Nature Search

Incorporation of DL-[2-¹⁴ C] Mevalonic Acid Lactone into Polyisoprene

R. G. O. KEKWICK
B. L. ARCHER
C. G. MOORE
Research25 Jul 1959
Nature

Volume: 184, P: 268-270
A Radio Source with a Very Unusual Spectrum

J. G. BOLTON
F. F. GARDNER
M. B. MACKEY
Research17 Aug 1963
Nature

Volume: 199, P: 682-683
Nitrosation of phenols in smoked bacon

M. E. KNOWLES
J. GILBERT
D. J. MCWEENY
Research14 Jun 1974
Nature

Volume: 249, P: 672-673
Direct observation of twisted stacking domains in the van der Waals magnet CrI₃

Artificial stacking of van der Waals materials is an effective method to design and investigate emergent physical properties in condensed matter systems. Here, the authors characterize the natural twisted layer structure of CrI₃, showing its dependence on the sample fabrication process and its implications for the magnetic properties of the material.

Myeongjin Jang
Sol Lee
Kwanpyo Kim
ResearchOpen Access15 Jul 2024
Nature Communications

Volume: 15, P: 1-9
The evolution of lung cancer and impact of subclonal selection in TRACERx

Analyses of multiregional tumour samples from 421 patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome.

Alexander M. Frankell
Michelle Dietzen
Charles Swanton
ResearchOpen Access12 Apr 2023
Nature

Volume: 616, P: 525-533
Direct observations of a surface eigenmode of the dayside magnetopause

Surface waves on the boundary between a magnetosphere and the surrounding plasma might get trapped by the ionosphere forming an eigenmode. Here, Archer et al. show direct observations of this proposed mechanism at Earth’s magnetosphere by analyzing the response to an isolated fast plasma jet detected by the THEMIS satellites.

M. O. Archer
H. Hietala
V. Angelopoulos
ResearchOpen Access12 Feb 2019
Nature Communications

Volume: 10, P: 1-11
Accumulation of Antibody-forming Cells in Spleens of Pre-immunized Irradiated Mice after Transplantation of Syngeneic Bone Marrow

YU. M. ZARETSKAYA
E. I. PANTELEEV
R. V. PETROV
Research08 Feb 1969
Nature

Volume: 221, P: 567-568
Germline variant affecting p53β isoforms predisposes to familial cancer

Pathogenic germline variants in TP53 predispose to a variety of cancers, but variants solely affecting alternatively spliced isoforms of TP53 are understudied. Here, the authors identify a heterozygous stop-lost variant that specifically affects p53β isoforms and predisposes to familial cancer using germline whole-exome sequencing and functional genomics assays.

Stephanie A. Schubert
Dina Ruano
Tom van Wezel
ResearchOpen Access18 Sept 2024
Nature Communications

Volume: 15, P: 1-15
Powerful New Inhibitor of Murine Leukaemia and Sarcoma Viruses

J. C. CHERMANN
M. RAYNAUD
G. MATHÉ
Research11 Jul 1970
Nature

Volume: 227, P: 173-174
Emergent order in the kagome Ising magnet Dy₃Mg₂Sb₃O₁₄

Frustration in lattices of interacting spins can lead to rich and exotic physics, such as fractionalized excitations and emergent order. Here, the authors demonstrate a low-temperature transition from a disordered spin-ice-like phase to an emergent charge ordered phase in the bulk kagome Ising magnet Dy₃Mg₂Sb₃O₁₄.

Joseph A. M. Paddison
Harapan S. Ong
S. E. Dutton
ResearchOpen Access20 Dec 2016
Nature Communications

Volume: 7, P: 1-8
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Substantial oxygen loss and chemical expansion in lithium-rich layered oxides at moderate delithiation

Li-rich oxides were found to slowly release considerable quantities of oxygen at varying states of charge. These observations point to the intrinsic instability of oxygen in partially charged oxides and highlight the need for degradation studies.

Peter M. Csernica
Kit McColl
William C. Chueh
Research17 Oct 2024
Nature Materials

Volume: 24, P: 92-100
Pronethalol-induced Reversal of Adrenergic Vasodepression

M. GONÇALVES MOREIRA
W. OSSWALD
Research04 Dec 1965
Nature

Volume: 208, P: 1006-1007
Synthesis of N-Phosphoryl-D- and L-Lombricine

IVA M. BEATTY
A. H. ENNOR
D. I. MAGRATH
Research17 Dec 1960
Nature

Volume: 188, P: 1026-1027
Body composition and lung cancer-associated cachexia in TRACERx

Results of the TRACERx study shed new light into the association between body composition and body weight with survival in individuals with non-small cell lung cancer, and delineate potential biological processes and mediators contributing to the development of cancer-associated cachexia.

Othman Al-Sawaf
Jakob Weiss
Charles Swanton
Research12 Apr 2023
Nature Medicine

Volume: 29, P: 846-858
Large sulfur isotope fractionations in Martian sediments at Gale crater

Ancient Mars may have had an active sulfur cycle. In situ analyses by the Curiosity rover reveal large variations in the current sulfur isotopic composition of Martian sediments that can be explained by geologic and atmospheric processes.

