It is unclear whether viral particles can induce membrane curvature. Binding of Simian virus 40 (SV40) to the GM1 ganglioside on host plasma membranes leads to membrane curvature and the formation of invaginations in cells and in giant unilamellar vesicles, an effect required for viral infection.
- Helge Ewers
- Winfried Römer
- Ludger Johannes