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Advanced filters: Author: Matheus Dyczynski Clear advanced filters

Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Laboratory and clinical strains of Crimean–Congo haemorrhagic fever virus use LDLR to bind and enter host cells in blood vessel organoids and mice. Infection can also occur through ApoE, possibly present on virus particles.

Vanessa M. Monteil
Shane C. Wright
Ali Mirazimi
ResearchOpen Access28 Mar 2024
Nature Microbiology

Volume: 9, P: 1499-1512
The natural compound periplogenin suppresses the growth of prostate carcinoma cells by directly targeting ATP1A1

Xinquan Zhang
Tinglin Pang
Liqun Zhang
ResearchOpen Access03 Sept 2024
Scientific Reports

Volume: 14, P: 1-8
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Host factors involved in filovirus infection are incompletely understood. Here, the authors used a haploid cell screening system to unveil CCZ1’s crucial role in regulating endosomal trafficking thus virus movement within cells and thereby impacting Marburg and Ebola infection.

Vanessa Monteil
Hyesoo Kwon
Ali Mirazimi
ResearchOpen Access25 Oct 2023
Nature Communications

Volume: 14, P: 1-16
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

Matheus Dyczynski
Mattias Vesterlund
Roland Nilsson
ResearchOpen Access28 Aug 2018
Cell Death & Disease

Volume: 9, P: 1-13

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