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Cell Death and Differentiation (1)
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Showing 1–4 of 4 results

Advanced filters: Author: Maria I. Bergamasco Clear advanced filters

KAT6B overexpression rescues embryonic lethality in homozygous null KAT6A mice restoring vitality and normal lifespan

KAT6A and KAT6A are epigenetic regulators with critical functions in embryonic development. Mutations in either KAT6A or KAT6B result in distinct congenital disorders in human patients. Surprisingly, overexpression of KAT6B can rescue loss of KAT6A.

Maria. I. Bergamasco
Yuqing Yang
Tim Thomas
ResearchOpen Access25 Feb 2025
Nature Communications

Volume: 16, P: 1-16
Metabolomic profiling in heart failure as a new tool for diagnosis and phenotyping

Maria V. Kozhevnikova
Yuri N. Belenkov
Svetlana A. Appolonova
ResearchOpen Access07 Apr 2025
Scientific Reports

Volume: 15, P: 1-15
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Selective inhibitors of KAT6A and KAT6B inhibit MYST-catalysed histone acetylation, induce cell cycle exit and cellular senescence without causing DNA damage, and arrest lymphoma progression in mouse models.

Jonathan B. Baell
David J. Leaver
Tim Thomas
Research01 Aug 2018
Nature

Volume: 560, P: 253-257
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death

Farrah El-Saafin
Maria I. Bergamasco
Anne K. Voss
Research31 Mar 2022
Cell Death & Differentiation

Volume: 29, P: 1013-1027