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Showing 51–65 of 65 results

Advanced filters: Author: Martin Corcoran Clear advanced filters

Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

The crystal structure of CCR2 chemokine receptor in a complex with two different antagonists—one orthosteric the other allosteric—which functionally cooperate to inhibit CCR2.

Yi Zheng
Ling Qin
Tracy M. Handel
Research07 Dec 2016
Nature

Volume: 540, P: 458-461
The Dorsal Subiculum Mediates the Acquisition of Conditioned Reinstatement of Cocaine-Seeking

Rémi Martin-Fardon
Roberto Ciccocioppo
Friedbert Weiss
Research24 Oct 2007
Neuropsychopharmacology

Volume: 33, P: 1827-1834
Identification of the Niemann-Pick C1–like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor

The Niemann-Pick C1–like 1 cholesterol uptake receptor is an entry factor for the hepatitis C virus, according to this report. Ezetimibe, a drug that targets this receptor and is approved for use in humans, inhibits infection by the hepatitis C virus in a mouse model, highlighting the therapeutic potential of this discovery.

Bruno Sainz Jr
Naina Barretto
Susan L Uprichard
Research08 Jan 2012
Nature Medicine

Volume: 18, P: 281-285
p53 mutation with frequent novel codons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

Tim Crook
Louise A Brooks
Barry A Gusterson
Research01 Oct 1998
Oncogene

Volume: 17, P: 1681-1689
Identification and functional characterization of the first molluscan neuromedin U receptor in the slug, Deroceras reticulatum

Seung-Joon Ahn
Rory J. Mc Donnell
Man-Yeon Choi
ResearchOpen Access18 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
Endogenous insensitivity to the Orco agonist VUAA1 reveals novel olfactory receptor complex properties in the specialist fly Mayetiola destructor

Jacob A. Corcoran
Yonathan Sonntag
Christer Löfstedt
ResearchOpen Access22 Feb 2018
Scientific Reports

Volume: 8, P: 1-13
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils

Cesar Tovar
Ruth J. Pye
Gregory M. Woods
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-14
HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

Kaifan Dai
Salar N Khan
Richard T Wyatt
ResearchOpen Access16 Feb 2016
Scientific Reports

Volume: 6, P: 1-13
An extended motif in the SARS-CoV-2 spike modulates binding and release of host coatomer in retrograde trafficking

The cytosolic tail of β-coronavirus spike proteins contains dibasic motifs that must be able to bind to the host’s coatomer protein-I (COPI) for trafficking and be released for viral assembly in the ER-Golgi intermediate compartment. The critical residues in both the spike cytosolic tail and COPI are identified that modulate the association-dissociation kinetics.

Debajit Dey
Suruchi Singh
S. Saif Hasan
ResearchOpen Access08 Feb 2022
Communications Biology

Volume: 5, P: 1-13
Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI

M Beloueche-Babari
Y Jamin
S P Robinson
ResearchOpen Access13 Aug 2013
British Journal of Cancer

Volume: 109, P: 1562-1569
Cognitive Characterization of Schizophrenia Risk Variants Involved in Synaptic Transmission: Evidence of CACNA1C's Role in Working Memory

Donna Cosgrove
Omar Mothersill
Gary Donohoe
Research13 Jun 2017
Neuropsychopharmacology

Volume: 42, P: 2612-2622
Transcriptome analysis of a wild bird reveals physiological responses to the urban environment

Hannah Watson
Elin Videvall
Caroline Isaksson
ResearchOpen Access14 Mar 2017
Scientific Reports

Volume: 7, P: 1-10
Neurodevelopment, GABA System Dysfunction, and Schizophrenia

Martin J Schmidt
Karoly Mirnics
Reviews24 Apr 2014
Neuropsychopharmacology

Volume: 40, P: 190-206
Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations

Andrew M. Collins
Ayelet Peres
Mats Ohlin
CorrespondenceOpen Access19 Oct 2021
Genes & Immunity

Volume: 22, P: 335-338
Assessment and diagnosis of chronic dyspnoea: a literature review

Anthony Paulo Sunjaya
Nusrat Homaira
Christine Jenkins
ReviewsOpen Access08 Mar 2022
npj Primary Care Respiratory Medicine

Volume: 32, P: 1-8

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