H. B. Franz
A. C. McAdam
B. Sutter
Research07 Aug 2017
Nature Geoscience

Volume: 10, P: 658-662
Annual Cycle in the Size of the Gut of the Purple Sea Urchin, Strongylocentrotus purpuratus (Stimpson)

JOHN M. LAWRENCE
ADDISON L. LAWRENCE
NICHOLAS D. HOLLAND
Research01 Mar 1965
Nature

Volume: 205, P: 1238-1239
Disputed African origin of human populations

PIERRE DARLU
PASCAL TASSY
Research10 Sept 1987
Nature

Volume: 329, P: 111
Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance

Red blood cells (RBCs) are phagocytosed in the spleen in sickle cell disease and malaria. Here, Cao et al. show that high mannose N-glycans, exposed on diseased or oxidized RBC surfaces, bind mannose receptor CD206 on host cells, mediating phagocytosis.

Huan Cao
Aristotelis Antonopoulos
Mark A. Vickers
ResearchOpen Access19 Mar 2021
Nature Communications

Volume: 12, P: 1-13
Quantifying the ozone and ultraviolet benefits already achieved by the Montreal Protocol

Ozone-depleting substances have been controlled by the 1987 Montreal Protocol, ensuring atmospheric concentrations are now in decline. Here, the authors use a 3D model and suggest that these controls have already had significant benefits, with much larger ozone depletion than previously thought avoided by the protocol.

M. P. Chipperfield
S. S. Dhomse
J. A. Pyle
ResearchOpen Access26 May 2015
Nature Communications

Volume: 6, P: 1-8
Dynamic signatures of spin-lattice coupling in the layered ferrimagnet Mn₃Si₂Te₆

Luis M. Martinez
Yu Liu
Prashant Padmanabhan
ResearchOpen Access04 Sept 2025
npj Spintronics

Volume: 3, P: 1-7
MSH2 deficient mice are viable and susceptible to lymphoid tumours

A.H. Reitmair
R. Schmits
T. W. Mak
Research01 Sept 1995
Nature Genetics

Volume: 11, P: 64-70
Ethylene in soil

J. M. LYNCH
Research14 Aug 1975
Nature

Volume: 256, P: 576-577
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA₁₆₅-dependent neovascularization

Proteoglycans are glycosylated proteins that play a number of structural and signalling functions. Here, Corti, Wang et al. show that the N-terminal sequence of proteoglycan Syndecan-2 selectively increases 6-O sulfation of its heparan sulfate chains, and that this promotes formation of a ternary Sdc2/VEGFA/VEGFR2 complex leading to increased angiogenesis.

Federico Corti
Yingdi Wang
Michael Simons
ResearchOpen Access05 Apr 2019
Nature Communications

Volume: 10, P: 1-14
A model for the evolution of the Grampian tract in the early Caledonides and Appalachians

John F. Dewey
Robert M. Shackleton
Research08 Nov 1984
Nature

Volume: 312, P: 115-121
Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing

Dissecting the adaptive exercise response of the neurogenic stem-cell niche in the dentate gyrus by single-nucleus RNA sequencing reveals the molecular mediators that underlie exercise’s protective effects in Alzheimer’s disease.

Joana F. da Rocha
Michelle L. Lance
Christiane D. Wrann
Research12 Jun 2025
Nature Neuroscience

Volume: 28, P: 1546-1561
Quantal calcium release by purified reconstituted inositol 1,4,5-trisphosphate receptors

Christopher D. Ferris
Andrew M. Cameron
Solomon H. Snyder
Research26 Mar 1992
Nature

Volume: 356, P: 350-352
Protean Displays as Inducers of Conflict

PETER M. DRIVER
DAVID A. HUMPHRIES
Research06 Jun 1970
Nature

Volume: 226, P: 968-969
Generation length and rates of hominoid molecular evolution (reply)

E. J. TODARO
R. BENVENIFTE
Research01 Sept 1977
Nature

Volume: 269, P: 354-355
A New Reticuloendothelial System Stimulating Agent (‘Restim’) from Shark Livers

JOHN H. HELLER
VARSENIG Z. PASTERNAK
M. S. HELLER
Research31 Aug 1963
Nature

Volume: 199, P: 904-905
Enzymatic Etching of Single Crystals of Naphthalene

J. M. THOMAS
J. O. WILLIAMS
E. GRIFFITHS
Research09 Jul 1966
Nature

Volume: 211, P: 181-182
Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation

Nicole M. Mahoney
Paul A. Janmey
Steven C. Almo
Research01 Nov 1997
Nature Structural Biology

Volume: 4, P: 953-960
Interaction of multiplication-stimulating activity with chick embryo fibroblasts demonstrates a growth receptor

MATTHEW M. RECHLER
JUDY M. PODSKALNY
S. PETER NISSLEY
Research15 Jan 1976
Nature

Volume: 259, P: 134-136
Divergent transcriptional regulation of astrocyte reactivity across disorders

Transcriptional changes associated with astrocyte reactivity are highly heterogeneous and are customized from vast numbers of potential DEGs through context-specific combinatorial interactions amongst transcriptional regulators.

