Nature Search

Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation

Maturation of innate immune cells is a graded stereotypic process which is often conserved across species. Here authors label distinct neutrophil leukocyte developmental stages via generating combinations of transgenic zebrafish reporter strains, followed by transcriptome analysis of different neutrophil maturation stages and comparison to the gene expression profile of developing neutrophils from humans and mice.

Stefanie Kirchberger
Mohamed R. Shoeb
Martin Distel
ResearchOpen Access27 Feb 2024
Nature Communications

Volume: 15, P: 1-18
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

DNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic variation across vertebrate evolution.

Johanna Klughammer
Daria Romanovskaia
Christoph Bock
ResearchOpen Access16 Jan 2023
Nature Communications

Volume: 14, P: 1-23
A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Copy number alterations in stem cells impair neural crest differentiation and set the stage for neuroblastoma-like traits and tumours. This study hints at early tumourigenesis mechanisms and finds developmental gene signatures linked to prognosis.

Ingrid M. Saldana-Guerrero
Luis F. Montano-Gutierrez
Florian Halbritter
ResearchOpen Access03 May 2024
Nature Communications

Volume: 15, P: 1-25
Fine-scale phylogenetic architecture of a complex bacterial community

Silvia G. Acinas
Vanja Klepac-Ceraj
Martin F. Polz
Research29 Jul 2004
Nature

Volume: 430, P: 551-554
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo

Opto-acoustic imaging of fluorescent proteins deep within living organisms (Drosophila melanogaster and zebrafish) is reported. The approach uses multiple wavelength illumination of the sample to generate ultrasound waves which are then detected and converted into images.

Daniel Razansky
Martin Distel
Vasilis Ntziachristos
Research21 Jun 2009
Nature Photonics

Volume: 3, P: 412-417
Unraveling the functional dark matter through global metagenomics

A computational approach to generate reference-free protein families from the sequence space in metagenomes reveals an enormously diverse functional space.

Georgios A. Pavlopoulos
Fotis A. Baltoumas
Nikos C. Kyrpides
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 594-602
A comparative genomics multitool for scientific discovery and conservation

A whole-genome alignment of 240 phylogenetically diverse species of eutherian mammal—including 131 previously uncharacterized species—from the Zoonomia Project provides data that support biological discovery, medical research and conservation.

Diane P. Genereux
Aitor Serres
Elinor K. Karlsson
ResearchOpen Access11 Nov 2020
Nature

Volume: 587, P: 240-245
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Jing Shen
Sara Najafi
Ina Oehme
ResearchOpen Access07 Mar 2018
Cell Death & Differentiation

Volume: 25, P: 2053-2070
Fgf8 dynamics and critical slowing down may account for the temperature independence of somitogenesis

In Zebrafish, the dynamics of fgf8 and other gene transcripts as well as segmentation frequency, shortening of pre-somitic mesoderm and tail growth rate slows down with lower temperature. This may explain the temperature independence of somitogenesis.

Weiting Zhang
Pierluigi Scerbo
David Bensimon
ResearchOpen Access07 Feb 2022
Communications Biology

Volume: 5, P: 1-10
Correction to: LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

Diana Corallo
Michael Donadon
Sanja Aveic
Amendments and Corrections18 Nov 2019
Cell Death & Differentiation

Volume: 27, P: 1449
Metabolic and physiological interdependencies in the Bathymodiolus azoricus symbiosis

Ruby Ponnudurai
Manuel Kleiner
Stephanie Markert
ResearchOpen Access01 Nov 2016
The ISME Journal

Volume: 11, P: 463-477
LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

Diana Corallo
Michael Donadon
Sanja Aveic
Research10 Oct 2019
Cell Death & Differentiation

Volume: 27, P: 1225-1242
CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum

Enrico D. H. Konrad
Niels Nardini
Christiane Zweier
ResearchOpen Access26 Jun 2019
Genetics in Medicine

Volume: 21, P: 2723-2733
Meta-analysis of genome-wide association studies for personality

M H M de Moor
P T Costa
D I Boomsma
Research21 Dec 2010
Molecular Psychiatry

Volume: 17, P: 337-349
The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

C M Middeldorp
M H M de Moor
D I Boomsma
ResearchOpen Access18 Oct 2011
Translational Psychiatry

Volume: 1, P: e50
Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

C. Sturtzel
S. Grissenberger
M. Distel
ProtocolsOpen Access18 May 2023
npj Precision Oncology

Volume: 7, P: 1-16

Search

Comparative transcriptomics coupled to developmental grading via transgenic zebrafish reporter strains identifies conserved features in neutrophil maturation

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

Fine-scale phylogenetic architecture of a complex bacterial community

Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo

Unraveling the functional dark matter through global metagenomics

A comparative genomics multitool for scientific discovery and conservation

A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Fgf8 dynamics and critical slowing down may account for the temperature independence of somitogenesis

Correction to: LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

Metabolic and physiological interdependencies in the Bathymodiolus azoricus symbiosis

LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors

CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum

Meta-analysis of genome-wide association studies for personality

The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data

Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

Search

Quick links

Search

Filter By:

Search

Quick links