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Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health

Lecoutre, Maqdasy and Rizo-Roca show that whole-body pharmacological inhibition or adipocyte-specific deletion of glutaminase in mice activates thermogenesis in inguinal adipocytes and promotes metabolic health. They also link decreased plasma and adipose tissue glutamine-to-glutamate ratios to insulin resistance in humans with obesity.

Simon Lecoutre
Salwan Maqdasy
Mikael Rydén
ResearchOpen Access15 Jul 2024
Nature Metabolism

Volume: 6, P: 1329-1346
Relation between male breast cancer and prostate cancer

L H Sobin
M Sherif
Research01 Nov 1980
British Journal of Cancer

Volume: 42, P: 787-790
Skin immunisation activates an innate lymphoid cell-monocyte axis regulating CD8⁺ effector recruitment to mucosal tissues

Mucosal immunisation is important for initiating mucosal CD8⁺ Tcell responses but mucosal recruitment of protective CD8⁺ T cells can also be induced by skin immunisation. Here the authors examine the underlying mechanism and report a novel role for ILC1 recruiting CD8⁺ T cells to the mucosa after skin immunisation.

Marija Zaric
Pablo D. Becker
Linda S. Klavinskis
ResearchOpen Access17 May 2019
Nature Communications

Volume: 10, P: 1-14
First record of a living coelacanth from North Maluku, Indonesia

Alexis Chappuis
I Gede Hendrawan
Gino V. Limmon
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-5
Dynamically tuning friction at the graphene interface using the field effect

Electric fields achieved by applying electrical bias directly between the sliding surfaces are commonly used to tune friction. Here, the authors reveal that friction between graphene and a semiconductor is sensitive to the charge density of graphene while influenced by an indirect electric field.

Gus Greenwood
Jin Myung Kim
Rosa M. Espinosa-Marzal
ResearchOpen Access19 Sept 2023
Nature Communications

Volume: 14, P: 1-12
Bacterial transcriptomics: what is beyond the RNA horiz-ome?

Technological advances have revealed many new aspects of bacterial transcription. In this Review, Serrano and colleagues describe the changes in our understanding of bacterial transcription and how this has revealed complexity of regulation that is similar to that observed in eukaryotes.

Marc Güell
Eva Yus
Luis Serrano
Reviews12 Aug 2011
Nature Reviews Microbiology

Volume: 9, P: 658-669
Direct observation and quantitative characterization of chemotactic behaviors in Caribbean coral larvae exposed to organic and inorganic settlement cues

Koumudhi Deshpande
Daniel Gysbers
Gabriel Juarez
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-17
Evaluation of the genotoxic and transformation potential induced by asbestos compared to cleavage fragments

Sebastiano La Maestra
Gaia M. Militello
Laura Gaggero
ResearchOpen Access29 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Alpha band disruption in the AD-continuum starts in the Subjective Cognitive Decline stage: a MEG study

D. López-Sanz
R. Bruña
F. Maestú
ResearchOpen Access24 Nov 2016
Scientific Reports

Volume: 6, P: 1-11
Predicting effects of structural stress in a genome-reduced model bacterial metabolism

Oriol Güell
Francesc Sagués
M. Ángeles Serrano
ResearchOpen Access29 Aug 2012
Scientific Reports

Volume: 2, P: 1-8

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