Joshua E. Burda
Timothy M. O’Shea
Michael V. Sofroniew
Research25 May 2022
Nature

Volume: 606, P: 557-564
Temperature Dependence of Contact Angles

M. C. PHILLIPS
A. C. RIDDIFORD
Research01 Mar 1965
Nature

Volume: 205, P: 1005-1006
The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

Revumenib, a potent and selective oral inhibitor of the menin–KMT2A interaction, is associated with a low frequency of treatment-related adverse events and promising clinical activity in patients with relapsed or refractory acute leukaemia.

Ghayas C. Issa
Ibrahim Aldoss
Eytan M. Stein
ResearchOpen Access15 Mar 2023
Nature

Volume: 615, P: 920-924
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Intracellular calcium ions decrease the affinity of the GABA receptor

M. Inoue
Y. Oomura
N. Akaike
Research13 Nov 1986
Nature

Volume: 324, P: 156-158
Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma

The molecular mechanisms underlying MYC overexpression in group 3 medulloblastoma remain to be explored. Here, the authors highlight the involvement of the mitochondrial pyruvate carrier- SOD2 signalling pathway in the regulation of MYC protein abundance.

Emma Martell
Helgi Kuzmychova
Tanveer Sharif
ResearchOpen Access02 May 2023
Nature Communications

Volume: 14, P: 1-26
Origin of anti-parallelism in β-keratin

M. FEUGHELMAN
Research27 Mar 1986
Nature

Volume: 320, P: 314
Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

MSK-IMPACT is a clinical sequencing platform able to detect genomic mutations, copy number alterations and structural variants in a panel of cancer-related genes. This assay is implemented prospectively to inform patient enrollment in genomically matched clinical trials at Memorial Sloan Kettering Cancer Center (MSKCC). Sequencing results of tumor and matched normal tissue from a cohort of >10,000 patients with detailed clinical annotation provide an overview of the genomic landscape of advanced solid cancers and bring new insights into molecularly guided cancer therapy.

Ahmet Zehir
Ryma Benayed
Michael F Berger
Research08 May 2017
Nature Medicine

Volume: 23, P: 703-713
Hybrid schwannoma–perineurioma frequently harbors VGLL3 rearrangement

Brendan C. Dickson
Cristina R. Antonescu
Jason L. Hornick
Research01 Mar 2021
Modern Pathology

Volume: 34, P: 1116-1124
Radio Observations of Jupiter during 1962

J. A. GLEDHILL
G. M. GRUBER
M. C. BOSCH
Research02 Feb 1963
Nature

Volume: 197, P: 474-475
Compressibility and Specific Evaporation Resistance of the Monolayers of Long-Chain Alcohols and Glycol Monoalkyl Ethers

A. V. DEO
S. B. KULKARNI
A. B. BISWAS
Research22 Jul 1961
Nature

Volume: 191, P: 378-379
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Circular extrachromosomal DNA in high-risk medulloblastoma contributes to tumor heterogeneity and associates with relapse and survival. Enhancer rewiring events involving known oncogenes are frequent events, affecting transcription and proliferation.

Owen S. Chapman
Jens Luebeck
Lukas Chavez
ResearchOpen Access09 Nov 2023
Nature Genetics

Volume: 55, P: 2189-2199
Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

Monika König
Anne M. Zimmer
Andreas Zimmer
Research10 Oct 1996
Nature

Volume: 383, P: 535-538
Thermosensitive hydrogel releasing nitric oxide donor and anti-CTLA-4 micelles for anti-tumor immunotherapy

Nitric oxide exerts a multitude of physiological functions and has also been exploited for anticancer therapies. Here the authors report the design of a micelle-releasing thermosensitive hydrogel system for the concomitant locoregional and lymphatic delivery of a nitric oxide donor and an anti-CTLA4 antibody, showing anti-tumor immune responses in preclinical cancer models.

Jihoon Kim
David M. Francis
Susan N. Thomas
ResearchOpen Access18 Mar 2022
Nature Communications

Volume: 13, P: 1-13
Cloning and expression of a rat D₂ dopamine receptor cDNA

James R. Bunzow
Hubert H. M. Van Tol
Olivier Civelli
Research29 Dec 1988
Nature

Volume: 336, P: 783-787
Nutritionally Small-for-Dates Rats: Their Subsequent Growth, Regional Brain 5-Hydroxytryptamine Turnover, and Behavior

J L Smart
M D Tricklebank
John Dobbing
Research01 Sept 1976
Pediatric Research

Volume: 10, P: 807-811
Tissue Eosinophilia in Hypersensitivity Reactions as revealed by the Human Skin Window

D. EIDINGER
M. RAFF
B. ROSE
Research17 Nov 1962
Nature

Volume: 196, P: 683-684

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