Nature Search

Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate

L P Setälä
M I Tammi
V-M Kosma
ResearchOpen Access12 Feb 1999
British Journal of Cancer

Volume: 79, P: 1133-1138
FinnGen provides genetic insights from a well-phenotyped isolated population

Genome-wide association studies of individuals from an isolated population (data from the Finnish biobank study FinnGen) and consequent meta-analyses facilitate the identification of previously unknown coding variant associations for both rare and common diseases.

Mitja I. Kurki
Juha Karjalainen
Aarno Palotie
ResearchOpen Access18 Jan 2023
Nature

Volume: 613, P: 508-518
Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations

Lamin A/C gene mutations cause dilated cardiomyopathy associated with cofilin-1 phosphorylation and actin destabilization. Here, the authors show that phosphorylated cofilin-1 blunts the MRTF-A/SRF axis, leading to decreased tubulin acetylation and altered cardiac structure and function.

Caroline Le Dour
Maria Chatzifrangkeskou
Antoine Muchir
ResearchOpen Access22 Dec 2022
Nature Communications

Volume: 13, P: 1-21
Soil nematode abundance and functional group composition at a global scale

High-resolution spatial maps of the global abundance of soil nematodes and the composition of functional groups show that soil nematodes are found in higher abundances in sub-Arctic regions, than in temperate or tropical regions.

Johan van den Hoogen
Stefan Geisen
Thomas Ward Crowther
Research24 Jul 2019
Nature

Volume: 572, P: 194-198
Land use alters the resistance and resilience of soil food webs to drought

A study shows that soil food webs directly help mitigate the effects of drought on soil nutrients. The fungal-based food webs of grassland were more resistant to bouts of drought than the bacterial-based food webs of intensively managed wheat, and retained more carbon and nitrogen in the soil.

Franciska T. de Vries
Mira E. Liiri
Richard D. Bardgett
Research29 Jan 2012
Nature Climate Change

Volume: 2, P: 276-280
Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Narcolepsy has genetic and environmental risk factors, but the specific genetic risk loci and interaction with environmental triggers are not well understood. Here, the authors identify genetic loci for narcolepsy, suggesting infection as a trigger and dendritic and helper T cell involvement.

Hanna M. Ollila
Eilon Sharon
Emmanuel J. Mignot
ResearchOpen Access15 May 2023
Nature Communications

Volume: 14, P: 1-13
Light painting photography makes particulate matter air pollution visible

A long-exposure photography technique combined with air pollution monitoring can be used to create light paintings to highlight air pollution and create a broader public discourse on how to improve it, suggests the environmental community project “Air of the Anthropocene”.

Francis D. Pope
Robin Price
Faye Wilder
ResearchOpen Access05 Jun 2024
Communications Earth & Environment

Volume: 5, P: 1-8
Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata

Many genetic factors that contribute to uterine leiomyomata (UL) - the most common tumours of the female genital tract - remain to be discovered. Here, the authors conduct a UL meta-genome-wide association study, and find loci related to altered muscle tissue biology that are associated with UL.

Eeva Sliz
Jaakko S. Tyrmi
Johannes Kettunen
ResearchOpen Access01 Feb 2023
Nature Communications

Volume: 14, P: 1-14
Expression of thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection

J-H Choi
H-Y Lim
K B Kim
ResearchOpen Access16 Jan 2001
British Journal of Cancer

Volume: 84, P: 186-192
Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population

Mitja I. Kurki
Juha Karjalainen
Aarno Palotie
Amendments and CorrectionsOpen Access24 Feb 2023
Nature

Volume: 615, P: E19
Prognostic factors in gastric cancer: the value of vascular invasion, mitotic rate and lymphoplasmacytic infiltration

LP Setälä
V-M Kosma
EM Alhava
Research01 Sept 1996
British Journal of Cancer

Volume: 74, P: 766-772
Narcolepsy as a potential risk factor for Schizophrenia

Reyhane Eghtedarian
Anniina M. Tervi
Hanna M. Ollila
ResearchOpen Access17 Feb 2025
Translational Psychiatry

Volume: 15, P: 1-10
Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis

A Schmaus
S Klusmeier
J P Sleeman
ResearchOpen Access17 Jun 2014
British Journal of Cancer

Volume: 111, P: 559-567
Novel loci and biomedical consequences of iron homoeostasis variation

The largest meta-analysis of GWASs of hepcidin and sTfR identified 43 genomic loci, of which 15 new. Mendelian randomisation revealed associations of systemic iron status and iron-related loci with selected health outcomes across multiple domains.

Elias Allara
Steven Bell
Emanuele Di Angelantonio
ResearchOpen Access06 Dec 2024
Communications Biology

Volume: 7, P: 1-17
Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

K Huhtinen
P Suvitie
A Perheentupa
ResearchOpen Access31 Mar 2009
British Journal of Cancer

Volume: 100, P: 1315-1319
NTHL1 is a recessive cancer susceptibility gene

Anna K. Nurmi
Liisa M. Pelttari
Heli Nevanlinna
ResearchOpen Access30 Nov 2023
Scientific Reports

Volume: 13, P: 1-14
A methanolic extract of Zanthoxylum bungeanum modulates secondary metabolism regulator genes in Aspergillus flavus and shuts down aflatoxin production

Asmaa Abbas
Colin W. Wright
Anssi M. Malinen
ResearchOpen Access09 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
A global database of soil nematode abundance and functional group composition

Johan van den Hoogen
Stefan Geisen
Thomas W. Crowther
ResearchOpen Access26 Mar 2020
Scientific Data

Volume: 7, P: 1-8
Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis

E Broberg
N Setälä
V Hukkanen
Research22 Jun 2001
Gene Therapy

Volume: 8, P: 769-777

Search

Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate

FinnGen provides genetic insights from a well-phenotyped isolated population

Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations

Soil nematode abundance and functional group composition at a global scale

Land use alters the resistance and resilience of soil food webs to drought

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Light painting photography makes particulate matter air pollution visible

Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata

Expression of thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population

Prognostic factors in gastric cancer: the value of vascular invasion, mitotic rate and lymphoplasmacytic infiltration

Narcolepsy as a potential risk factor for Schizophrenia

Accumulation of small hyaluronan oligosaccharides in tumour interstitial fluid correlates with lymphatic invasion and lymph node metastasis

Novel loci and biomedical consequences of iron homoeostasis variation

Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

NTHL1 is a recessive cancer susceptibility gene

A methanolic extract of Zanthoxylum bungeanum modulates secondary metabolism regulator genes in Aspergillus flavus and shuts down aflatoxin production

A global database of soil nematode abundance and functional group composition

Expression of interleukin-4 but not of interleukin-10 from a replicative herpes simplex virus type 1 viral vector precludes experimental allergic encephalomyelitis

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