatric solid tumours, and identify potential therapeutic implications for identified mutations.

Suzanne J. Forrest
Hersh Gupta
Katherine A. Janeway
ResearchOpen Access11 Jul 2024
Nature Communications

Volume: 15, P: 1-11

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