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We report both spin- and orbital-sourced Berry curvature in LaAlO₃/SrTiO₃ interfaces grown along the [111] direction.

From 2014–2017, marine heatwaves caused global mass coral bleaching, where the corals lose their symbiotic algae. The authors find, this event exceeded the severity of all prior global bleaching events in recorded history, with approximately half the world’s reefs bleaching and 15% experiencing substantial mortality.

Spin–orbit coupling gives rise to a plethora of rich phenomena in many condensed matter and atomic systems. Syzranov et al.study the role of dipole–dipole interactions in ultracold polar molecule gases and show that they produce an effective spin–orbit coupling that generates chiral excitations.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

The dispersionless nature of Aharonov-Bohm effect is still debated. Here, the authors show an asymmetry in the diffraction pattern of an electron beam induced and controlled by an inaccessible magnetic flux, which means electrons behave “as if” an Aharonov-Bohm “force” was present.

Here the authors show that persistent antigen stimulation drives the generation of CD8⁺ tissue-resident exhausted T cells with distinct developmental origins, function and therapeutic responsiveness when compared to CD8⁺ tissue-resident memory T cells.

Static maps are key tools for assessing ecosystem services. This study shows that hotspots of three boreal-forest services—wood production, bilberry production and topsoil carbon storage—can vary widely over just ten years, suggesting the value of dynamic tools to manage dynamic landscapes.

Topological rainbow trapping combines slow-wave effects with topological robustness to spatially separate wave frequencies. This Review highlights its physical principles, implementation in different waves-based systems and potential technological impacts.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

Tree diversity is thought to benefit forest ecosystems, but evidence from large-scale studies is scarce. This study of a 400,000 km²forest area shows that higher tree species richness supports higher levels of multiple ecosystem services, and therefore also a more sustainable management of production forests.

As presented at the American Heart Association Conference 2025, patients with chest pain and without obstructive coronary artery disease benefit from treatment informed by cardiovascular magnetic resonance.

Inventory data from more than 1 million trees across African, Amazonian and Southeast Asian tropical forests suggests that, despite their high diversity, just 1,053 species, representing a consistent ~2.2% of tropical tree species in each region, constitute half of Earth’s 800 billion tropical trees.

Systems with Weyl excitations can display very interesting physical phenomena. Here the authors demonstrate that Weyl excitations exist generically in 3D systems of dipolar particles following angular momentum transfer, and discuss how to observe them in cold alkaline-earth-atom systems.

The authors find that TDP-43 loss of function—the pathology defining the neurodegenerative conditions ALS and FTD—induces novel mRNA polyadenylation events, which have different effects, including an increase in RNA stability, leading to higher protein levels.

Two dimensional (2D) material with intriguing physical properties promises advanced electronic and spintronic technologies. Here the authors predict a magnetic photo-galvanic effect (MPGE) in bilayer 2D CrI₃ due to the magnetism-induced asymmetry of the carrier velocity in the band-structure topology.

Here the authors define an inter-protomeric mechanism of deglycosylation of human IgG antibodies for corynebacterial IgG-specific ENGases and demonstrate that in vivo CU43 treatment preserve the neutralizing capacity of anti-influenza IgG antibodies.

Empirically based models of disease progression in familial frontotemporal dementia reveal the relative ordering of clinical, neuroimaging, and fluid biomarker changes and facilitate novel clinical trial designs

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

High-harmonic generation has so far been driven only by classical light. Now, its driving by a bright squeezed vacuum—a quantum state of light—has been observed and shown to be more efficient than using classical light.

Phylogenomic analysis of 7,923 angiosperm species using a standardized set of 353 nuclear genes produced an angiosperm tree of life dated with 200 fossil calibrations, providing key insights into evolutionary relationships and diversification.

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Plant shoots and roots act in concert to ensure access to soil nutrients by adapting root growth. The manuscript identifies a key shoot signal, a mobile micro RNA, that systemically controls lateral root initiation to optimize nitrate supply.

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

A national prospective study of patients requiring hospitalization for COVID-19 demonstrates global cognitive deficits at 1 year, associated with elevated brain injury markers and reduced gray matter volume.

The antisense oligonucleotide rugonersen has acceptable safety and tolerability in children with Angelman syndrome and shows partial normalization of electroencephalogram abnormalities and clinical improvements relative to natural history.

Toxoplasma is a major infectious human parasite lethal to immunodeficient patients. This study identifies an apicoplast lipid transporter essential for parasite survival, which diverges from known chloroplast transporters.

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Chronic infection with SARS-CoV-2 leads to the emergence of viral variants that show reduced susceptibility to neutralizing antibodies in an immunosuppressed individual treated with convalescent plasma.

Here, the authors present and characterise a collection of human gut bacteria including novel taxa associated with health conditions and a large diversity of plasmids. All isolates, their genomes and metadata are publicly available, facilitating research by others (www.hibc.rwth-aachen.de).

Sera from vaccinated individuals and some monoclonal antibodies show a modest reduction in neutralizing activity against the B.1.1.7 variant of SARS-CoV-2; but the E484K substitution leads to a considerable loss of neutralizing activity.

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s  = 13 TeV and an integrated luminosity of 140 fb⁻¹.

Functional trait data could guide predictions of species responses to environmental change. Here, the authors show that winner and loser shrub species in the warming tundra biome overlap in trait space and may therefore be difficult to predict based on commonly measured traits.

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

A study of the evolution of the SARS-CoV-2 virus in England between September 2020 and June 2021 finds that interventions capable of containing previous variants were insufficient to stop the more transmissible Alpha and Delta variants.

Sequencing of haploid sugarcane, Saccharum spontaneum, allows assembly of a prototypical version of the sugarcane chromosome set. This new reference genome will serve as a resource to accelerate sugarcane improvement.

Using the valley degree of freedom in analogy to spin to encode qubits could be advantageous as many of the known decoherence mechanisms do not apply. Now long relaxation times are demonstrated for valley qubits in bilayer graphene quantum dots.

The Omicron variant evades vaccine-induced neutralization but also fails to form syncytia, shows reduced replication in human lung cells and preferentially uses a TMPRSS2-independent cell entry pathway, which may contribute to enhanced replication in cells of the upper airway. Altered fusion and cell entry characteristics are linked to distinct regions of the Omicron spike protein.

The detection of topological invariants in the bulk remains challenging even in state-of-the-art experiments. Here, Cardanoet al. propose a method to read-out the Zak phases and topological invariants in one-dimensional chiral systems and detect those in a photonic quantum walk of twisted photons.